KEGG   Homo sapiens (human): 382
Entry
382               CDS       T01001                                 
Symbol
ARF6
Name
(RefSeq) ARF GTPase 6
  KO
K07941  ADP-ribosylation factor 6
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04072  Phospholipase D signaling pathway
hsa04144  Endocytosis
hsa04666  Fc gamma R-mediated phagocytosis
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05135  Yersinia infection
Network
nt06180  Pathogenic Escherichia coli
nt06181  Salmonella
nt06182  Shigella
  Element
N01066  ARNO-ARF-ACTB_G signaling pathway
N01067  Shigella IpgD to ARNO-ARF-ACTB_G signaling pathway
N01084  Escherichia EspG to ARNO-ARF-ACTB/G signaling pathway
N01129  Salmonella SopB to ARNO-ARF-ACTB/G signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    382 (ARF6)
   04072 Phospholipase D signaling pathway
    382 (ARF6)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    382 (ARF6)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    382 (ARF6)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    382 (ARF6)
   05132 Salmonella infection
    382 (ARF6)
   05131 Shigellosis
    382 (ARF6)
   05135 Yersinia infection
    382 (ARF6)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:hsa04131]
    382 (ARF6)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    382 (ARF6)
   04031 GTP-binding proteins [BR:hsa04031]
    382 (ARF6)
Membrane trafficking [BR:hsa04131]
 Endocytosis
  Lipid raft mediated endocytosis
   Arf6-dependent endocytosis
    382 (ARF6)
  Arf GTPases and associated proteins
   Arf GTPases
    382 (ARF6)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   382 (ARF6)
  Exosomal proteins of colorectal cancer cells
   382 (ARF6)
GTP-binding proteins [BR:hsa04031]
 Small (monomeric) G-proteins
  Arf/Sar Family
   Arf [OT]
    382 (ARF6)
SSDB
Motif
Pfam: Arf Roc G-alpha Ras SRPRB Gtr1_RagA MMR_HSR1 GTP_EFTU 6PF2K SpoOE-like CRISPR_Cas2
Other DBs
NCBI-GeneID: 382
NCBI-ProteinID: NP_001654
OMIM: 600464
HGNC: 659
Ensembl: ENSG00000165527
UniProt: P62330
Structure
Position
14:49893082..49897054
AA seq 175 aa
MGKVLSKIFGNKEMRILMLGLDAAGKTTILYKLKLGQSVTTIPTVGFNVETVTYKNVKFN
VWDVGGQDKIRPLWRHYYTGTQGLIFVVDCADRDRIDEARQELHRIINDREMRDAIILIF
ANKQDLPDAMKPHEIQEKLGLTRIRDRNWYVQPSCATSGDGLYEGLTWLTSNYKS
NT seq 528 nt   +upstreamnt  +downstreamnt
atggggaaggtgctatccaaaatcttcgggaacaaggaaatgcggatcctcatgttgggc
ctggacgcggccggcaagacaacaatcctgtacaagttgaagctgggccagtcggtgacc
accattcccactgtgggtttcaacgtggagacggtgacttacaaaaatgtcaagttcaac
gtatgggatgtgggcggccaggacaagatccggccgctctggcggcattactacactggg
acccaaggtctcatcttcgtagtggactgcgccgaccgcgaccgcatcgatgaggctcgc
caggagctgcaccgcattatcaatgaccgggagatgagggacgccataatcctcatcttc
gccaacaagcaggacctgcccgatgccatgaaaccccacgagatccaggagaaactgggc
ctgacccggattcgggacaggaactggtatgtgcagccctcctgtgccacctcaggggac
ggactctatgaggggctcacatggttaacctctaactacaaatcttaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (42)   
   RefGene (33)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (29)   
   RefSeq(nuc) (1)   
   GenBank (14)   
   EMBL (14)   
3D Structure (19)   
   PDB (19)   
Protein domain (11)   
   Pfam (11)   
All databases (105)   

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