KEGG   Homo sapiens (human): 3839
Entry
3839              CDS       T01001                                 
Symbol
KPNA3, IPOA4, SPG88, SRP1, SRP1gamma, SRP4, hSRP1
Name
(RefSeq) karyopherin subunit alpha 3
  KO
K23583  importin subunit alpha-4/3
Organism
hsa  Homo sapiens (human)
Pathway
hsa03013  Nucleocytoplasmic transport
hsa05132  Salmonella infection
hsa05207  Chemical carcinogenesis - receptor activation
Network
nt06181  Salmonella
nt06516  TNF signaling
  Element
N01118  Salmonella SpvD to TNF-NFKB signaling pathway
Disease
H00266  Hereditary spastic paraplegia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 Nucleocytoplasmic transport
    3839 (KPNA3)
 09160 Human Diseases
  09161 Cancer: overview
   05207 Chemical carcinogenesis - receptor activation
    3839 (KPNA3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    3839 (KPNA3)
SSDB
Motif
Pfam: Arm HEAT_EZ Arm_3 IBB ARM_ARMC5 HEAT HEAT_2 Adaptin_N TOR1L1_N Cnd1 Arm_2 XMAP215_CLASP_TOG Mo25
Other DBs
NCBI-GeneID: 3839
NCBI-ProteinID: NP_002258
OMIM: 601892
HGNC: 6396
Ensembl: ENSG00000102753
UniProt: O00505
Position
13:complement(49699320..49792682)
AA seq 521 aa
MAENPSLENHRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDS
DVDADFKAQNVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILV
KCLERDDNPSLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQNVCEQAVWA
LGNIIGDGPQCRDYVISLGVVKPLLSFISPSIPITFLRNVTWVIVNLCRNKDPPPPMETV
QEILPALCVLIYHTDINILVDTVWALSYLTDGGNEQIQMVIDSGVVPFLVPLLSHQEVKV
QTAALRAVGNIVTGTDEQTQVVLNCDVLSHFPNLLSHPKEKINKEAVWFLSNITAGNQQQ
VQAVIDAGLIPMIIHQLAKGDFGTQKEAAWAISNLTISGRKDQVEYLVQQNVIPPFCNLL
SVKDSQVVQVVLDGLKNILIMAGDEASTIAEIIEECGGLEKIEVLQQHENEDIYKLAFEI
IDQYFSGDDIDEDPCLIPEATQGGTYNFDPTANLQTKEFNF
NT seq 1566 nt   +upstreamnt  +downstreamnt
atggccgagaaccccagcttggagaaccaccgcatcaagagcttcaagaacaagggccgc
gatgtggaaacaatgcgaagacatagaaatgaagtgacagtggaactgcggaagaacaaa
agagatgaacacttattgaaaaagagaaatgttccccaagaagaaagtctagaagattca
gatgttgatgctgattttaaagcacaaaatgtaaccctagaagctatattgcagaatgcc
acaagtgataacccagtggtccaattgagtgctgtccaggcagcaagaaaactgttatcc
agtgacagaaatccaccgattgatgacttaataaaatctgggattttaccaattctagtc
aaatgtctagaaagggatgataatccttcattacagtttgaagctgcttgggcattaact
aacatagcatcaggaacttctgcacagactcaagctgttgtgcagtctaatgcagtacct
ctttttctgagacttcttcgttcaccacatcagaatgtttgtgaacaagcagtatgggct
ttgggaaacattataggtgatggtcctcaatgtagagattatgtcatatcactgggagtt
gtcaaacctcttctgtccttcatcagtccctccatccccatcaccttccttcggaacgtc
acatgggtcattgtcaatctctgcaggaataaggatcccccgccgcctatggagacagtt
caggagattttgccagctttatgtgtcctcatataccatacagatataaacattcttgta
gacactgtttgggctctgtcatacttgacagatggaggtaatgaacagatacagatggtt
attgattcaggagttgtgccctttcttgtgccccttctgagccatcaggaagtcaaagtt
caaacagcagccctcagagcagttggcaacatagtgactggcaccgacgagcagacccag
gttgttctcaattgtgatgtcctgtcacacttcccaaatctcttatcacacccaaaagag
aagataaataaggaagcagtgtggttcctttccaacataacagcaggcaaccagcaacaa
gttcaagctgtaatagatgctggattaattcctatgataattcatcagcttgctaagggg
gactttggaacacaaaaagaagctgcttgggcaatcagcaacttaacaataagtggcaga
aaagatcaggttgagtaccttgtacagcagaatgtaataccaccgttctgtaatttactg
tcagtgaaagattctcaagtggttcaggtggttctagatggtctaaaaaacattctgata
atggccggtgatgaagcaagcacaatagctgaaataatagaggaatgtggaggtttggag
aaaattgaagttttacagcaacatgaaaatgaagacatatataaattagcatttgaaatc
atagatcagtatttctctggtgatgatattgatgaagatccctgcctcattcctgaagca
acacaaggaggtacctacaattttgatccaacagccaaccttcaaacaaaagaatttaat
ttttaa

  All links  
Disease (2)   
   OMIM (2)   
Gene (17)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (8)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (29)   
   RefSeq(nuc) (3)   
   GenBank (13)   
   EMBL (13)   
Protein domain (13)   
   Pfam (13)   
All databases (66)   

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