KEGG   Homo sapiens (human): 3850
Entry
3850              CDS       T01001                                 
Symbol
KRT3, CK3, K3, MECD2
Name
(RefSeq) keratin 3
  KO
K07605  type II keratin, basic
Organism
hsa  Homo sapiens (human)
Pathway
hsa04382  Cornified envelope formation
Disease
H00726  Meesmann corneal dystrophy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04382 Cornified envelope formation
    3850 (KRT3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    3850 (KRT3)
   04147 Exosome [BR:hsa04147]
    3850 (KRT3)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Intermediate filaments
   Intermediate filaments
    Types I and II: Acidic and basic keratins
     3850 (KRT3)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of epithelial cells
   3850 (KRT3)
  Exosomal proteins of other body fluids (saliva and urine)
   3850 (KRT3)
  Exosomal proteins of colorectal cancer cells
   3850 (KRT3)
  Exosomal proteins of bladder cancer cells
   3850 (KRT3)
SSDB
Motif
Pfam: Filament Keratin_2_head CENP-F_leu_zip ATG16 TPR_MLP1_2 CCDC39 FKBP15 DUF8776 CCDC171 BRE1B DUF7260 ADIP DUF948 Alanine_zipper Ninein_long_CC CCDC89 DUF4407 KIF21A_4th DUF7217 Kazrin
Other DBs
NCBI-GeneID: 3850
NCBI-ProteinID: NP_476429
OMIM: 148043
HGNC: 6440
Ensembl: ENSG00000186442
UniProt: P12035
Position
12:complement(52789685..52796117)
AA seq 628 aa
MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNL
GGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFG
GAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSLL
QPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSS
ISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAA
ENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMD
NNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIE
LNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLAR
LLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGG
GYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSGFGSISGARYGVS
GGGFSSASNRGGSIKFSQSSQSSQRYSR
NT seq 1887 nt   +upstreamnt  +downstreamnt
atgagcagacaagccagcaagacatctggtggcgggagccagggtttctccggccgctct
gctgtggtctccggcagcagcaggatgagctgtgtggcccactctgggggagctggcgga
ggggcctatggcttccggagcggagcaggtggctttggcagtcgcagcctctacaacctg
ggcggcaacaagagcatctccatcagcgtggcagctggcggctcccgggctggaggcttt
gggggagggcggagcagctgtgcctttgcaggtggctatggaggtggctttgggagcggc
tatggaggtggctttggtggtggctttggtggtggcagaggaatgggaggtggctttggt
ggagctggtggctttggaggggctggtggctttggaggggctggtggctttggtggtcct
ggtggctttggtgggtctggtggctttggtgggcctggcagcttgggcagtcctggtggc
tttggccctgggggctttcctgggggaattcaggaagtgactatcaaccagagtctcctg
cagcccctcaatgtggagatcgacccccagattgggcaagtaaaggcccaggagcgggaa
cagatcaagaccctcaacaacaagtttgcctccttcattgacaaggtgcggttcctggag
caacagaacaaagtcctggagaccaagtggaacctgctccagcagcagggcacaagttcc
atctcaggcacaaacaaccttgagcctctttttgagaatcacatcaactacctgcggagc
tacctggacaacatcctcggggagagagggcgcctggactctgagctgaagaacatggag
gacctggtggaagacttcaagaagaaatatgaggatgaaatcaataaacgtacagctgct
gagaatgaatttgtgactctgaagaaggatgtggacagtgcctatatgaacaaggtggag
cttcaggccaaagtggatgccttgatagatgagatcgacttcttaaggaccctctacgac
gctgagctatctcagatgcagagccacatcagtgacacatctgtggtgctgtccatggac
aataatcgctccctggacctggacagcatcattgctgaagttcgtgcacagtatgaggat
atcgctcagagaagcaaggccgaagctgaggccctgtaccagaccaagttgggggagctg
cagaccacggctggcaggcatggggatgacctaagaaataccaagagcgagatcatagag
ctcaacagaatgatccagaggctgcgggcagagatcgagggtgtcaagaagcagaatgcc
aacctgcagacggccattgccgaggccgagcagcatggagagatggccctcaaggatgcc
aatgccaagctccaagagctgcaggctgctctacagcaggcgaaggatgacctggcgcgg
ctgctacgtgactaccaggagctgatgaatgtcaagctggccctggacgtggagatcgcc
acctaccgcaagctgctggagggcgaggagtacaggatgtctggagagtgtccgagtgct
gtcagcatctccgtggtcagcagcagcacgacttccgcctccgcaggtggctatggagga
ggttacggcggaggcatgggcggtggtttaggaggtggcttcagtgcgggcggcggctca
ggcagtggctttggccggggaggcggcggtggaatcggcggtggatttggcggcggcagc
agcggtttcagcggtggcagcggctttggctccatctctggcgcccgctatggagtcagt
ggcgggggcttcagctcggccagcaaccggggcggcagcatcaagttctcccagtcctcc
cagtcctcccagcgctactccagataa

  All links  
Disease (2)   
   OMIM (2)   
Gene (10)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (10)   
   RefSeq(nuc) (2)   
   GenBank (4)   
   EMBL (4)   
Protein domain (16)   
   Pfam (16)   
All databases (42)   

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