KEGG   Homo sapiens (human): 3972Help
Entry
3972              CDS       T01001                                 

Gene name
LHB, CGB4, HH23, LSH-B, LSH-beta
Definition
(RefSeq) luteinizing hormone subunit beta
  KO
K08521  lutropin subunit beta
Organism
hsa  Homo sapiens (human)
Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04912  GnRH signaling pathway
hsa04913  Ovarian steroidogenesis
hsa04917  Prolactin signaling pathway
hsa04929  GnRH secretion
Network
nt06323  KISS1-GnRH-LH/FSH-E2 signaling
  Element
N00873  GnRH-GnRHR-PLCB-PKC signaling pathway
N00875  Mutation-inactivated GnRHR to GnRH-GnRHR-PLCB-PKC signaling pathway
N00885  LHCGR-GNAS-PKA signaling pathway
N00886  Mutation-activated LHCGR to LHCGR-GNAS-PKA signaling pathway
Disease
H00255  Hypogonadotropic hypogonadism
H01973  Fertile eunuch syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    3972 (LHB)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    3972 (LHB)
 09150 Organismal Systems
  09152 Endocrine system
   04929 GnRH secretion
    3972 (LHB)
   04912 GnRH signaling pathway
    3972 (LHB)
   04913 Ovarian steroidogenesis
    3972 (LHB)
   04917 Prolactin signaling pathway
    3972 (LHB)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Cys_knot
Motif
Other DBs
NCBI-GeneID: 3972
NCBI-ProteinID: NP_000885
OMIM: 152780
HGNC: 6584
Ensembl: ENSG00000104826
Vega: OTTHUMG00000183334
Pharos: P01229(Tbio)
CPD: C18183
UniProt: P01229 A0A0F7RQE6
Position
19q13.33
AA seq 141 aa AA seqDB search
MEMLQGLLLLLLLSMGGAWASREPLRPWCHPINAILAVEKEGCPVCITVNTTICAGYCPT
MMRVLQAVLPPLPQVVCTYRDVRFESIRLPGCPRGVDPVVSFPVALSCRCGPCRRSTSDC
GGPKDHPLTCDHPQLSGLLFL
NT seq 426 nt NT seq  +upstreamnt  +downstreamnt
atggagatgctccaggggctgctgctgttgctgctgctgagcatgggcggggcatgggca
tccagggagccgcttcggccatggtgccaccccatcaatgccatcctggctgtcgagaag
gagggctgcccagtgtgcatcaccgtcaacaccaccatctgtgccggctactgccccacc
atgatgcgcgtgctgcaggcggtcctgccgcccctgcctcaggtggtgtgcacctaccgt
gatgtgcgcttcgagtccatccggctccctggctgcccgcgtggtgtggaccccgtggtc
tccttccctgtggctctcagctgtcgctgtggaccctgccgccgcagcacctctgactgt
gggggtcccaaagaccaccccttgacctgtgaccacccccaactctcaggcctcctcttc
ctctaa

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