KEGG   Homo sapiens (human): 4001
Entry
4001              CDS       T01001                                 

Symbol
LMNB1, ADLD, LMN, LMN2, LMNB, MCPH26
Name
(RefSeq) lamin B1
  KO
K07611  lamin B
Organism
hsa  Homo sapiens (human)
Pathway
hsa04210  Apoptosis
Disease
H01230  Adult-onset autosomal dominant leukodystrophy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    4001 (LMNB1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    4001 (LMNB1)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Intermediate filaments
   Intermediate filaments
    Type V: Nuclear lamins
     4001 (LMNB1)
SSDB
Motif
Pfam: Filament LTD Jnk-SapK_ap_N Spc7
Other DBs
NCBI-GeneID: 4001
NCBI-ProteinID: NP_005564
OMIM: 150340
HGNC: 6637
Ensembl: ENSG00000113368
Vega: OTTHUMG00000128969
Pharos: P20700(Tbio)
UniProt: P20700
Structure
PDB: 
3UMN 3JT0 3TYY 2KPW

Position
5q23.2
AA seq 586 aa
MATATPVPPRMGSRAGGPTTPLSPTRLSRLQEKEELRELNDRLAVYIDKVRSLETENSAL
QLQVTEREEVRGRELTGLKALYETELADARRALDDTARERAKLQIELGKCKAEHDQLLLN
YAKKESDLNGAQIKLREYEAALNSKDAALATALGDKKSLEGDLEDLKDQIAQLEASLAAA
KKQLADETLLKVDLENRCQSLTEDLEFRKSMYEEEINETRRKHETRLVEVDSGRQIEYEY
KLAQALHEMREQHDAQVRLYKEELEQTYHAKLENARLSSEMNTSTVNSAREELMESRMRI
ESLSSQLSNLQKESRACLERIQELEDLLAKEKDNSRRMLTDKEREMAEIRDQMQQQLNDY
EQLLDVKLALDMEISAYRKLLEGEEERLKLSPSPSSRVTVSRASSSRSVRTTRGKRKRVD
VEESEASSSVSISHSASATGNVCIEEIDVDGKFIRLKNTSEQDQPMGGWEMIRKIGDTSV
SYKYTSRYVLKAGQTVTIWAANAGVTASPPTDLIWKNQNSWGTGEDVKVILKNSQGEEVA
QRSTVFKTTIPEEEEEEEEAAGVVVEEELFHQQGTPRASNRSCAIM
NT seq 1761 nt   +upstreamnt  +downstreamnt
atggcgactgcgacccccgtgccgccgcggatgggcagccgcgctggcggccccaccacg
ccgctgagccccacgcgcctgtcgcggctccaggagaaggaggagctgcgcgagctcaat
gaccggctggcggtgtacatcgacaaggtgcgcagcctggagacggagaacagcgcgctg
cagctgcaggtgacggagcgcgaggaggtgcgcggccgtgagctcaccggcctcaaggcg
ctctacgagaccgagctggccgacgcgcgacgcgcgctcgacgacacggcccgcgagcgc
gccaagctgcagatcgagctgggcaagtgcaaggcggaacacgaccagctgctcctcaac
tatgctaagaaggaatctgatcttaatggcgcccagatcaagcttcgagaatatgaagca
gcactgaattcgaaagatgcagctcttgctactgcacttggtgacaaaaaaagtttagag
ggagatttggaggatctgaaggatcagattgcccagttggaagcctccttagctgcagcc
aaaaaacagttagcagatgaaactttacttaaagtagatttggagaatcgttgtcagagc
cttactgaggacttggagtttcgcaaaagcatgtatgaagaggagattaacgagaccaga
aggaagcatgaaacgcgcttggtagaggtggattctgggcgtcaaattgagtatgagtac
aagctggcgcaagcccttcatgagatgagagagcaacatgatgcccaagtgaggctgtat
aaggaggagctggagcagacttaccatgccaaacttgagaatgccagactgtcatcagag
atgaatacttctactgtcaacagtgccagggaagaactgatggaaagccgcatgagaatt
gagagcctttcatcccagctttctaatctacagaaagagtctagagcatgtttggaaagg
attcaagaattagaggacttgcttgctaaagaaaaagacaactctcgtcgcatgctgaca
gacaaagagagagagatggcggaaataagggatcaaatgcagcaacagctgaatgactat
gaacagcttcttgatgtaaagttagccctggacatggaaatcagtgcttacaggaaactc
ttagaaggcgaagaagagaggttgaagctgtctccaagcccttcttcccgtgtgacagta
tcccgagcatcctcaagtcgtagtgtacgtacaactagaggaaagcggaagagggttgat
gtggaagaatcagaggcgagtagtagtgttagcatctctcattccgcctcagccactgga
aatgtttgcatcgaagaaattgatgttgatgggaaatttatccgcttgaagaacacttct
gaacaggatcaaccaatgggaggctgggagatgatcagaaaaattggagacacatcagtc
agttataaatatacctcaagatatgtgctgaaggcaggccagactgttacaatttgggct
gcaaacgctggtgtcacagccagccccccaactgacctcatctggaagaaccagaactcg
tggggcactggcgaagatgtgaaggttatattgaaaaattctcagggagaggaggttgct
caaagaagtacagtctttaaaacaaccatacctgaagaagaggaggaggaggaagaagca
gctggagtggttgttgaggaagaacttttccaccagcagggaaccccaagagcatccaat
agaagctgtgcaattatgtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (4)   
   KEGG DISEASE (1)   
   OMIM (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (11)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (21)   
   RefSeq(nuc) (3)   
   GenBank (9)   
   EMBL (9)   
Protein domain (4)   
   Pfam (4)   
All databases (61)   

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