KEGG   Homo sapiens (human): 4005
Entry
4005              CDS       T01001                                 

Gene name
LMO2, LMO-2, RBTN2, RBTNL1, RHOM2, TTG2
Definition
(RefSeq) LIM domain only 2
  KO
K15612  rhombotin-2
Organism
hsa  Homo sapiens (human)
Pathway
hsa05202  Transcriptional misregulation in cancer
Network
nt06240  Transcription
  Element
N00119  MLL-AF4 fusion to transcriptional activation
N00121  LMO2-rearrangement to transcriptional activation
N00122  LMO2-rearrangement to transcriptional repression
Disease
H00002  T-cell acute lymphoblastic leukemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    4005 (LMO2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:hsa04990]
    4005 (LMO2)
Domain-containing proteins not elsewhere classified [BR:hsa04990]
 LIM domain-containing proteins
  Nuclear LMO family proteins
   4005 (LMO2)
SSDB
Motif
Pfam: LIM C1_4 TDH
Other DBs
NCBI-GeneID: 4005
NCBI-ProteinID: NP_001135787
OMIM: 180385
HGNC: 6642
Ensembl: ENSG00000135363
Vega: OTTHUMG00000157176
Pharos: P25791(Tbio)
UniProt: P25791
Structure
PDB: 
2XJY 4KFZ 2YPA 2XJZ

Position
11p13
AA seq 158 aa
MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLC
GCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECF
KCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI
NT seq 477 nt   +upstreamnt  +downstreamnt
atgtcctcggccatcgaaaggaagagcctggacccttcagaggaaccagtggatgaggtg
ctgcagatccccccatccctgctgacatgcggcggctgccagcagaacattggggaccgc
tacttcctgaaggccatcgaccagtactggcacgaggactgcctgagctgcgacctctgt
ggctgccggctgggtgaggtggggcggcgcctctactacaaactgggccggaagctctgc
cggagagactatctcaggctttttgggcaagacggtctctgcgcatcctgtgacaagcgg
attcgtgcctatgagatgacaatgcgggtgaaagacaaagtgtatcacctggaatgtttc
aaatgcgccgcctgtcagaagcatttctgtgtaggtgacagatacctcctcatcaactct
gacatagtgtgcgaacaggacatctacgagtggactaagatcaatgggatgatatag

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (3)   
   KEGG NETWORK (3)   
Disease (2)   
   KEGG DISEASE (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (13)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (31)   
   RefSeq(nuc) (11)   
   GenBank (10)   
   EMBL (10)   
Protein domain (3)   
   Pfam (3)   
All databases (72)   

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