KEGG   Homo sapiens (human): 4048
Entry
4048              CDS       T01001                                 
Symbol
LTA4H
Name
(RefSeq) leukotriene A4 hydrolase
  KO
K01254  leukotriene-A4 hydrolase [EC:3.3.2.6]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00590  Arachidonic acid metabolism
hsa01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    4048 (LTA4H)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    4048 (LTA4H)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.3  Acting on ether bonds
   3.3.2  Ether hydrolases
    3.3.2.6  leukotriene-A4 hydrolase
     4048 (LTA4H)
Peptidases and inhibitors [BR:hsa01002]
 Metallo peptidases
  Family M1
   4048 (LTA4H)
SSDB
Motif
Pfam: Peptidase_M1 Leuk-A4-hydro_C Peptidase_M1_N
Other DBs
NCBI-GeneID: 4048
NCBI-ProteinID: NP_000886
OMIM: 151570
HGNC: 6710
Ensembl: ENSG00000111144
UniProt: P09960 A0A140VK27
Structure
Position
12:complement(96000753..96043520)
AA seq 611 aa
MPEIVDTCSLASPASVCRTKHLHLRCSVDFTRRTLTGTAALTVQSQEDNLRSLVLDTKDL
TIEKVVINGQEVKYALGERQSYKGSPMEISLPIALSKNQEIVIEISFETSPKSSALQWLT
PEQTSGKEHPYLFSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGETP
DPEDPSRKIYKFIQKVPIPCYLIALVVGALESRQIGPRTLVWSEKEQVEKSAYEFSETES
MLKIAEDLGGPYVWGQYDLLVLPPSFPYGGMENPCLTFVTPTLLAGDKSLSNVIAHEISH
SWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGEKFRHFNALGGWGELQNSVKTFGET
HPFTKLVVDLTDIDPDVAYSSVPYEKGFALLFYLEQLLGGPEIFLGFLKAYVEKFSYKSI
TTDDWKDFLYSYFKDKVDVLNQVDWNAWLYSPGLPPIKPNYDMTLTNACIALSQRWITAK
EDDLNSFNATDLKDLSSHQLNEFLAQTLQRAPLPLGHIKRMQEVYNFNAINNSEIRFRWL
RLCIQSKWEDAIPLALKMATEQGRMKFTRPLFKDLAAFDKSHDQAVRTYQEHKASMHPVT
AMLVGKDLKVD
NT seq 1836 nt   +upstreamnt  +downstreamnt
atgcccgagatagtggatacctgttcgttggcctctccggcttccgtctgccggaccaag
cacctgcacctgcgctgcagcgtcgactttactcgccggacgctgaccgggactgctgct
ctcacggtccagtctcaggaggacaatctgcgcagcctggttttggatacaaaggacctt
acaatagaaaaagtagtgatcaatggacaagaagtcaaatatgctcttggagaaagacaa
agttacaagggatcgccaatggaaatctctcttcctatcgctttgagcaaaaatcaagaa
attgttatagaaatttcttttgagacctctccaaaatcttctgctctccagtggctcact
cctgaacagacttctgggaaggaacacccatatctctttagtcagtgccaggccatccac
tgcagagcaatccttccttgtcaggacactccttctgtgaaattaacctatactgcagag
gtgtctgtccctaaagaactggtggcacttatgagtgctattcgtgatggagaaacacct
gacccagaagacccaagcaggaaaatatacaaattcatccaaaaagttccaataccctgc
tacctgattgctttagttgttggagctttagaaagcaggcaaattggcccaagaactttg
gtgtggtctgagaaagagcaggtggaaaagtctgcttatgagttttctgagactgaatct
atgcttaaaatagcagaagatctgggaggaccgtatgtatggggacagtatgacctattg
gtcctgccaccatccttcccttatggtggcatggagaatccttgccttacttttgtaact
cctactctactggcaggcgacaagtcactctccaatgtcattgcacatgaaatatctcat
agctggacagggaatctagtgaccaacaaaacttgggatcacttttggttaaatgaggga
catactgtgtacttggaacgccacatttgcggacgattgtttggtgaaaagttcagacat
tttaatgctctgggaggatggggagaactacagaattcggtaaagacatttggggagaca
catcctttcaccaaacttgtggttgatctgacagatatagaccctgatgtagcttattct
tcagttccctatgagaagggctttgctttacttttttaccttgaacaactgcttggagga
ccagagattttcctaggattcttaaaagcttatgttgagaagttttcctataagagcata
actactgatgactggaaggatttcctgtattcctattttaaagataaggttgatgttctc
aatcaagttgattggaatgcctggctctactctcctggactgcctcccataaagcccaat
tatgatatgactctgacaaatgcttgtattgccttaagtcaaagatggattactgccaaa
gaagatgatttaaattcattcaatgccacagacctgaaggatctctcttctcatcaattg
aatgagtttttagcacagacgctccagagggcacctcttccattggggcacataaagcga
atgcaagaggtgtacaacttcaatgccattaacaattctgaaatacgattcagatggctg
cggctctgcattcaatccaagtgggaggacgcaattcctttggcgctaaagatggcaact
gaacaaggaagaatgaagtttacccggcccttattcaaggatcttgctgcctttgacaaa
tcccatgatcaagctgtccgaacctaccaagagcacaaagcaagcatgcatcccgtgact
gcaatgctggtggggaaagacttaaaagtggattaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (27)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (12)   
   OC (1)   
Protein sequence (14)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (11)   
DNA sequence (50)   
   RefSeq(nuc) (14)   
   GenBank (18)   
   EMBL (18)   
3D Structure (77)   
   PDB (77)   
Protein domain (3)   
   Pfam (3)   
All databases (172)   

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