KEGG   Homo sapiens (human): 4072
Entry
4072              CDS       T01001                                 
Symbol
EPCAM, Ber-Ep4, BerEp4, DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, LYNCH8, M4S1, MIC18, MK-1, MOC-31, TACSTD1, TROP1
Name
(RefSeq) epithelial cell adhesion molecule
  KO
K06737  epithelial cell adhesion molecule
Organism
hsa  Homo sapiens (human)
Pathway
hsa03272  Virion - Hepatitis viruses
Disease
H01174  Congenital diarrhea
H02565  Hereditary nonpolyposis colorectal cancer
Drug target
Catumaxomab: D09207
Edrecolomab: D03958
Tucotuzumab celmoleukin: D09027
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03272 Virion - Hepatitis viruses
    4072 (EPCAM)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    4072 (EPCAM)
   04090 CD molecules [BR:hsa04090]
    4072 (EPCAM)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of epithelial cells
   4072 (EPCAM)
  Exosomal proteins of colorectal cancer cells
   4072 (EPCAM)
CD molecules [BR:hsa04090]
 Proteins
  4072 (EPCAM)
SSDB
Motif
Pfam: EPCAM-Trop-2_C EpCAM_N Thyroglobulin_1 DAG1 BCLP Glycophorin_A Trp_oprn_chp Baculo_11_kDa
Other DBs
NCBI-GeneID: 4072
NCBI-ProteinID: NP_002345
OMIM: 185535
HGNC: 11529
Ensembl: ENSG00000119888
UniProt: P16422
Structure
Position
2:47369311..47387020
AA seq 314 aa
MAPPQVLAFGLLLAAATATFAAAQEECVCENYKLAVNCFVNNNRQCQCTSVGAQNTVICS
KLAAKCLVMKAEMNGSKLGRRAKPEGALQNNDGLYDPDCDESGLFKAKQCNGTSMCWCVN
TAGVRRTDKDTEITCSERVRTYWIIIELKHKAREKPYDSKSLRTALQKEITTRYQLDPKF
ITSILYENNVITIDLVQNSSQKTQNDVDIADVAYYFEKDVKGESLFHSKKMDLTVNGEQL
DLDPGQTLIYYVDEKAPEFSMQGLKAGVIAVIVVVVIAVVAGIVVLVISRKKRMAKYEKA
EIKEMGEMHRELNA
NT seq 945 nt   +upstreamnt  +downstreamnt
atggcgcccccgcaggtcctcgcgttcgggcttctgcttgccgcggcgacggcgactttt
gccgcagctcaggaagaatgtgtctgtgaaaactacaagctggccgtaaactgctttgtg
aataataatcgtcaatgccagtgtacttcagttggtgcacaaaatactgtcatttgctca
aagctggctgccaaatgtttggtgatgaaggcagaaatgaatggctcaaaacttgggaga
agagcaaaacctgaaggggccctccagaacaatgatgggctttatgatcctgactgcgat
gagagcgggctctttaaggccaagcagtgcaacggcacctccatgtgctggtgtgtgaac
actgctggggtcagaagaacagacaaggacactgaaataacctgctctgagcgagtgaga
acctactggatcatcattgaactaaaacacaaagcaagagaaaaaccttatgatagtaaa
agtttgcggactgcacttcagaaggagatcacaacgcgttatcaactggatccaaaattt
atcacgagtattttgtatgagaataatgttatcactattgatctggttcaaaattcttct
caaaaaactcagaatgatgtggacatagctgatgtggcttattattttgaaaaagatgtt
aaaggtgaatccttgtttcattctaagaaaatggacctgacagtaaatggggaacaactg
gatctggatcctggtcaaactttaatttattatgttgatgaaaaagcacctgaattctca
atgcagggtctaaaagctggtgttattgctgttattgtggttgtggtgatagcagttgtt
gctggaattgttgtgctggttatttccagaaagaagagaatggcaaagtatgagaaggct
gagataaaggagatgggtgagatgcatagggaactcaatgcataa

  All links  
Disease (3)   
   OMIM (3)   
Gene (13)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (39)   
   RefSeq(nuc) (1)   
   GenBank (19)   
   EMBL (19)   
3D Structure (2)   
   PDB (2)   
Protein domain (8)   
   Pfam (8)   
All databases (68)   

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