| Entry |
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| Symbol |
MAD2L1, HSMAD2, MAD2
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| Name |
(RefSeq) mitotic arrest deficient 2 like 1
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| KO |
| K02537 | mitotic spindle assembly checkpoint protein MAD2 |
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| Organism |
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| Pathway |
| hsa04914 | Progesterone-mediated oocyte maturation |
| hsa05166 | Human T-cell leukemia virus 1 infection |
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| Network |
nt06160 Human T-cell leukemia virus 1 (HTLV-1) nt06230 Cell cycle (cancer) nt06515 Regulation of kinetochore-microtubule interactions |
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| Element |
| N00493 | Spindle assembly checkpoint signaling |
| N01529 | Recruitment and formation of the MCC |
| N01532 | Kinetochore targeting of MAD1-MAD2 |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09140 Cellular Processes
09143 Cell growth and death
04110 Cell cycle
4085 (MAD2L1)
04114 Oocyte meiosis
4085 (MAD2L1)
09150 Organismal Systems
09152 Endocrine system
04914 Progesterone-mediated oocyte maturation
4085 (MAD2L1)
09160 Human Diseases
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
4085 (MAD2L1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:hsa03036]
4085 (MAD2L1)
Chromosome and associated proteins [BR:hsa03036]
Eukaryotic type
Centromeric chromatin formation proteins
SAC (spindle assembly checkpoint) factors
Core SAC proteins
4085 (MAD2L1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| Position |
4:complement(120055623..120066848)
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| AA seq |
205 aa
MALQLSREQGITLRGSAEIVAEFFSFGINSILYQRGIYPSETFTRVQKYGLTLLVTTDLE
LIKYLNNVVEQLKDWLYKCSVQKLVVVISNIESGEVLERWQFDIECDKTAKDDSAPREKS
QKAIQDEIRSVIRQITATVTFLPLLEVSCSFDLLIYTDKDLVVPEKWEESGPQFITNSEE
VRLRSFTTTIHKVNSMVAYKIPVND |
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| NT seq |
618 nt +upstreamnt +downstreamnt
atggcgctgcagctctcccgggagcagggaatcaccctgcgcgggagcgccgaaatcgtg
gccgagttcttctcattcggcatcaacagcattttatatcagcgtggcatatatccatct
gaaacctttactcgagtgcagaaatacggactcaccttgcttgtaactactgatcttgag
ctcataaaatacctaaataatgtggtggaacaactgaaagattggttatacaagtgttca
gttcagaaactggttgtagttatctcaaatattgaaagtggtgaggtcctggaaagatgg
cagtttgatattgagtgtgacaagactgcaaaagatgacagtgcacccagagaaaagtct
cagaaagctatccaggatgaaatccgttcagtgatcagacagatcacagctacggtgaca
tttctgccactgttggaagtttcttgttcatttgatctgctgatttatacagacaaagat
ttggttgtacctgaaaaatgggaagagtcgggaccacagtttattaccaattctgaggaa
gtccgccttcgttcatttactactacaatccacaaagtaaatagcatggtggcctacaaa
attcctgtcaatgactga |
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