KEGG   Homo sapiens (human): 4091
Entry
4091              CDS       T01001                                 

Symbol
SMAD6, AOVD2, HsT17432, MADH6, MADH7
Name
(RefSeq) SMAD family member 6
  KO
K04677  mothers against decapentaplegic homolog 6
Organism
hsa  Homo sapiens (human)
Pathway
hsa04350  TGF-beta signaling pathway
Disease
H00554  Aortic valve disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    4091 (SMAD6)
SSDB
Motif
Pfam: MH2 MH1
Other DBs
NCBI-GeneID: 4091
NCBI-ProteinID: NP_005576
OMIM: 602931
HGNC: 6772
Ensembl: ENSG00000137834
Vega: OTTHUMG00000133218
Pharos: O43541(Tbio)
UniProt: O43541
Position
15q22.31
AA seq 496 aa
MFRSKRSGLVRRLWRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEV
RPVAPRRPRDAVGQRGAQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESD
CETVTCCLFSERDAAGAPRDASDPLAGAALEPAGGGRSREARSRLLLLEQELKTVTYSLL
KRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGGQPAPPQLLLGRLFRWPDLQHAVE
LKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSDSTLSY
TETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDL
PQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAP
GGRALVVRKVPPGYSIKVFDFERSGLQHAPEPDAADGPYDPNSVRISFAKGWGPCYSRQF
ITSCPCWLEILLNNPR
NT seq 1491 nt   +upstreamnt  +downstreamnt
atgttcaggtccaaacgctcggggctggtgcggcgactttggcgaagtcgtgtggtcccc
gaccgggaggaaggcggcagcggcggcggcggtggcggcgacgaggatgggagcttgggc
agccgagctgagccggccccgcgggcaagagagggcggaggctgcggccgctccgaagtc
cgcccggtagccccgcggcggccccgggacgcagtgggacagcgaggcgcccagggcgcg
gggaggcgccggcgcgcagggggccccccgaggcccatgtcggagccaggggccggcgct
gggagctccctgctggacgtggcggagccgggaggcccgggctggctgcccgagagtgac
tgcgagacggtgacctgctgtctcttttcggagcgggacgccgccggcgcgccccgggac
gccagcgaccccctggccggggcggccctggagccggcgggcggcgggcggagtcgcgaa
gcgcgctcgcggctgctgctgctggagcaggaactcaaaaccgtcacgtactcgctgctg
aagcggctcaaggagcgctcgctggacacgctgctggaggcggtggagtcccgcggcggc
gtgccgggcggctgcgtgctggtgccgcgcgccgacctccgcctgggcggccagcccgcg
ccgccgcagctgctgctcggccgcctctttcgctggcccgacctgcagcacgccgtggag
ctgaagcccctgtgcggctgccacagcttcgccgccgccgccgacggccctaccgtgtgc
tgcaacccctaccacttcagccggctctgcgggcccgaatctccgccacctccctactct
cggctgtctcctcgcgacgagtacaagccactggatctgtccgattccacattgtcttac
actgaaacggaggctaccaactccctcatcactgctccgggtgaattctcagacgccagc
atgtctccggacgccaccaagccgagccactggtgcagcgtggcgtactgggagcaccgg
acgcgcgtgggccgcctctatgcggtgtacgaccaggccgtcagcatcttctacgaccta
cctcagggcagcggcttctgcctgggccagctcaacctggagcagcgcagcgagtcggtg
cggcgaacgcgcagcaagatcggcttcggcatcctgctcagcaaggagcccgacggcgtg
tgggcctacaaccgcggcgagcaccccatcttcgtcaactccccgacgctggacgcgccc
ggcggccgcgccctggtcgtgcgcaaggtgccccccggctactccatcaaggtgttcgac
ttcgagcgctcgggcctgcagcacgcgcccgagcccgacgccgccgacggcccctacgac
cccaacagcgtccgcatcagcttcgccaagggctgggggccctgctactcccggcagttc
atcacctcctgcccctgctggctggagatcctcctcaacaaccccagatag

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (4)   
   KEGG DISEASE (1)   
   OMIM (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (31)   
   RefSeq(nuc) (5)   
   GenBank (13)   
   EMBL (13)   
Protein domain (2)   
   Pfam (2)   
All databases (71)   

Download RDF
KEGG   Homo sapiens (human): 4092
Entry
4092              CDS       T01001                                 

Symbol
SMAD7, CRCS3, MADH7, MADH8
Name
(RefSeq) SMAD family member 7
  KO
K19631  mothers against decapentaplegic homolog 7
Organism
hsa  Homo sapiens (human)
Pathway
hsa04350  TGF-beta signaling pathway
hsa04390  Hippo signaling pathway
Drug target
Mongersen (DG02694): D10955 D10956
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04350 TGF-beta signaling pathway
    4092 (SMAD7)
   04390 Hippo signaling pathway
    4092 (SMAD7)
SSDB
Motif
Pfam: MH2 MH1
Other DBs
NCBI-GeneID: 4092
NCBI-ProteinID: NP_005895
OMIM: 602932
HGNC: 6773
Ensembl: ENSG00000101665
Vega: OTTHUMG00000132655
Pharos: O15105(Tbio)
UniProt: O15105
Position
18q21.1
AA seq 426 aa
MFRTKRSALVRRLWRSRAPGGEDEEEGAGGGGGGGELRGEGATDSRAHGAGGGGPGRAGC
CLGKAVRGAKGHHHPHPPAAGAGAAGGAEADLKALTHSVLKKLKERQLELLLQAVESRGG
TRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLCKVFRWPDLRHSSEVKRLCCC
ESYGKINPELVCCNPHHLSRLCELESPPPPYSRYPMDFLKPTADCPDAVPSSAETGGTNY
LAPGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRLYCVQEPSLDIFYDLPQGNGFCLGQ
LNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRSSYPIFIKSATLDNPDSRTLLVHKV
FPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQISFVKGWGQCYTRQFISSCPCWLE
VIFNSR
NT seq 1281 nt   +upstreamnt  +downstreamnt
atgttcaggaccaaacgatctgcgctcgtccggcgtctctggaggagccgtgcgcccggc
ggcgaggacgaggaggagggcgcagggggaggtggaggaggaggcgagctgcggggagaa
ggggcgacggacagccgagcgcatggggccggtggcggcggcccgggcagggctggatgc
tgcctgggcaaggcggtgcgaggtgccaaaggtcaccaccatccccacccgccagccgcg
ggcgccggcgcggccgggggcgccgaggcggatctgaaggcgctcacgcactcggtgctc
aagaaactgaaggagcggcagctggagctgctgctccaggccgtggagtcccgcggcggg
acgcgcaccgcgtgcctcctgctgcccggccgcctggactgcaggctgggcccgggggcg
cccgccggcgcgcagcctgcgcagccgccctcgtcctactcgctccccctcctgctgtgc
aaagtgttcaggtggccggatctcaggcattcctcggaagtcaagaggctgtgttgctgt
gaatcttacgggaagatcaaccccgagctggtgtgctgcaacccccatcaccttagccga
ctctgcgaactagagtctcccccccctccttactccagatacccgatggattttctcaaa
ccaactgcagactgtccagatgctgtgccttcctccgctgaaacagggggaacgaattat
ctggcccctggggggctttcagattcccaacttcttctggagcctggggatcggtcacac
tggtgcgtggtggcatactgggaggagaagacgagagtggggaggctctactgtgtccag
gagccctctctggatatcttctatgatctacctcaggggaatggcttttgcctcggacag
ctcaattcggacaacaagagtcagctggtgcagaaggtgcggagcaaaatcggctgcggc
atccagctgacgcgggaggtggatggtgtgtgggtgtacaaccgcagcagttaccccatc
ttcatcaagtccgccacactggacaacccggactccaggacgctgttggtacacaaggtg
ttccccggtttctccatcaaggctttcgactacgagaaggcgtacagcctgcagcggccc
aatgaccacgagtttatgcagcagccgtggacgggctttaccgtgcagatcagctttgtg
aagggctggggccagtgctacacccgccagttcatcagcagctgcccgtgctggctagag
gtcatcttcaacagccggtag

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (2)   
   OMIM (2)   
Drug (2)   
   KEGG DRUG (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (23)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (20)   
   RefSeq(nuc) (4)   
   GenBank (8)   
   EMBL (8)   
Protein domain (2)   
   Pfam (2)   
All databases (59)   

Download RDF
DBGET integrated database retrieval system