KEGG   Homo sapiens (human): 4139
Entry
4139              CDS       T01001                                 
Symbol
MARK1, MARK, Par-1c, Par1c
Name
(RefSeq) microtubule affinity regulating kinase 1
  KO
K08798  MAP/microtubule affinity-regulating kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    4139 (MARK1)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    4139 (MARK1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     4139 (MARK1)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CAMK group
  CAMKL family
   4139 (MARK1)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Others
     4139 (MARK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr KA1 UBA Kinase-like ABC1 UBA_2 MELK_UBA Haspin_kinase Kdo
Other DBs
NCBI-GeneID: 4139
NCBI-ProteinID: NP_061120
OMIM: 606511
HGNC: 6896
Ensembl: ENSG00000116141
UniProt: Q9P0L2
Structure
Position
1:220528136..220664461
AA seq 795 aa
MSARTPLPTVNERDTENHTSVDGYTEPHIQPTKSSSRQNIPRCRNSITSATDEQPHIGNY
RLQKTIGKGNFAKVKLARHVLTGREVAVKIIDKTQLNPTSLQKLFREVRIMKILNHPNIV
KLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMKEKEARAKFRQIVSAVQYCHQKYIVH
RDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDTFCGSPPYAAPELFQGKKYDGPEVDV
WSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRIPFYMSTDCENLLKKLLVLNPIKRG
SLEQIMKDRWMNVGHEEEELKPYTEPDPDFNDTKRIDIMVTMGFARDEINDALINQKYDE
VMATYILLGRKPPEFEGGESLSSGNLCQRSRPSSDLNNSTLQSPAHLKVQRSISANQKQR
RFSDHAGPSIPPAVSYTKRPQANSVESEQKEEWDKDVARKLGSTTVGSKSEMTASPLVGP
ERKKSSTIPSNNVYSGGSMARRNTYVCERTTDRYVALQNGKDSSLTEMSVSSISSAGSSV
ASAVPSARPRHQKSMSTSGHPIKVTLPTIKDGSEAYRPGTTQRVPAASPSAHSISTATPD
RTRFPRGSSSRSTFHGEQLRERRSVAYNGPPASPSHETGAFAHARRGTSTGIISKITSKF
VRRDPSEGEASGRTDTSRSTSGEPKERDKEEGKDSKPRSLRFTWSMKTTSSMDPNDMMRE
IRKVLDANNCDYEQKERFLLFCVHGDARQDSLVQWEMEVCKLPRLSLNGVRFKRISGTSI
AFKNIASKIANELKL
NT seq 2388 nt   +upstreamnt  +downstreamnt
atgtcggcccggacgccattgccgacggtgaacgagcgggacacggaaaatcatacatct
gtggatggatatactgaaccacacatccagcctaccaagtcgagtagcagacagaacatc
ccccggtgtagaaactccattacgtcagcaacagatgaacagcctcacattggaaattac
cgtttacaaaaaacaatagggaagggaaattttgccaaagtcaaattggcaagacacgtt
ctaactggtagagaggttgctgtgaaaataatagacaaaactcagctaaatcctaccagt
ctacaaaagttatttcgagaagtacgaataatgaagatactgaatcatcctaatatagta
aaattgtttgaagttattgaaacagagaagactctctatttagtcatggaatacgcgagt
gggggtgaagtatttgattacttagttgcccatggaagaatgaaagagaaagaggcccgt
gcaaaatttaggcagattgtatctgctgtacagtattgtcatcaaaagtacattgttcac
cgtgatcttaaggctgaaaaccttctccttgatggtgatatgaatattaaaattgctgac
tttggttttagtaatgaatttacagttgggaacaaattggacacattttgtggaagccca
ccctatgctgctcccgagcttttccaaggaaagaagtatgatgggcctgaagtggatgtg
tggagtctgggcgtcattctctatacattagtcagtggctccttgcctttcgatggccag
aatttaaaggaactgcgagagcgagttttacgagggaagtaccgtattcccttctatatg
tccacagactgtgaaaatcttctgaagaaattattagtcctgaatccaataaagagaggc
agcttggaacaaataatgaaagatcgatggatgaatgttggtcatgaagaggaagaacta
aagccatatactgagcctgatccggatttcaatgacacaaaaagaatagacattatggtc
accatgggctttgcacgagatgaaataaatgatgccttaataaatcagaagtatgatgaa
gttatggctacttatattcttctaggtagaaaaccacctgaatttgaaggtggtgaatcg
ttatccagtggaaacttgtgtcagaggtcccggcccagtagtgacttaaacaacagcact
cttcagtcccctgctcacctgaaggtccagagaagtatctcagcaaatcagaagcagcgg
cgtttcagtgatcatgctggtccatccattcctcctgctgtatcatataccaaaagacct
caggctaacagtgtggaaagtgaacagaaagaggagtgggacaaagatgtggctcgaaaa
cttggcagcacaacagttggatcaaaaagcgagatgactgcaagccctcttgtagggcca
gagaggaaaaaatcttcaactattccaagtaacaatgtgtattctggaggtagcatggca
agaaggaatacatatgtctgtgaaaggaccacagatcgatacgtagcattgcagaatgga
aaagacagcagccttacggagatgtctgtgagtagcatatcttctgcaggctcttctgtg
gcctctgctgtcccctcagcacgaccccgccaccagaagtccatgtccacttctggtcat
cctattaaagtcacactgccaaccattaaagacggctctgaagcttaccggcctggtaca
acccagagagtgcctgctgcttccccatctgctcacagtattagtactgcgactccagac
cggacccgttttccccgagggagctcaagccgaagcactttccatggtgaacagctccgg
gagcgacgcagcgttgcttataatgggccacctgcttcaccatcccatgaaacgggtgca
tttgcacatgccagaaggggaacgtcaactggtataataagcaaaatcacatccaaattt
gttcgcagggatccaagtgaaggcgaagccagtggcagaaccgacacctcaagaagtaca
tcaggggaaccaaaagaaagagacaaggaagagggtaaagattctaagccgcgttctttg
cggttcacatggagtatgaagaccactagttcaatggaccctaatgacatgatgagagaa
atccgaaaagtgttagatgcaaataactgtgattatgagcaaaaagagagatttttgctt
ttctgtgtccatggagacgctagacaggatagcctcgtgcagtgggagatggaagtctgc
aagttgccacgactgtcacttaatggggttcgcttcaagcgaatatctgggacatctatt
gcctttaagaacattgcatcaaaaatagcaaatgagcttaagctgtaa

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Ontology (4)   
   KEGG BRITE (4)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (21)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (19)   
DNA sequence (51)   
   RefSeq(nuc) (19)   
   GenBank (16)   
   EMBL (16)   
3D Structure (3)   
   PDB (3)   
Protein domain (10)   
   Pfam (10)   
All databases (105)   

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