KEGG   Homo sapiens (human): 4160Help
Entry
4160              CDS       T01001                                 

Gene name
MC4R
Definition
(RefSeq) melanocortin 4 receptor
  KO
K04202  melanocortin 4 receptor
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
Disease
H02106  Genetic obesity
Drug target
Alsactide: D07417
Bremelanotide: D06569
Giractide (DG01344): D09801 D09937
Seractide acetate: D05827
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    4160 (MC4R)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    4160 (MC4R)
G protein-coupled receptors [BR:hsa04030]
 Class A. Rhodopsin family
  Pituitary hormone
   Melanocortin
    4160 (MC4R)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 7tm_1 7tm_4 7TM_GPCR_Srsx 7TM_GPCR_Srx
Motif
Other DBs
NCBI-GeneID: 4160
NCBI-ProteinID: NP_005903
OMIM: 155541
HGNC: 6932
Ensembl: ENSG00000166603
Vega: OTTHUMG00000132766
Pharos: P32245(Tchem)
UniProt: P32245
Position
18q21.32
AA seq 332 aa AA seqDB search
MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVS
GILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGAN
MKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPL
IYALRSQELRKTFKEIICCYPLGGLCDLSSRY
NT seq 999 nt NT seq  +upstreamnt  +downstreamnt
atggtgaactccacccaccgtgggatgcacacttctctgcacctctggaaccgcagcagt
tacagactgcacagcaatgccagtgagtcccttggaaaaggctactctgatggagggtgc
tacgagcaactttttgtctctcctgaggtgtttgtgactctgggtgtcatcagcttgttg
gagaatatcttagtgattgtggcaatagccaagaacaagaatctgcattcacccatgtac
tttttcatctgcagcttggctgtggctgatatgctggtgagcgtttcaaatggatcagaa
accattgtcatcaccctattaaacagtacagatacggatgcacagagtttcacagtgaat
attgataatgtcattgactcggtgatctgtagctccttgcttgcatccatttgcagcctg
ctttcaattgcagtggacaggtactttactatcttctatgctctccagtaccataacatt
atgacagttaagcgggttgggatcatcataagttgtatctgggcagcttgcacggtttca
ggcattttgttcatcatttactcagatagtagtgctgtcatcatctgcctcatcaccatg
ttcttcaccatgctggctctcatggcttctctctatgtccacatgttcctgatggccagg
cttcacattaagaggattgctgtcctccccggcactggtgccatccgccaaggtgccaat
atgaagggagcgattaccttgaccatcctgattggcgtctttgttgtctgctgggcccca
ttcttcctccacttaatattctacatctcttgtcctcagaatccatattgtgtgtgcttc
atgtctcactttaacttgtatctcatactgatcatgtgtaattcaatcatcgatcctctg
atttatgcactccggagtcaagaactgaggaaaaccttcaaagagatcatctgttgctat
cccctgggaggcctttgtgacttgtctagcagatattaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Drug (5)   
   KEGG DRUG (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (11)   
   RefSeq(nuc) (1)   
   GenBank (5)   
   EMBL (5)   
Protein domain (4)   
   Pfam (4)   
All databases (44)   

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