KEGG   Homo sapiens (human): 4179
Entry
4179              CDS       T01001                                 
Symbol
CD46, AHUS2, MCP, MIC10, TLX, TRA2.10
Name
(RefSeq) CD46 molecule
  KO
K04007  membrane cofactor protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa03267  Virion - Adenovirus
hsa04610  Complement and coagulation cascades
hsa05162  Measles
Network
nt06513  Complement cascade
  Element
N01496  Alternative pathway of complement cascade, C3b breakdown
Disease
H01434  Atypical hemolytic uremic syndrome
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03267 Virion - Adenovirus
    4179 (CD46)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    4179 (CD46)
 09160 Human Diseases
  09172 Infectious disease: viral
   05162 Measles
    4179 (CD46)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    4179 (CD46)
   04090 CD molecules [BR:hsa04090]
    4179 (CD46)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   4179 (CD46)
CD molecules [BR:hsa04090]
 Proteins
  4179 (CD46)
SSDB
Motif
Pfam: Sushi Syndecan ECSCR
Other DBs
NCBI-GeneID: 4179
NCBI-ProteinID: NP_002380
OMIM: 120920
HGNC: 6953
Ensembl: ENSG00000117335
Pharos: P15529(Tbio)
UniProt: P15529
Structure
Position
1:207752038..207795516
AA seq 392 aa
MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERV
DYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFG
YQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEV
FEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQIS
GFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVLPPSSTKPPALSHS
VSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAV
ICVVPYRYLQRRKKKGTYLTDETHREVKFTSL
NT seq 1179 nt   +upstreamnt  +downstreamnt
atggagcctcccggccgccgcgagtgtccctttccttcctggcgctttcctgggttgctt
ctggcggccatggtgttgctgctgtactccttctccgatgcctgtgaggagccaccaaca
tttgaagctatggagctcattggtaaaccaaaaccctactatgagattggtgaacgagta
gattataagtgtaaaaaaggatacttctatatacctcctcttgccacccatactatttgt
gatcggaatcatacatggctacctgtctcagatgacgcctgttatagagaaacatgtcca
tatatacgggatcctttaaatggccaagcagtccctgcaaatgggacttacgagtttggt
tatcagatgcactttatttgtaatgagggttattacttaattggtgaagaaattctatat
tgtgaacttaaaggatcagtagcaatttggagcggtaagcccccaatatgtgaaaaggtt
ttgtgtacaccacctccaaaaataaaaaatggaaaacacacctttagtgaagtagaagta
tttgagtatcttgatgcagtaacttatagttgtgatcctgcacctggaccagatccattt
tcacttattggagagagcacgatttattgtggtgacaattcagtgtggagtcgtgctgct
ccagagtgtaaagtggtcaaatgtcgatttccagtagtcgaaaatggaaaacagatatca
ggatttggaaaaaaattttactacaaagcaacagttatgtttgaatgcgataagggtttt
tacctcgatggcagcgacacaattgtctgtgacagtaacagtacttgggatcccccagtt
ccaaagtgtcttaaagtgctgcctccatctagtacaaaacctccagctttgagtcattca
gtgtcgacttcttccactacaaaatctccagcgtccagtgcctcaggtcctaggcctact
tacaagcctccagtctcaaattatccaggatatcctaaacctgaggaaggaatacttgac
agtttggatgtttgggtcattgctgtgattgttattgccatagttgttggagttgcagta
atttgtgttgtcccgtacagatatcttcaaaggaggaagaagaaaggcacatacctaact
gatgagacccacagagaagtaaaatttacttctctctga

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