KEGG   Homo sapiens (human): 4200
Entry
4200              CDS       T01001                                 

Gene name
ME2, ODS1
Definition
(RefSeq) malic enzyme 2
  KO
K00027  malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00620  Pyruvate metabolism
hsa01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    4200 (ME2)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.38  malate dehydrogenase (oxaloacetate-decarboxylating)
     4200 (ME2)
SSDB
Motif
Pfam: Malic_M malic
Other DBs
NCBI-GeneID: 4200
NCBI-ProteinID: NP_002387
OMIM: 154270
HGNC: 6984
Ensembl: ENSG00000082212
Vega: OTTHUMG00000132694
Pharos: P23368(Tbio)
UniProt: P23368
Structure
PDB: 

Position
18q21.2
AA seq 584 aa
MLSRLRVVSTTCTLACRHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIET
QDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLAC
SQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIP
VGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFYMGLYQKRDRTQQYDDLIDEFMK
AITDRYGRNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVISK
PISEHKILFLGAGEAALGIANLIVMSMVENGLSEQEAQKKIWMFDKYGLLVKGRKAKIDS
YQEPFTHSAPESIPDTFEDAVNILKPSTIIGVAGAGRLFTPDVIRAMASINERPVIFALS
NPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLTDGRVFTPGQGNNVYIFPGVALAVIL
CNTRHISDSVFLEAAKALTSQLTDEELAQGRLYPPLANIQEVSINIAIKVTEYLYANKMA
FRYPEPEDKAKYVKERTWRSEYDSLLPDVYEWPESASSPPVITE
NT seq 1755 nt   +upstreamnt  +downstreamnt
atgttgtcccggttaagagtagtttccaccacttgtactttggcatgtcgacatttgcac
ataaaagaaaaaggcaagccacttatgctgaacccaagaacaaacaagggaatggcattt
actttacaagaacgacaaatgcttggtcttcaaggacttctacctcccaaaatagagaca
caagatattcaagccttacgatttcatagaaacttgaagaaaatgactagccctttggaa
aaatatatctacataatgggaatacaagaaagaaatgagaaattgttttatagaatactg
caagatgacattgagagtttaatgccaattgtatatacaccgacggttggtcttgcctgc
tcccagtatggacacatctttagaagacctaagggattatttatttcgatctcagacaga
ggtcatgttagatcaattgtggataactggccagaaaatcatgttaaggctgttgtagtg
actgatggagagagaattctgggtcttggagatctgggtgtctatggaatgggaattcca
gtaggaaaactttgtttgtatacagcttgtgcaggaatacggcctgatagatgcctgcca
gtgtgtattgatgtgggaactgataatatcgcactcttaaaagacccattttacatgggc
ttgtaccagaaacgagatcgcacacaacagtatgatgacctgattgatgagtttatgaaa
gctattactgacagatatggccggaacacactcattcagttcgaagactttggaaatcat
aatgcattcaggttcttgagaaagtaccgagaaaaatattgtactttcaatgatgatatt
caagggacagctgcagtagctctagcaggtcttcttgcagcacaaaaagttattagtaaa
ccaatctccgaacacaaaatcttattccttggagcaggagaggctgctcttggaattgca
aatcttatagttatgtctatggtagaaaatggcctgtcagaacaagaggcacaaaagaaa
atctggatgtttgacaagtatggtttattagttaagggacggaaagcaaaaatagatagt
tatcaggaaccatttactcactcagccccagagagcatacctgatacttttgaagatgca
gtgaatatactgaagccttcaactataattggagttgcaggtgctggccgtcttttcact
cctgatgtaatcagagccatggcctctatcaatgaaaggcctgtaatatttgcattaagt
aatcctacagcacaggcagagtgcacggctgaagaagcatatacacttacagagggcagg
tgtttgtttgccagtggcagtccatttgggccagtgaaacttacagatgggcgagtcttt
acaccaggtcaaggaaacaatgtttatatttttccaggtgtggctttagctgttattctc
tgtaacacccggcatattagtgacagtgttttcctagaagctgcaaaggccctgacaagc
caattgacagatgaagagctagcccaagggagactttacccaccgcttgctaatattcag
gaagtttctattaacattgctattaaagttacagaatacctatatgctaataaaatggct
ttccgatacccagaacctgaagacaaggccaaatatgttaaagaaagaacatggcggagt
gaatatgattccctgctgccagatgtgtatgaatggccagaatctgcatcaagccctcct
gtgataacagaatag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (21)   
   RefSeq(nuc) (3)   
   GenBank (9)   
   EMBL (9)   
Protein domain (2)   
   Pfam (2)   
All databases (58)   

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