KEGG   Homo sapiens (human): 4200
Entry
4200              CDS       T01001                                 
Symbol
ME2, ODS1
Name
(RefSeq) malic enzyme 2
  KO
K00027  malate dehydrogenase (oxaloacetate-decarboxylating) [EC:1.1.1.38]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00620  Pyruvate metabolism
hsa01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    4200 (ME2)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.38  malate dehydrogenase (oxaloacetate-decarboxylating)
     4200 (ME2)
SSDB
Motif
Pfam: Malic_M malic
Other DBs
NCBI-GeneID: 4200
NCBI-ProteinID: NP_002387
OMIM: 154270
HGNC: 6984
Ensembl: ENSG00000082212
UniProt: P23368
Structure
Position
18:50879118..50954257
AA seq 584 aa
MLSRLRVVSTTCTLACRHLHIKEKGKPLMLNPRTNKGMAFTLQERQMLGLQGLLPPKIET
QDIQALRFHRNLKKMTSPLEKYIYIMGIQERNEKLFYRILQDDIESLMPIVYTPTVGLAC
SQYGHIFRRPKGLFISISDRGHVRSIVDNWPENHVKAVVVTDGERILGLGDLGVYGMGIP
VGKLCLYTACAGIRPDRCLPVCIDVGTDNIALLKDPFYMGLYQKRDRTQQYDDLIDEFMK
AITDRYGRNTLIQFEDFGNHNAFRFLRKYREKYCTFNDDIQGTAAVALAGLLAAQKVISK
PISEHKILFLGAGEAALGIANLIVMSMVENGLSEQEAQKKIWMFDKYGLLVKGRKAKIDS
YQEPFTHSAPESIPDTFEDAVNILKPSTIIGVAGAGRLFTPDVIRAMASINERPVIFALS
NPTAQAECTAEEAYTLTEGRCLFASGSPFGPVKLTDGRVFTPGQGNNVYIFPGVALAVIL
CNTRHISDSVFLEAAKALTSQLTDEELAQGRLYPPLANIQEVSINIAIKVTEYLYANKMA
FRYPEPEDKAKYVKERTWRSEYDSLLPDVYEWPESASSPPVITE
NT seq 1755 nt   +upstreamnt  +downstreamnt
atgttgtcccggttaagagtagtttccaccacttgtactttggcatgtcgacatttgcac
ataaaagaaaaaggcaagccacttatgctgaacccaagaacaaacaagggaatggcattt
actttacaagaacgacaaatgcttggtcttcaaggacttctacctcccaaaatagagaca
caagatattcaagccttacgatttcatagaaacttgaagaaaatgactagccctttggaa
aaatatatctacataatgggaatacaagaaagaaatgagaaattgttttatagaatactg
caagatgacattgagagtttaatgccaattgtatatacaccgacggttggtcttgcctgc
tcccagtatggacacatctttagaagacctaagggattatttatttcgatctcagacaga
ggtcatgttagatcaattgtggataactggccagaaaatcatgttaaggctgttgtagtg
actgatggagagagaattctgggtcttggagatctgggtgtctatggaatgggaattcca
gtaggaaaactttgtttgtatacagcttgtgcaggaatacggcctgatagatgcctgcca
gtgtgtattgatgtgggaactgataatatcgcactcttaaaagacccattttacatgggc
ttgtaccagaaacgagatcgcacacaacagtatgatgacctgattgatgagtttatgaaa
gctattactgacagatatggccggaacacactcattcagttcgaagactttggaaatcat
aatgcattcaggttcttgagaaagtaccgagaaaaatattgtactttcaatgatgatatt
caagggacagctgcagtagctctagcaggtcttcttgcagcacaaaaagttattagtaaa
ccaatctccgaacacaaaatcttattccttggagcaggagaggctgctcttggaattgca
aatcttatagttatgtctatggtagaaaatggcctgtcagaacaagaggcacaaaagaaa
atctggatgtttgacaagtatggtttattagttaagggacggaaagcaaaaatagatagt
tatcaggaaccatttactcactcagccccagagagcatacctgatacttttgaagatgca
gtgaatatactgaagccttcaactataattggagttgcaggtgctggccgtcttttcact
cctgatgtaatcagagccatggcctctatcaatgaaaggcctgtaatatttgcattaagt
aatcctacagcacaggcagagtgcacggctgaagaagcatatacacttacagagggcagg
tgtttgtttgccagtggcagtccatttgggccagtgaaacttacagatgggcgagtcttt
acaccaggtcaaggaaacaatgtttatatttttccaggtgtggctttagctgttattctc
tgtaacacccggcatattagtgacagtgttttcctagaagctgcaaaggccctgacaagc
caattgacagatgaagagctagcccaagggagactttacccaccgcttgctaatattcag
gaagtttctattaacattgctattaaagttacagaatacctatatgctaataaaatggct
ttccgatacccagaacctgaagacaaggccaaatatgttaaagaaagaacatggcggagt
gaatatgattccctgctgccagatgtgtatgaatggccagaatctgcatcaagccctcct
gtgataacagaatag

  All links  
Disease (1)   
   OMIM (1)   
Gene (14)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (21)   
   RefSeq(nuc) (3)   
   GenBank (9)   
   EMBL (9)   
3D Structure (16)   
   PDB (16)   
Protein domain (2)   
   Pfam (2)   
All databases (58)   

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