KEGG   Homo sapiens (human): 4300Help
Entry
4300              CDS       T01001                                 

Gene name
MLLT3, AF9, YEATS3
Definition
(RefSeq) MLLT3 super elongation complex subunit
  KO
K15187  YEATS domain-containing protein 1/3
Organism
hsa  Homo sapiens (human)
Pathway
hsa05202  Transcriptional misregulation in cancer
Network
nt06240  Transcription
  Element
N00119  MLL-AF4 fusion to transcriptional activation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    4300 (MLLT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    4300 (MLLT3)
   03036 Chromosome and associated proteins [BR:hsa03036]
    4300 (MLLT3)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Super elongation complex (SEC)
     4300 (MLLT3)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HMT complexes
    Dot1-containing complex
     4300 (MLLT3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: AHD YEATS BET
Motif
Other DBs
NCBI-GeneID: 4300
NCBI-ProteinID: NP_004520
OMIM: 159558
HGNC: 7136
Ensembl: ENSG00000171843
Vega: OTTHUMG00000019650
Pharos: P42568(Tbio)
UniProt: P42568 A0A0S2Z448
Structure
PDB: 

Position
9p21.3
AA seq 568 aa AA seqDB search
MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFP
RPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCE
KLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS
SSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENK
PLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKK
SSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVD
PNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESD
EVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILE
VKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITN
TTFDFDLCSLDKTTVRKLQSYLETSGTS
NT seq 1707 nt NT seq  +upstreamnt  +downstreamnt
atggctagctcgtgtgccgtgcaggtgaagctggagctggggcaccgcgcccaggtgagg
aaaaaacccaccgtggagggcttcacccacgactggatggtgttcgtacgcggtccggag
cacagtaacatacagcactttgtggagaaagtcgtcttccacttgcacgaaagctttcct
aggccaaaaagagtgtgcaaagatccaccttacaaagtagaagaatctgggtatgctggt
ttcattttgccaattgaagtttattttaaaaacaaggaagaacctaggaaagtccgcttt
gattatgacttattcctgcatcttgaaggccatccaccagtgaatcacctccgctgtgaa
aagctaactttcaacaaccccacagaggactttaggagaaagttgctgaaggcaggaggg
gaccctaataggagtattcataccagcagcagcagcagcagcagcagtagcagcagcagc
agcagcagcagcagcagcagtagcagcagcagcagcagcagcagcagcagcagtagcagc
agcagtagcagcagcagcagcagcagtagtaccagtttttcaaagcctcacaaattaatg
aaggagcacaaggaaaaaccttctaaagactccagagaacataaaagtgccttcaaagaa
ccttccagggatcacaacaaatcttccaaagaatcctctaagaaacccaaagaaaataaa
ccactgaaagaagagaaaatagttcctaagatggccttcaaggaacctaaacccatgtca
aaagagccaaaaccagatagtaacttactcaccatcaccagtggacaagataagaaggct
cctagtaaaaggccgcccatttcagattctgaagaactctcagccaaaaaaaggaaaaag
agtagctcagaggctttatttaaaagtttttctagcgcaccaccactgatactcacttgt
tctgctgacaaaaaacagataaaagataaatctcatgtcaagatgggaaaggtcaaaatt
gaaagtgagacatcagagaagaagaaatcaacgttaccgccatttgatgatattgtggat
cccaatgattcagatgtggaggagaatatatcctctaaatctgattctgaacaacccagt
cctgccagctccagctccagctccagctccagcttcacaccatcccagaccaggcaacaa
ggtcctttgaggtctataatgaaagatctgcattctgatgacaatgaggaggaatcagat
gaagtggaggataacgacaatgactctgaaatggagaggcctgtaaatagaggaggcagc
cgaagtcgcagagttagcttaagtgatggcagcgatagtgaaagcagttctgcttcttca
cccctacatcacgaacctccaccacccttactaaaaaccaacaacaaccagattcttgaa
gtgaaaagtccaataaagcaaagcaaatcagataagcaaataaagaatggtgaatgtgac
aaggcatacctagatgaactggtagagcttcacagaaggttaatgacattgagagaaaga
cacattctgcagcagatcgtgaaccttatagaagaaactggacactttcatatcacaaac
acaacatttgattttgatctttgctcgctggacaaaaccacagtccgtaaactacagagt
tacctggaaacatctggaacatcctga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Network (1)   
   KEGG NETWORK (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (36)   
   RefSeq(nuc) (4)   
   GenBank (16)   
   EMBL (16)   
Protein domain (3)   
   Pfam (3)   
All databases (80)   

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