KEGG   Homo sapiens (human): 4300
Entry
4300              CDS       T01001                                 
Symbol
MLLT3, AF9, YEATS3
Name
(RefSeq) MLLT3 super elongation complex subunit
  KO
K15187  YEATS domain-containing protein 1/3
Organism
hsa  Homo sapiens (human)
Pathway
hsa03250  Viral life cycle - HIV-1
hsa05202  Transcriptional misregulation in cancer
Network
nt06240  Transcription (cancer)
  Element
N00119  MLL-AF4 fusion to transcriptional activation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09125 Information processing in viruses
   03250 Viral life cycle - HIV-1
    4300 (MLLT3)
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    4300 (MLLT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    4300 (MLLT3)
   03036 Chromosome and associated proteins [BR:hsa03036]
    4300 (MLLT3)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Super elongation complex (SEC)
     4300 (MLLT3)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HMT complexes
    Dot1-containing complex
     4300 (MLLT3)
SSDB
Motif
Pfam: AHD YEATS pYEATS BET
Other DBs
NCBI-GeneID: 4300
NCBI-ProteinID: NP_004520
OMIM: 159558
HGNC: 7136
Ensembl: ENSG00000171843
UniProt: P42568 A0A0S2Z448
Structure
Position
9:complement(20341669..20622499)
AA seq 568 aa
MASSCAVQVKLELGHRAQVRKKPTVEGFTHDWMVFVRGPEHSNIQHFVEKVVFHLHESFP
RPKRVCKDPPYKVEESGYAGFILPIEVYFKNKEEPRKVRFDYDLFLHLEGHPPVNHLRCE
KLTFNNPTEDFRRKLLKAGGDPNRSIHTSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS
SSSSSSSSSSTSFSKPHKLMKEHKEKPSKDSREHKSAFKEPSRDHNKSSKESSKKPKENK
PLKEEKIVPKMAFKEPKPMSKEPKPDSNLLTITSGQDKKAPSKRPPISDSEELSAKKRKK
SSSEALFKSFSSAPPLILTCSADKKQIKDKSHVKMGKVKIESETSEKKKSTLPPFDDIVD
PNDSDVEENISSKSDSEQPSPASSSSSSSSSFTPSQTRQQGPLRSIMKDLHSDDNEEESD
EVEDNDNDSEMERPVNRGGSRSRRVSLSDGSDSESSSASSPLHHEPPPPLLKTNNNQILE
VKSPIKQSKSDKQIKNGECDKAYLDELVELHRRLMTLRERHILQQIVNLIEETGHFHITN
TTFDFDLCSLDKTTVRKLQSYLETSGTS
NT seq 1707 nt   +upstreamnt  +downstreamnt
atggctagctcgtgtgccgtgcaggtgaagctggagctggggcaccgcgcccaggtgagg
aaaaaacccaccgtggagggcttcacccacgactggatggtgttcgtacgcggtccggag
cacagtaacatacagcactttgtggagaaagtcgtcttccacttgcacgaaagctttcct
aggccaaaaagagtgtgcaaagatccaccttacaaagtagaagaatctgggtatgctggt
ttcattttgccaattgaagtttattttaaaaacaaggaagaacctaggaaagtccgcttt
gattatgacttattcctgcatcttgaaggccatccaccagtgaatcacctccgctgtgaa
aagctaactttcaacaaccccacagaggactttaggagaaagttgctgaaggcaggaggg
gaccctaataggagtattcataccagcagcagcagcagcagcagcagtagcagcagcagc
agcagcagcagcagcagcagtagcagcagcagcagcagcagcagcagcagcagtagcagc
agcagtagcagcagcagcagcagcagtagtaccagtttttcaaagcctcacaaattaatg
aaggagcacaaggaaaaaccttctaaagactccagagaacataaaagtgccttcaaagaa
ccttccagggatcacaacaaatcttccaaagaatcctctaagaaacccaaagaaaataaa
ccactgaaagaagagaaaatagttcctaagatggccttcaaggaacctaaacccatgtca
aaagagccaaaaccagatagtaacttactcaccatcaccagtggacaagataagaaggct
cctagtaaaaggccgcccatttcagattctgaagaactctcagccaaaaaaaggaaaaag
agtagctcagaggctttatttaaaagtttttctagcgcaccaccactgatactcacttgt
tctgctgacaaaaaacagataaaagataaatctcatgtcaagatgggaaaggtcaaaatt
gaaagtgagacatcagagaagaagaaatcaacgttaccgccatttgatgatattgtggat
cccaatgattcagatgtggaggagaatatatcctctaaatctgattctgaacaacccagt
cctgccagctccagctccagctccagctccagcttcacaccatcccagaccaggcaacaa
ggtcctttgaggtctataatgaaagatctgcattctgatgacaatgaggaggaatcagat
gaagtggaggataacgacaatgactctgaaatggagaggcctgtaaatagaggaggcagc
cgaagtcgcagagttagcttaagtgatggcagcgatagtgaaagcagttctgcttcttca
cccctacatcacgaacctccaccacccttactaaaaaccaacaacaaccagattcttgaa
gtgaaaagtccaataaagcaaagcaaatcagataagcaaataaagaatggtgaatgtgac
aaggcatacctagatgaactggtagagcttcacagaaggttaatgacattgagagaaaga
cacattctgcagcagatcgtgaaccttatagaagaaactggacactttcatatcacaaac
acaacatttgattttgatctttgctcgctggacaaaaccacagtccgtaaactacagagt
tacctggaaacatctggaacatcctga

  All links  
Disease (1)   
   OMIM (1)   
Gene (24)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (34)   
   RefSeq(nuc) (2)   
   GenBank (16)   
   EMBL (16)   
3D Structure (24)   
   PDB (24)   
Protein domain (4)   
   Pfam (4)   
All databases (92)   

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