KEGG   Homo sapiens (human): 438
Entry
438               CDS       T01001                                 
Symbol
ASMT, ASMTY, HIOMT, HIOMTY
Name
(RefSeq) acetylserotonin O-methyltransferase
  KO
K00543  acetylserotonin O-methyltransferase [EC:2.1.1.4]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00380  Tryptophan metabolism
hsa01100  Metabolic pathways
Module
hsa_M00037  Melatonin biosynthesis, animals, tryptophan => serotonin => melatonin
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    438 (ASMT)
Enzymes [BR:hsa01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.4  acetylserotonin O-methyltransferase
     438 (ASMT)
SSDB
Motif
Pfam: Methyltransf_2 Dimerisation Methyltransf_12 Methyltransf_25 Methyltransf_31
Other DBs
NCBI-GeneID: 438
NCBI-ProteinID: NP_001164509
OMIM: 300015 402500
HGNC: 750
Ensembl: ENSG00000196433 ENSG00000292336
UniProt: P46597
Structure
Position
X:1615059..1643081, Y:1615059..1643081
AA seq 373 aa
MGSSEDQAYRLLNDYANGFMVSQVLFAACELGVFDLLAEAPGPLDVAAVAAGVRASAHGT
ELLLDICVSLKLLKVETRGGKAFYRNTELSSDYLTTVSPTSQCSMLKYMGRTSYRCWGHL
ADAVREGRNQYLETFGVPAEELFTAIYRSEGERLQFMQALQEVWSVNGRSVLTAFDLSVF
PLMCDLGGTWIKLETIILSKLSQGQKTKHRVFSLIGGAGALAKECMSLYPGCKITVFDIP
EVVWTAKQHFSFQEEEQIDFQEGDFFKDPLPEADLYILARVLHDWADGKCSHLLERIYHT
CKPGGGILVIESLLDEDRRGPLLTQLYSLNMLVQTEGQERTPTHYHMLLSSAGFRDFQFK
KTGAIYDAILARK
NT seq 1122 nt   +upstreamnt  +downstreamnt
atgggatcctcagaggaccaggcctatcgcctccttaatgactacgccaacggcttcatg
gtgtcccaggttctcttcgccgcctgcgagctgggcgtgtttgaccttctcgccgaggcc
ccagggcccctggacgtggcggcagtggctgcaggtgtgagggccagcgcccatgggaca
gagctcctgctggacatctgtgtgtccctgaagctgctgaaagtggagacgaggggagga
aaagctttctatcgaaacacagagctgtccagcgactacctgaccacggtcagcccgacg
tcacaatgcagcatgctgaagtacatgggcaggaccagctaccggtgctggggccacctg
gcagacgccgtgagagaaggaaggaaccagtacctggagacgtttggcgttcccgctgaa
gagctttttacggccatctacaggtccgagggcgagcggctacagttcatgcaagctctg
caggaggtctggagcgtcaacgggagaagcgtgctgaccgcctttgacctgtcagtgttc
ccacttatgtgtgaccttggtgggacatggataaagctggaaaccatcattctcagcaaa
ctatcgcaaggacagaaaaccaaacaccgcgtgttctcactcataggtggggctggagct
ctggctaaggaatgcatgtctctgtaccctggatgtaagatcaccgtttttgacatccca
gaagtggtgtggacggcaaagcagcacttctcattccaggaggaagaacagattgacttc
caggaaggggatttcttcaaagaccctcttccggaagctgatctgtacatcctggccagg
gtcctccatgactgggcagacggaaagtgctcacacctgctggagaggatctaccacact
tgcaagccaggtggtggcattctggtaattgaaagcctcctggatgaagacaggcgaggt
cctctgctcacgcagctctactctctgaacatgcttgtgcagacggaagggcaggagagg
acccccacccactaccacatgctcctctcttctgctggcttcagagacttccagtttaag
aaaacaggagccatttatgatgccattttagccaggaaataa

  All links  
Disease (2)   
   OMIM (2)   
Gene (20)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (2)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (22)   
   RefSeq(nuc) (4)   
   GenBank (9)   
   EMBL (9)   
3D Structure (2)   
   PDB (2)   
Protein domain (5)   
   Pfam (5)   
All databases (56)   

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