KEGG   Homo sapiens (human): 4671
Entry
4671              CDS       T01001                                 

Symbol
NAIP, BIRC1, NLRB1, psiNAIP
Name
(RefSeq) NLR family apoptosis inhibitory protein
  KO
K12807  baculoviral IAP repeat-containing protein 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04621  NOD-like receptor signaling pathway
hsa05130  Pathogenic Escherichia coli infection
hsa05131  Shigellosis
hsa05132  Salmonella infection
hsa05134  Legionellosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    4671 (NAIP)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05130 Pathogenic Escherichia coli infection
    4671 (NAIP)
   05132 Salmonella infection
    4671 (NAIP)
   05131 Shigellosis
    4671 (NAIP)
   05134 Legionellosis
    4671 (NAIP)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    4671 (NAIP)
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors [BR:hsa04054]
    4671 (NAIP)
Peptidases and inhibitors [BR:hsa01002]
 Peptidase inhibitors
  Family I32: IAP family
   4671 (NAIP)
Pattern recognition receptors [BR:hsa04054]
 Cytoplasmic pattern recognition receptors
  NOD-like receptors
   4671 (NAIP)
SSDB
Motif
Pfam: BIR NLRC4_HD NACHT NOD2_WH NB-ARC LRR_4 AAA_30 AAA_22 DUF2075 AAA
Other DBs
NCBI-GeneID: 4671
NCBI-ProteinID: NP_001333799
OMIM: 600355
HGNC: 7634
Ensembl: ENSG00000249437
Vega: OTTHUMG00000163318
Pharos: Q13075(Tbio)
UniProt: Q13075
Structure
PDB: 
2VM5

Position
5q13.2
AA seq 1403 aa
MATQQKASDERISQFDHNLLPELSALLGLDAVQLAKELEEEEQKERAKMQKGYNSQMRSE
AKRLKTFVTYEPYSSWIPQEMAAAGFYFTGVKSGIQCFCCSLILFGAGLTRLPIEDHKRF
HPDCGFLLNKDVGNIAKYDIRVKNLKSRLRGGKMRYQEEEARLASFRNWPFYVQGISPCV
LSEAGFVFTGKQDTVQCFSCGGCLGNWEEGDDPWKEHAKWFPKCEFLRSKKSSEEITQYI
QSYKGFVDITGEHFVNSWVQRELPMASAYCNDSIFAYEELRLDSFKDWPRESAVGVAALA
KAGLFYTGIKDIVQCFSCGGCLEKWQEGDDPLDDHTRCFPNCPFLQNMKSSAEVTPDLQS
RGELCELLETTSESNLEDSIAVGPIVPEMAQGEAQWFQEAKNLNEQLRAAYTSASFRHMS
LLDISSDLATDHLLGCDLSIASKHISKPVQEPLVLPEVFGNLNSVMCVEGEAGSGKTVLL
KKIAFLWASGCCPLLNRFQLVFYLSLSSTRPDEGLASIICDQLLEKEGSVTEMCVRNIIQ
QLKNQVLFLLDDYKEICSIPQVIGKLIQKNHLSRTCLLIAVRTNRARDIRRYLETILEIK
AFPFYNTVCILRKLFSHNMTRLRKFMVYFGKNQSLQKIQKTPLFVAAICAHWFQYPFDPS
FDDVAVFKSYMERLSLRNKATAEILKATVSSCGELALKGFFSCCFEFNDDDLAEAGVDED
EDLTMCLMSKFTAQRLRPFYRFLSPAFQEFLAGMRLIELLDSDRQEHQDLGLYHLKQINS
PMMTVSAYNNFLNYVSSLPSTKAGPKIVSHLLHLVDNKESLENISENDDYLKHQPEISLQ
MQLLRGLWQICPQAYFSMVSEHLLVLALKTAYQSNTVAACSPFVLQFLQGRTLTLGALNL
QYFFDHPESLSLLRSIHFPIRGNKTSPRAHFSVLETCFDKSQVPTIDQDYASAFEPMNEW
ERNLAEKEDNVKSYMDMQRRASPDLSTGYWKLSPKQYKIPCLEVDVNDIDVVGQDMLEIL
MTVFSASQRIELHLNHSRGFIESIRPALELSKASVTKCSISKLELSAAEQELLLTLPSLE
SLEVSGTIQSQDQIFPNLDKFLCLKELSVDLEGNINVFSVIPEEFPNFHHMEKLLIQISA
EYDPSKLVKLIQNSPNLHVFHLKCNFFSDFGSLMTMLVSCKKLTEIKFSDSFFQAVPFVA
SLPNFISLKILNLEGQQFPDEETSEKFAYILGSLSNLEELILPTGDGIYRVAKLIIQQCQ
QLHCLRVLSFFKTLNDDSVVEIAKVAISGGFQKLENLKLSINHKITEEGYRNFFQALDNM
PNLQELDISRHFTECIKAQATTVKSLSQCVLRLPRLIRLNMLSWLLDADDIALLNVMKER
HPQSKYLTILQKWILPFSPIIQK
NT seq 4212 nt   +upstreamnt  +downstreamnt
atggccacccagcagaaagcctctgacgagaggatctcccagtttgatcacaatttgctg
ccagagctgtctgctcttctgggcctagatgcagttcagttggcaaaggaactagaagaa
gaggagcagaaggagcgagcaaaaatgcagaaaggctacaactctcaaatgcgcagtgaa
gcaaaaaggttaaagacttttgtgacttatgagccgtacagctcatggataccacaggag
atggcggccgctgggttttacttcactggggtaaaatctgggattcagtgcttctgctgt
agcctaatcctctttggtgccggcctcacgagactccccatagaagaccacaagaggttt
catccagattgtgggttccttttgaacaaggatgttggtaacattgccaagtacgacata
agggtgaagaatctgaagagcaggctgagaggaggtaaaatgaggtaccaagaagaggag
gctagacttgcgtccttcaggaactggccattttatgtccaagggatatccccttgtgtg
ctctcagaggctggctttgtctttacaggtaaacaggacacggtacagtgtttttcctgt
ggtggatgtttaggaaattgggaagaaggagatgatccttggaaggaacatgccaaatgg
ttccccaaatgtgaatttcttcggagtaagaaatcctcagaggaaattacccagtatatt
caaagctacaagggatttgttgacataacgggagaacattttgtgaattcctgggtccag
agagaattacctatggcatcagcttattgcaatgacagcatctttgcttacgaagaacta
cggctggactcttttaaggactggccccgggaatcagctgtgggagttgcagcactggcc
aaagcaggtcttttctacacaggtataaaggacatcgtccagtgcttttcctgtggaggg
tgtttagagaaatggcaggaaggtgatgacccattagacgatcacaccagatgttttccc
aattgtccatttctccaaaatatgaagtcctctgcggaagtgactccagaccttcagagc
cgtggtgaactttgtgaattactggaaaccacaagtgaaagcaatcttgaagattcaata
gcagttggtcctatagtgccagaaatggcacagggtgaagcccagtggtttcaagaggca
aagaatctgaatgagcagctgagagcagcttataccagcgccagtttccgccacatgtct
ttgcttgatatctcttccgatctggccacggaccacttgctgggctgtgatctgtctatt
gcttcaaaacacatcagcaaacctgtgcaagaacctctggtgctgcctgaggtctttggc
aacttgaactctgtcatgtgtgtggagggtgaagctggaagtggaaagacggtcctcctg
aagaaaatagcttttctgtgggcatctggatgctgtcccctgttaaacaggttccagctg
gttttctacctctcccttagttccaccagaccagacgaggggctggccagtatcatctgt
gaccagctcctagagaaagaaggatctgttactgaaatgtgcgtgaggaacattatccag
cagttaaagaatcaggtcttattccttttagatgactacaaagaaatatgttcaatccct
caagtcataggaaaactgattcaaaaaaaccacttatcccggacctgcctattgattgct
gtccgtacaaacagggccagggacatccgccgatacctagagaccattctagagatcaaa
gcatttcccttttataatactgtctgtatattacggaagctcttttcacataatatgact
cgtctgcgaaagtttatggtttactttggaaagaaccaaagtttgcagaagatacagaaa
actcctctctttgtggcggcgatctgtgctcattggtttcagtatccttttgacccatcc
tttgatgatgtggctgttttcaagtcctatatggaacgcctttccttaaggaacaaagcg
acagctgaaattctcaaagcaactgtgtcctcctgtggtgagctggccttgaaagggttt
ttttcatgttgctttgagtttaatgatgatgatctcgcagaagcaggggttgatgaagat
gaagatctaaccatgtgcttgatgagcaaatttacagcccagagactaagaccattctac
cggtttttaagtcctgccttccaagaatttcttgcggggatgaggctgattgaactcctg
gattcagataggcaggaacatcaagatttgggactgtatcatttgaaacaaatcaactca
cccatgatgactgtaagcgcctacaacaattttttgaactatgtctccagcctcccttca
acaaaagcagggcccaaaattgtgtctcatttgctccatttagtggataacaaagagtca
ttggagaatatatctgaaaatgatgactacttaaagcaccagccagaaatttcactgcag
atgcagttacttaggggattgtggcaaatttgtccacaagcttacttttcaatggtttca
gaacatttactggttcttgccctgaaaactgcttatcaaagcaacactgttgctgcgtgt
tctccatttgttttgcaattccttcaagggagaacactgactttgggtgcgcttaactta
cagtactttttcgaccacccagaaagcttgtcattgttgaggagcatccacttcccaata
cgaggaaataagacatcacccagagcacatttttcagttctggaaacatgttttgacaaa
tcacaggtgccaactatagatcaggactatgcttctgcctttgaacctatgaatgaatgg
gagcgaaatttagctgaaaaagaggataatgtaaagagctatatggatatgcagcgcagg
gcatcaccagaccttagtactggctattggaaactttctccaaagcagtacaagattccc
tgtctagaagtcgatgtgaatgatattgatgttgtaggccaggatatgcttgagattcta
atgacagttttctcagcttcacagcgcatcgaactccatttaaaccacagcagaggcttt
atagaaagcatccgcccagctcttgagctgtctaaggcctctgtcaccaagtgctccata
agcaagttggaactcagcgcagccgaacaggaactgcttctcaccctgccttccctggaa
tctcttgaagtctcagggacaatccagtcacaagaccaaatctttcctaatctggataag
ttcctgtgcctgaaagaactgtctgtggatctggagggcaatataaatgttttttcagtc
attcctgaagaatttccaaacttccaccatatggagaaattattgatccaaatttcagct
gagtatgatccttccaaactagtaaaattaattcaaaattctccaaaccttcatgttttc
catctgaagtgtaacttcttttcggattttgggtctctcatgactatgcttgtttcctgt
aagaaactcacagaaattaagttttcggattcattttttcaagccgtcccatttgttgcc
agtttgccaaattttatttctctgaagatattaaatcttgaaggccagcaatttcctgat
gaggaaacatcagaaaaatttgcctacattttaggttctcttagtaacctggaagaattg
atccttcctactggggatggaatttatcgagtggccaaactgatcatccagcagtgtcag
cagcttcattgtctccgagtcctctcatttttcaagactttgaatgatgacagcgtggtg
gaaattgccaaagtagcaatcagtggaggtttccagaaacttgagaacctaaagctttca
atcaatcacaagattacagaggaaggatacagaaatttctttcaagcactggacaacatg
ccaaacttgcaggagttggacatctccaggcatttcacagagtgtatcaaagctcaggcc
acaacagtcaagtctttgagtcaatgtgtgttacgactaccaaggctcattagactgaac
atgttaagttggctcttggatgcagatgatattgcattgcttaatgtcatgaaagaaaga
catcctcaatctaagtacttaactattctccagaaatggatactgccgttctctccaatc
attcagaaataa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (5)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (34)   
   KEGG ORTHOLOGY (1)   
   RefGene (26)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (23)   
   RefSeq(nuc) (3)   
   GenBank (10)   
   EMBL (10)   
Protein domain (10)   
   Pfam (10)   
All databases (82)   

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