KEGG   Homo sapiens (human): 4706
Entry
4706              CDS       T01001                                 
Symbol
NDUFAB1, ACP, ACP1, FASN2A, SDAP
Name
(RefSeq) NADH:ubiquinone oxidoreductase subunit AB1
  KO
K03955  NADH dehydrogenase (ubiquinone) 1 alpha/beta subcomplex 1, acyl-carrier protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa00190  Oxidative phosphorylation
hsa01100  Metabolic pathways
hsa04714  Thermogenesis
hsa04723  Retrograde endocannabinoid signaling
hsa04932  Non-alcoholic fatty liver disease
hsa05010  Alzheimer disease
hsa05012  Parkinson disease
hsa05014  Amyotrophic lateral sclerosis
hsa05016  Huntington disease
hsa05020  Prion disease
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05208  Chemical carcinogenesis - reactive oxygen species
hsa05415  Diabetic cardiomyopathy
Module
hsa_M00146  NADH dehydrogenase (ubiquinone) 1 alpha subcomplex
hsa_M00873  Fatty acid biosynthesis in mitochondria, animals
Network
nt06460  Alzheimer disease
nt06463  Parkinson disease
nt06464  Amyotrophic lateral sclerosis
nt06466  Pathways of neurodegeneration
  Element
N00995  Electron transfer in Complex I
N00997  Mutation-caused aberrant Abeta to electron transfer in Complex I
N01042  Mutation-caused aberrant SNCA to electron transfer in Complex I
N01043  Mutation-inactivated PINK1 to electron transfer in Complex I
N01044  MPP+ to electron transfer in Complex I
N01045  Rotenone to electron transfer in Complex I
N01136  Mutation-caused aberrant TDP43 to electron transfer in Complex I
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09102 Energy metabolism
   00190 Oxidative phosphorylation
    4706 (NDUFAB1)
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    4706 (NDUFAB1)
 09150 Organismal Systems
  09156 Nervous system
   04723 Retrograde endocannabinoid signaling
    4706 (NDUFAB1)
  09159 Environmental adaptation
   04714 Thermogenesis
    4706 (NDUFAB1)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    4706 (NDUFAB1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    4706 (NDUFAB1)
   05012 Parkinson disease
    4706 (NDUFAB1)
   05014 Amyotrophic lateral sclerosis
    4706 (NDUFAB1)
   05016 Huntington disease
    4706 (NDUFAB1)
   05020 Prion disease
    4706 (NDUFAB1)
   05022 Pathways of neurodegeneration - multiple diseases
    4706 (NDUFAB1)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    4706 (NDUFAB1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    4706 (NDUFAB1)
SSDB
Motif
Pfam: PP-binding PP-binding_2 DUF7080 MinE
Other DBs
NCBI-GeneID: 4706
NCBI-ProteinID: NP_004994
OMIM: 603836
HGNC: 7694
Ensembl: ENSG00000004779
UniProt: O14561
Structure
Position
16:complement(23581014..23596316)
AA seq 156 aa
MASRVLSAYVSRLPAAFAPLPRVRMLAVARPLSTALCSAGTQTRLGTLQPALVLAQVPGR
VTQLCRQYSDMPPLTLEGIQDRVLYVLKLYDKIDPEKLSVNSHFMKDLGLDSLDQVEIIM
AMEDEFGFEIPDIDAEKLMCPQEIVDYIADKKDVYE
NT seq 471 nt   +upstreamnt  +downstreamnt
atggcgtctcgtgtcctttcagcctatgtcagccgcctgcccgcggcctttgcgccgctg
ccccgggtccggatgctggccgtggcccggcctctcagcaccgctctctgctccgcgggg
acccagacgaggctcgggactttgcagccggccttagtgctcgcgcaggttcctggtaga
gttacacagttgtgccgccagtatagcgacatgcctcctttgacgttagagggcatccag
gaccgtgttctttacgtattgaaactctatgacaagattgacccagagaagctttcagta
aattctcattttatgaaagacctgggcttagacagtttggaccaagtggagattatcatg
gccatggaagacgaatttgggtttgaaattcctgatatagatgctgaaaagttaatgtgt
ccacaagaaattgtagattacattgcagataagaaggatgtatatgaataa

  All links  
Disease (1)   
   OMIM (1)   
Gene (25)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (16)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (15)   
   RefSeq(nuc) (3)   
   GenBank (6)   
   EMBL (6)   
3D Structure (38)   
   PDB (38)   
Protein domain (4)   
   Pfam (4)   
All databases (88)   

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