KEGG   Homo sapiens (human): 4849
Entry
4849              CDS       T01001                                 
Symbol
CNOT3, IDDSADF, LENG2, NOT3, NOT3H
Name
(RefSeq) CCR4-NOT transcription complex subunit 3
  KO
K12580  CCR4-NOT transcription complex subunit 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa03018  RNA degradation
Disease
H02371  Intellectual developmental disorder with autism and speech delay
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    4849 (CNOT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    4849 (CNOT3)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     4849 (CNOT3)
  mRNA degradation factors
   3'-5' decay
    Ccr4-NOT complex
     4849 (CNOT3)
SSDB
Motif
Pfam: Not3 NOT2_3_5
Other DBs
NCBI-GeneID: 4849
NCBI-ProteinID: NP_055331
OMIM: 604910
HGNC: 7879
Ensembl: ENSG00000088038
Pharos: O75175(Tbio)
UniProt: O75175 A0A024R4R3
Structure
Position
19:54137762..54155681
AA seq 753 aa
MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD
QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE
KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQDRIEGLKRHIEKHRYHV
RMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVA
TSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSP
AKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPA
PSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGA
GKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGA
GGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPL
SSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVC
PLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTV
EFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEFE
QGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ
NT seq 2262 nt   +upstreamnt  +downstreamnt
atggcggacaagcgcaaactccaaggtgagattgatcgctgcctcaagaaggtgtccgag
ggcgtggagcagtttgaagatatttggcagaagctccacaatgcagccaacgcgaaccag
aaagaaaagtatgaggctgacctaaagaaggagattaagaagctacaacggctgagggac
caaatcaagacatgggtagcgtccaacgagatcaaggacaagaggcagcttatagacaac
cgcaagctcattgagacgcaaatggaacggttcaaagttgtggaacgagagaccaaaacc
aaagcttacagcaaagagggcctgggcctggcccagaaggtagatcctgcccagaaggag
aaggaagaggttggccagtggctcacgaataccatcgacacgctcaacatgcaggtggac
cagtttgagagtgaagtggagtcactgtcagtgcagacacgcaagaagaagggcgacaag
gataagcaggaccggattgagggcttgaagcggcacatcgagaagcaccgctaccacgtg
cgcatgctagagaccatcctgcgcatgctggacaatgactccatcctcgttgacgccatc
cgcaagatcaaggacgacgttgagtactatgttgactcatcccaggaccccgacttcgag
gagaacgagtttctctacgatgacctggacctcgaggacattccacaggcgctggtcgcc
acctccccccccagccacagccacatggaggatgagatcttcaaccagtccagcagcacg
cccacctcaaccacctccagctctcccatcccgcccagcccagccaactgtaccacggaa
aactctgaagatgataagaagaggggacgttccacagacagtgaagtcagccagtctcca
gccaaaaacggctccaagcctgtccacagcaaccagcaccctcagtccccagctgtgccg
cccacctacccctccggccccccgcctgctgcctctgccttgagcaccactcctggcaac
aatggggtccccgcccccgcagcacccccaagtgccctgggccccaaggccagtccagct
cccagccacaactcgggcacccctgctccctatgcccaggctgtggccccaccagctccc
agtgggcccagcacgacccagccccggccccccagcgtccagcctagcggaggcggaggc
ggcggcagcggaggcggagggagcagcagcagtagtaacagcagtgccggtggaggggct
ggcaagcagaatggcgccaccagttacagctcagttgtggcagacagcccggcagaggtg
gctttgagcagcagtgggggcaacaatgccagcagccaggccttgggccccccttccggc
ccccacaacccacctcccagcacctcgaaggaacccagtgcggcagccccaacgggggct
gggggcgtggccccaggctcagggaacaactcagggggacccagcctcctggtgccactg
cctgtgaatcctcccagctccccaacgcccagcttcagtgatgccaaggcagccggtgcc
ctgctcaatgggcctccacagttcagcaccgccccagaaatcaaggcccctgagcctctg
agctccttgaagtccatggcggaacgggcagccatcagctctggcattgaggaccctgtg
ccaacgctgcacctgaccgagcgagacatcatcctgagcagtacatcagcacctccggcc
tcagcccagccgcccctgcagctgtcagaggtgaacataccgctgtcgctgggtgtctgt
ccactgggccctgtgcccctcaccaaggagcagctctatcagcaggccatggaagaggcc
gcctggcaccacatgcctcacccctctgactctgagcgtattcggcagtacctcccccgg
aacccctgtccgacgcccccctaccaccaccagatgccacccccacactcggacactgtg
gaattctaccagcgcctgtcgaccgagacactcttcttcatcttctactatctggagggc
actaaggcacagtatctggcagccaaggccctaaagaagcagtcatggcgattccacacc
aagtacatgatgtggttccagaggcacgaggagcccaagaccatcactgacgagtttgag
cagggcacctacatctactttgactacgagaagtggggccagcggaagaaggaaggcttc
acctttgagtaccgctacctggaggaccgggacctccagtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (42)   
   KEGG ORTHOLOGY (1)   
   RefGene (33)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
Protein sequence (24)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (21)   
DNA sequence (47)   
   RefSeq(nuc) (21)   
   GenBank (13)   
   EMBL (13)   
3D Structure (4)   
   PDB (4)   
Protein domain (2)   
   Pfam (2)   
All databases (126)   

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