KEGG   Homo sapiens (human): 4849
Entry
4849              CDS       T01001                                 
Symbol
CNOT3, IDDSADF, LENG2, NOT3, NOT3H
Name
(RefSeq) CCR4-NOT transcription complex subunit 3
  KO
K12580  CCR4-NOT transcription complex subunit 3
Organism
hsa  Homo sapiens (human)
Pathway
hsa03018  RNA degradation
Disease
H02700  Intellectual developmental disorder with speech delay and dysmorphic facies
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    4849 (CNOT3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    4849 (CNOT3)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    P-body specific factors
     4849 (CNOT3)
  mRNA degradation factors
   3'-5' decay
    Ccr4-NOT complex
     4849 (CNOT3)
SSDB
Motif
Pfam: Not3 NOT2_3_5_C DUF4407 PI3K_P85_iSH2
Other DBs
NCBI-GeneID: 4849
NCBI-ProteinID: NP_055331
OMIM: 604910
HGNC: 7879
Ensembl: ENSG00000088038
UniProt: O75175
Structure
Position
19:54137762..54155681
AA seq 753 aa
MADKRKLQGEIDRCLKKVSEGVEQFEDIWQKLHNAANANQKEKYEADLKKEIKKLQRLRD
QIKTWVASNEIKDKRQLIDNRKLIETQMERFKVVERETKTKAYSKEGLGLAQKVDPAQKE
KEEVGQWLTNTIDTLNMQVDQFESEVESLSVQTRKKKGDKDKQDRIEGLKRHIEKHRYHV
RMLETILRMLDNDSILVDAIRKIKDDVEYYVDSSQDPDFEENEFLYDDLDLEDIPQALVA
TSPPSHSHMEDEIFNQSSSTPTSTTSSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSP
AKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPA
PSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGA
GKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGA
GGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPL
SSLKSMAERAAISSGIEDPVPTLHLTERDIILSSTSAPPASAQPPLQLSEVNIPLSLGVC
PLGPVPLTKEQLYQQAMEEAAWHHMPHPSDSERIRQYLPRNPCPTPPYHHQMPPPHSDTV
EFYQRLSTETLFFIFYYLEGTKAQYLAAKALKKQSWRFHTKYMMWFQRHEEPKTITDEFE
QGTYIYFDYEKWGQRKKEGFTFEYRYLEDRDLQ
NT seq 2262 nt   +upstreamnt  +downstreamnt
atggcggacaagcgcaaactccaaggtgagattgatcgctgcctcaagaaggtgtccgag
ggcgtggagcagtttgaagatatttggcagaagctccacaatgcagccaacgcgaaccag
aaagaaaagtatgaggctgacctaaagaaggagattaagaagctacaacggctgagggac
caaatcaagacatgggtagcgtccaacgagatcaaggacaagaggcagcttatagacaac
cgcaagctcattgagacgcaaatggaacggttcaaagttgtggaacgagagaccaaaacc
aaagcttacagcaaagagggcctgggcctggcccagaaggtagatcctgcccagaaggag
aaggaagaggttggccagtggctcacgaataccatcgacacgctcaacatgcaggtggac
cagtttgagagtgaagtggagtcactgtcagtgcagacacgcaagaagaagggcgacaag
gataagcaggaccggattgagggcttgaagcggcacatcgagaagcaccgctaccacgtg
cgcatgctagagaccatcctgcgcatgctggacaatgactccatcctcgttgacgccatc
cgcaagatcaaggacgacgttgagtactatgttgactcatcccaggaccccgacttcgag
gagaacgagtttctctacgatgacctggacctcgaggacattccacaggcgctggtcgcc
acctccccccccagccacagccacatggaggatgagatcttcaaccagtccagcagcacg
cccacctcaaccacctccagctctcccatcccgcccagcccagccaactgtaccacggaa
aactctgaagatgataagaagaggggacgttccacagacagtgaagtcagccagtctcca
gccaaaaacggctccaagcctgtccacagcaaccagcaccctcagtccccagctgtgccg
cccacctacccctccggccccccgcctgctgcctctgccttgagcaccactcctggcaac
aatggggtccccgcccccgcagcacccccaagtgccctgggccccaaggccagtccagct
cccagccacaactcgggcacccctgctccctatgcccaggctgtggccccaccagctccc
agtgggcccagcacgacccagccccggccccccagcgtccagcctagcggaggcggaggc
ggcggcagcggaggcggagggagcagcagcagtagtaacagcagtgccggtggaggggct
ggcaagcagaatggcgccaccagttacagctcagttgtggcagacagcccggcagaggtg
gctttgagcagcagtgggggcaacaatgccagcagccaggccttgggccccccttccggc
ccccacaacccacctcccagcacctcgaaggaacccagtgcggcagccccaacgggggct
gggggcgtggccccaggctcagggaacaactcagggggacccagcctcctggtgccactg
cctgtgaatcctcccagctccccaacgcccagcttcagtgatgccaaggcagccggtgcc
ctgctcaatgggcctccacagttcagcaccgccccagaaatcaaggcccctgagcctctg
agctccttgaagtccatggcggaacgggcagccatcagctctggcattgaggaccctgtg
ccaacgctgcacctgaccgagcgagacatcatcctgagcagtacatcagcacctccggcc
tcagcccagccgcccctgcagctgtcagaggtgaacataccgctgtcgctgggtgtctgt
ccactgggccctgtgcccctcaccaaggagcagctctatcagcaggccatggaagaggcc
gcctggcaccacatgcctcacccctctgactctgagcgtattcggcagtacctcccccgg
aacccctgtccgacgcccccctaccaccaccagatgccacccccacactcggacactgtg
gaattctaccagcgcctgtcgaccgagacactcttcttcatcttctactatctggagggc
actaaggcacagtatctggcagccaaggccctaaagaagcagtcatggcgattccacacc
aagtacatgatgtggttccagaggcacgaggagcccaagaccatcactgacgagtttgag
cagggcacctacatctactttgactacgagaagtggggccagcggaagaaggaaggcttc
acctttgagtaccgctacctggaggaccgggacctccagtga

  All links  
Disease (2)   
   OMIM (2)   
Gene (40)   
   RefGene (33)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (226)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (224)   
DNA sequence (252)   
   RefSeq(nuc) (226)   
   GenBank (13)   
   EMBL (13)   
3D Structure (6)   
   PDB (6)   
Protein domain (4)   
   Pfam (4)   
All databases (530)   

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