KEGG   Homo sapiens (human): 4921
Entry
4921              CDS       T01001                                 
Symbol
DDR2, MIG20a, NTRKR3, TKT, TYRO10, WRCN
Name
(RefSeq) discoidin domain receptor tyrosine kinase 2
  KO
K05125  discoidin domain receptor family member 2 [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Disease
H00777  SEMD, short limb-hand type
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    4921 (DDR2)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    4921 (DDR2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     4921 (DDR2)
Protein kinases [BR:hsa01001]
 Receptor tyrosine kinases (RTK)
  DDR family
   4921 (DDR2)
CD molecules [BR:hsa04090]
 Proteins
  4921 (DDR2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr DDR1-2_DS-like Pkinase F5_F8_type_C Haspin_kinase ABC1 DUF7318
Other DBs
NCBI-GeneID: 4921
NCBI-ProteinID: NP_001014796
OMIM: 191311
HGNC: 2731
Ensembl: ENSG00000162733
UniProt: Q16832
Structure
Position
1:162630863..162787405
AA seq 855 aa
MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY
GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI
NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV
ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD
DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS
EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL
WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD
YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV
PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN
QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG
DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK
NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET
FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP
SFQEIHLLLLQQGDE
NT seq 2568 nt   +upstreamnt  +downstreamnt
atgatcctgattcccagaatgctcttggtgctgttcctgctgctgcctatcttgagttct
gcaaaagctcaggttaatccagctatatgccgctatcctctgggcatgtcaggaggccag
attccagatgaggacatcacagcttccagtcagtggtcagagtccacagctgccaaatat
ggaaggctggactcagaagaaggggatggagcctggtgccctgagattccagtggaacct
gatgacctgaaggagtttctgcagattgacttgcacaccctccattttatcactctggtg
gggacccaggggcgccatgcaggaggtcatggcatcgagtttgcccccatgtacaagatc
aattacagtcgggatggcactcgctggatctcttggcggaaccgtcatgggaaacaggtg
ctggatggaaatagtaacccctatgacattttcctaaaggacttggagccgcccattgta
gccagatttgtccggttcattccagtcaccgaccactccatgaatgtgtgtatgagagtg
gagctttacggctgtgtctggctagatggcttggtgtcttacaatgctccagctgggcag
cagtttgtactccctggaggttccatcatttatctgaatgattctgtctatgatggagct
gttggatacagcatgacagaagggctaggccaattgaccgatggtgtgtctggcctggac
gatttcacccagacccatgaataccacgtgtggcccggctatgactatgtgggctggcgg
aacgagagtgccaccaatggctacattgagatcatgtttgaatttgaccgcatcaggaat
ttcactaccatgaaggtccactgcaacaacatgtttgctaaaggtgtgaagatctttaag
gaggtacagtgctacttccgctctgaagccagtgagtgggaacctaatgccatttccttc
ccccttgtcctggatgacgtcaaccccagtgctcggtttgtcacggtgcctctccaccac
cgaatggccagtgccatcaagtgtcaataccattttgcagatacctggatgatgttcagt
gagatcaccttccaatcagatgctgcaatgtacaacaactctgaagccctgcccacctct
cctatggcacccacaacctatgatccaatgcttaaagttgatgacagcaacactcggatc
ctgattggctgcttggtggccatcatctttatcctcctggccatcattgtcatcatcctc
tggaggcagttctggcagaaaatgctggagaaggcttctcggaggatgctggatgatgaa
atgacagtcagcctttccctgccaagtgattctagcatgttcaacaataaccgctcctca
tcacctagtgaacaagggtccaactcgacttacgatcgcatctttccccttcgccctgac
taccaggagccatccaggctgatacgaaaactcccagaatttgctccaggggaggaggag
tcaggctgcagcggtgttgtgaagccagtccagcccagtggccctgagggggtgccccac
tatgcagaggctgacatagtgaacctccaaggagtgacaggaggcaacacatactcagtg
cctgccgtcaccatggacctgctctcaggaaaagatgtggctgtggaggagttccccagg
aaactcctaactttcaaagagaagctgggagaaggacagtttggggaggttcatctctgt
gaagtggagggaatggaaaaattcaaagacaaagattttgccctagatgtcagtgccaac
cagcctgtcctggtggctgtgaaaatgctccgagcagatgccaacaagaatgccaggaat
gattttcttaaggagataaagatcatgtctcggctcaaggacccaaacatcatccatcta
ttagctgtgtgtatcactgatgaccctctctgtatgatcactgaatacatggagaatgga
gatctcaatcagtttctttcccgccacgagccccctaattcttcctccagcgatgtacgc
actgtcagttacaccaatctgaagtttatggctacccaaattgcctctggcatgaagtac
ctttcctctcttaattttgttcaccgagatctggccacacgaaactgtttagtgggtaag
aactacacaatcaagatagctgactttggaatgagcaggaacctgtacagtggtgactat
taccggatccagggccgggcagtgctccctatccgctggatgtcttgggagagtatcttg
ctgggcaagttcactacagcaagtgatgtgtgggcctttggggttactttgtgggagact
ttcaccttttgtcaagaacagccctattcccagctgtcagatgaacaggttattgagaat
actggagagttcttccgagaccaagggaggcagacttacctccctcaaccagccatttgt
cctgactctgtgtataagctgatgctcagctgctggagaagagatacgaagaaccgtccc
tcattccaagaaatccaccttctgctccttcaacaaggcgacgagtga

  All links  
Disease (3)   
   OMIM (3)   
Gene (13)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (52)   
   RefSeq(nuc) (12)   
   GenBank (20)   
   EMBL (20)   
3D Structure (5)   
   PDB (5)   
Protein domain (7)   
   Pfam (7)   
All databases (94)   

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