KEGG   Homo sapiens (human): 4921Help
Entry
4921              CDS       T01001                                 

Gene name
DDR2, MIG20a, NTRKR3, TKT, TYRO10
Definition
(RefSeq) discoidin domain receptor tyrosine kinase 2
  KO
K05125  discoidin domain receptor family member 2 [EC:2.7.10.1]
Organism
hsa  Homo sapiens (human)
Disease
H00777  SEMD, short limb-hand type
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    4921 (DDR2)
  09183 Protein families: signaling and cellular processes
   04090 CD molecules [BR:hsa04090]
    4921 (DDR2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     4921 (DDR2)
Protein kinases [BR:hsa01001]
 Receptor tyrosine kinases (RTK)
  DDR family
   4921 (DDR2)
CD molecules [BR:hsa04090]
 Proteins
  4921 (DDR2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase_Tyr Pkinase F5_F8_type_C Haspin_kinase
Motif
Other DBs
NCBI-GeneID: 4921
NCBI-ProteinID: NP_001014796
OMIM: 191311
HGNC: 2731
Ensembl: ENSG00000162733
Vega: OTTHUMG00000034423
Pharos: Q16832(Tchem)
UniProt: Q16832 A0A024R906
Structure
PDB: 

Position
1q23.3
AA seq 855 aa AA seqDB search
MILIPRMLLVLFLLLPILSSAKAQVNPAICRYPLGMSGGQIPDEDITASSQWSESTAAKY
GRLDSEEGDGAWCPEIPVEPDDLKEFLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKI
NYSRDGTRWISWRNRHGKQVLDGNSNPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRV
ELYGCVWLDGLVSYNAPAGQQFVLPGGSIIYLNDSVYDGAVGYSMTEGLGQLTDGVSGLD
DFTQTHEYHVWPGYDYVGWRNESATNGYIEIMFEFDRIRNFTTMKVHCNNMFAKGVKIFK
EVQCYFRSEASEWEPNAISFPLVLDDVNPSARFVTVPLHHRMASAIKCQYHFADTWMMFS
EITFQSDAAMYNNSEALPTSPMAPTTYDPMLKVDDSNTRILIGCLVAIIFILLAIIVIIL
WRQFWQKMLEKASRRMLDDEMTVSLSLPSDSSMFNNNRSSSPSEQGSNSTYDRIFPLRPD
YQEPSRLIRKLPEFAPGEEESGCSGVVKPVQPSGPEGVPHYAEADIVNLQGVTGGNTYSV
PAVTMDLLSGKDVAVEEFPRKLLTFKEKLGEGQFGEVHLCEVEGMEKFKDKDFALDVSAN
QPVLVAVKMLRADANKNARNDFLKEIKIMSRLKDPNIIHLLAVCITDDPLCMITEYMENG
DLNQFLSRHEPPNSSSSDVRTVSYTNLKFMATQIASGMKYLSSLNFVHRDLATRNCLVGK
NYTIKIADFGMSRNLYSGDYYRIQGRAVLPIRWMSWESILLGKFTTASDVWAFGVTLWET
FTFCQEQPYSQLSDEQVIENTGEFFRDQGRQTYLPQPAICPDSVYKLMLSCWRRDTKNRP
SFQEIHLLLLQQGDE
NT seq 2568 nt NT seq  +upstreamnt  +downstreamnt
atgatcctgattcccagaatgctcttggtgctgttcctgctgctgcctatcttgagttct
gcaaaagctcaggttaatccagctatatgccgctatcctctgggcatgtcaggaggccag
attccagatgaggacatcacagcttccagtcagtggtcagagtccacagctgccaaatat
ggaaggctggactcagaagaaggggatggagcctggtgccctgagattccagtggaacct
gatgacctgaaggagtttctgcagattgacttgcacaccctccattttatcactctggtg
gggacccaggggcgccatgcaggaggtcatggcatcgagtttgcccccatgtacaagatc
aattacagtcgggatggcactcgctggatctcttggcggaaccgtcatgggaaacaggtg
ctggatggaaatagtaacccctatgacattttcctaaaggacttggagccgcccattgta
gccagatttgtccggttcattccagtcaccgaccactccatgaatgtgtgtatgagagtg
gagctttacggctgtgtctggctagatggcttggtgtcttacaatgctccagctgggcag
cagtttgtactccctggaggttccatcatttatctgaatgattctgtctatgatggagct
gttggatacagcatgacagaagggctaggccaattgaccgatggtgtgtctggcctggac
gatttcacccagacccatgaataccacgtgtggcccggctatgactatgtgggctggcgg
aacgagagtgccaccaatggctacattgagatcatgtttgaatttgaccgcatcaggaat
ttcactaccatgaaggtccactgcaacaacatgtttgctaaaggtgtgaagatctttaag
gaggtacagtgctacttccgctctgaagccagtgagtgggaacctaatgccatttccttc
ccccttgtcctggatgacgtcaaccccagtgctcggtttgtcacggtgcctctccaccac
cgaatggccagtgccatcaagtgtcaataccattttgcagatacctggatgatgttcagt
gagatcaccttccaatcagatgctgcaatgtacaacaactctgaagccctgcccacctct
cctatggcacccacaacctatgatccaatgcttaaagttgatgacagcaacactcggatc
ctgattggctgcttggtggccatcatctttatcctcctggccatcattgtcatcatcctc
tggaggcagttctggcagaaaatgctggagaaggcttctcggaggatgctggatgatgaa
atgacagtcagcctttccctgccaagtgattctagcatgttcaacaataaccgctcctca
tcacctagtgaacaagggtccaactcgacttacgatcgcatctttccccttcgccctgac
taccaggagccatccaggctgatacgaaaactcccagaatttgctccaggggaggaggag
tcaggctgcagcggtgttgtgaagccagtccagcccagtggccctgagggggtgccccac
tatgcagaggctgacatagtgaacctccaaggagtgacaggaggcaacacatactcagtg
cctgccgtcaccatggacctgctctcaggaaaagatgtggctgtggaggagttccccagg
aaactcctaactttcaaagagaagctgggagaaggacagtttggggaggttcatctctgt
gaagtggagggaatggaaaaattcaaagacaaagattttgccctagatgtcagtgccaac
cagcctgtcctggtggctgtgaaaatgctccgagcagatgccaacaagaatgccaggaat
gattttcttaaggagataaagatcatgtctcggctcaaggacccaaacatcatccatcta
ttagctgtgtgtatcactgatgaccctctctgtatgatcactgaatacatggagaatgga
gatctcaatcagtttctttcccgccacgagccccctaattcttcctccagcgatgtacgc
actgtcagttacaccaatctgaagtttatggctacccaaattgcctctggcatgaagtac
ctttcctctcttaattttgttcaccgagatctggccacacgaaactgtttagtgggtaag
aactacacaatcaagatagctgactttggaatgagcaggaacctgtacagtggtgactat
taccggatccagggccgggcagtgctccctatccgctggatgtcttgggagagtatcttg
ctgggcaagttcactacagcaagtgatgtgtgggcctttggggttactttgtgggagact
ttcaccttttgtcaagaacagccctattcccagctgtcagatgaacaggttattgagaat
actggagagttcttccgagaccaagggaggcagacttacctccctcaaccagccatttgt
cctgactctgtgtataagctgatgctcagctgctggagaagagatacgaagaaccgtccc
tcattccaagaaatccaccttctgctccttcaacaaggcgacgagtga

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Ontology (6)   
   KEGG BRITE (6)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (6)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (2)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (2)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (9)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (6)   
DNA sequence (44)   
   RefSeq(nuc) (6)   
   GenBank (19)   
   EMBL (19)   
Protein domain (4)   
   Pfam (4)   
All databases (86)   

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