KEGG   Homo sapiens (human): 4926
Entry
4926              CDS       T01001                                 
Symbol
NUMA1, NMP-22, NUMA
Name
(RefSeq) nuclear mitotic apparatus protein 1
  KO
K16808  nuclear mitotic apparatus protein 1
Organism
hsa  Homo sapiens (human)
Disease
H02542  Acute promyelocytic leukemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    4926 (NUMA1)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Centrosome formation proteins
   Spindle formation proteins
    4926 (NUMA1)
SSDB
Motif
Pfam: HOOK_N_NuMA Leu_zip
Other DBs
NCBI-GeneID: 4926
NCBI-ProteinID: NP_006176
OMIM: 164009
HGNC: 8059
Ensembl: ENSG00000137497
UniProt: Q14980 Q3SYK8 Q4LE64
Structure
Position
11:complement(72002864..72080542)
AA seq 2115 aa
MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSER
LDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFE
YKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIR
FLELQKVASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAEN
RKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQ
DLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQA
QLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQ
EAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQ
AKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQ
QQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEEREASLRERD
AALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVE
TARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE
EKRRAADALEEQQRCISELKAETRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQA
ETEVLRRELAEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKE
ECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLAD
DLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQF
CSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADL
ALEKAARAELEMRLQNALNEQRVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKEL
EELRQTVKQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQ
EQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ
DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESE
KSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAE
RAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKR
HREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSML
KKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQS
TARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLAD
SDQASKVQQQKLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTH
YDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQV
RSLEAQVAHADQQLRDLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSK
LPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDS
GRKTRSARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAPASQASLRATSSTQSLARL
GSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSFYMGTCQDEPEQLDDWNRI
AELQQRNRVCPPHLKTCYPLESRPSLSLGTITDEEMKTGDPQETLRRASMQPIQIAEGTG
ITTRQQRKRVSLEPHQGPGTPESKKATSCFPRPMTPRDRHEGRKQSTTEAQKKAAPASTK
QADRRQSMAFSILNTPKKLGNSLLRRGASKKALSKASPNTRSGTRRSPRIATTTASAATA
AAIGATPRAKGKAKH
NT seq 6348 nt   +upstreamnt  +downstreamnt
atgacactccacgccacccggggggctgcactcctctcttgggtgaacagtctacacgtg
gctgaccctgtggaggctgtgctgcagctccaggactgcagcatcttcatcaagatcatt
gacagaatccatggcactgaagagggacagcaaatcttgaagcagccggtgtcagagaga
ctggactttgtgtgcagttttctgcagaaaaatcgaaaacatccctcttccccagaatgc
ctggtatctgcacagaaggtgctagagggatcagagctggaactggcgaagatgaccatg
ctgctcttataccactctaccatgagctccaaaagtcccagggactgggaacagtttgaa
tataaaattcaggctgagttggctgtcattcttaaatttgtgctggaccatgaggacggg
ctaaaccttaatgaggacctagagaacttcctacagaaagctcctgtgccttctacctgt
tctagcacattccctgaagagctctccccacctagccaccaggccaagagggagattcgc
ttcctagagctacagaaggttgcctcctcttccagtgggaacaactttctctcaggttct
ccagcttctcccatgggtgatatcctgcagaccccacagttccagatgagacggctgaag
aagcagcttgctgatgagagaagtaatagggatgagctggagctggagctagctgagaac
cgcaagctcctcaccgagaaggatgcacagatagccatgatgcagcagcgcattgaccgc
ctagccctgctgaatgagaagcaggcggccagcccactggagcccaaggagcttgaggag
ctgcgtgacaagaatgagagccttaccatgcggctgcatgaaaccctgaagcagtgccag
gacctgaagacagagaagagccagatggatcgcaaaatcaaccagctttcggaggagaat
ggagacctttcctttaagctgcgggagtttgccagtcatctgcagcagctacaggatgcc
ctcaatgagctgacggaggagcacagcaaggccactcaggagtggctagagaagcaggcc
cagctggagaaggagctcagcgcagccctgcaggacaagaaatgccttgaagagaagaac
gaaatccttcagggaaaactttcacagctggaagaacacttgtcccagctgcaggataac
ccaccccaggagaagggcgaggtgctgggtgatgtcttgcagctggaaaccttgaagcaa
gaggcagccactcttgctgcaaacaacacacagctccaagccagggtagagatgctggag
actgagcgaggccagcaggaagccaagctgcttgctgagcggggccacttcgaagaagaa
aagcagcagctgtctagcctgatcactgacctgcagagctccatctccaacctcagccag
gccaaggaagagctggagcaggcctcccaggctcatggggcccggttgactgcccaggtg
gcctctctgacctctgagctcaccacactcaatgccaccatccagcaacaggatcaagaa
ctggctggcctgaagcagcaggccaaagagaagcaggcccagctagcacagaccctccaa
cagcaagaacaggcctcccagggcctccgccaccaggtggagcagctaagcagtagcctg
aagcagaaggagcagcagttgaaggaggtagcggagaagcaggaggcaactaggcaggac
catgcccagcaactggccactgctgcagaggagcgagaggcctccttaagggagcgggat
gcggctctcaagcagctggaggcactggagaaggagaaggctgccaagctggagattctg
cagcagcaacttcaggtggctaatgaagcccgggacagtgcccagacctcagtgacacag
gcccagcgggagaaggcagagctgagccggaaggtggaggaactccaggcctgtgttgag
acagcccgccaggaacagcatgaggcccaggcccaggttgcagagctagagttgcagctg
cggtctgagcagcaaaaagcaactgagaaagaaagggtggcccaggagaaggaccagctc
caggagcagctccaggccctcaaagagtccttgaaggtcaccaagggcagccttgaagag
gagaagcgcagggctgcagatgccctggaagagcagcagcgttgtatctctgagctgaag
gcagagacccgaagcctggtggagcagcataagcgggaacgaaaggagctggaagaagag
agggctgggcgcaaggggctggaggctcgattacagcagcttggggaggcccatcaggct
gagactgaagtcctgcggcgggagctggcagaggccatggctgcccagcacacagctgag
agtgagtgtgagcagctcgtcaaagaagtagctgcctggcgtgagcggtatgaggatagc
cagcaagaggaggcacagtatggcgccatgttccaggaacagctgatgactttgaaggag
gaatgtgagaaggcccgccaggagctgcaggaggcaaaggagaaggtggcaggcatagaa
tcccacagcgagctccagataagccggcagcagaacgaactagctgagctccatgccaac
ctggccagagcactccagcaggtccaagagaaggaagtcagggcccagaagcttgcagat
gacctctccactctgcaggaaaagatggctgccaccagcaaagaggtggcccgcttggag
accttggtgcgcaaggcaggtgagcagcaggaaacagcctcccgggagttagtcaaggag
cctgcgagggcaggagacagacagcccgagtggctggaagagcaacagggacgccagttc
tgcagcacacaggcagcgctgcaggctatggagcgggaggcagagcagatgggcaatgag
ctggaacggctgcgggccgcgctgatggagagccaggggcagcagcaggaggagcgtggg
cagcaggaaagggaggtggcgcggctgacccaggagcggggccgtgcccaggctgacctt
gccctggagaaggcggccagagcagagcttgagatgcggctgcagaacgccctcaacgag
cagcgtgtggagttcgctaccctgcaagaggcactggctcatgccctgacggaaaaggaa
ggcaaggaccaggagttggccaagcttcgtggtctggaggcagcccagataaaagagctg
gaggaacttcggcaaaccgtgaagcaactgaaggaacagctggctaagaaagaaaaggag
cacgcatctggctcaggagcccaatctgaggctgctggcaggacagagccaacaggcccc
aagctggaggcactgcgggcagaggtgagcaagctggaacagcaatgccagaagcagcag
gagcaggctgacagcctggaacgcagcctcgaggctgagcgggcctcccgggctgagcgg
gacagtgctctggagactctgcagggccagttagaggagaaggcccaggagctagggcac
agtcagagtgccttagcctcggcccaacgggagttggctgccttccgcaccaaggtacaa
gaccacagcaaggctgaagatgagtggaaggcccaggtggcccggggccggcaagaggct
gagaggaaaaatagcctcatcagcagcttggaggaggaggtgtccatcctgaatcgccag
gtcctggagaaggagggggagagcaaggagttgaagcggctggtgatggccgagtcagag
aagagccagaagctggaggagaggctgcgcctgctgcaggcagagacagccagcaacagt
gccagagctgcagaacgcagctctgctctgcgggaggaggtgcagagcctccgggaggag
gctgagaaacagcgggtggcttcagagaacctgcggcaggagctgacctcacaggctgag
cgtgcggaggagctgggccaagaattgaaggcgtggcaggagaagttcttccagaaagag
caggccctctccaccctgcagctcgagcacaccagcacacaggccctggtgagtgagctg
ctgccagctaagcacctctgccagcagctgcaggccgagcaggccgctgccgagaaacgc
caccgtgaggagctggagcagagcaagcaggccgctgggggactgcgggcagagctgctg
cgggcccagcgggagcttggggagctgattcctctgcggcagaaggtggcagagcaggag
cgaacagctcagcagctgcgggcagagaaggccagctatgcagagcagctgagcatgctg
aagaaggcgcatggcctgctggcagaggagaaccgggggctgggtgagcgggccaacctt
ggccggcagtttctggaagtggagttggaccaggcccgggagaagtatgtccaagagttg
gcagccgtacgtgctgatgctgagacccgtctggctgaggtgcagcgagaagcacagagc
actgcccgggagctggaggtgatgactgccaagtatgagggtgccaaggtcaaggtcctg
gaggagaggcagcggttccaggaagagaggcagaaactcactgcccaggtggagcagcta
gaggtatttcagagagagcaaactaagcaggtggaagaactgagtaagaaactggctgac
tctgaccaagccagcaaggtgcagcagcagaagctgaaggctgtccaggctcagggaggc
gagagccagcaggaggcccagcgcctccaggcccagctgaatgaactgcaagcccagttg
agccagaaggagcaggcagctgagcactataagctgcagatggagaaagccaaaacacat
tatgatgccaagaagcagcagaaccaagagctgcaggagcagctgcggagcctggagcag
ctgcagaaggaaaacaaagagctgcgagctgaagctgaacggctgggccatgagctacag
caggctgggctgaagaccaaggaggctgaacagacctgccgccaccttactgcccaggtg
cgcagcctggaggcacaggttgcccatgcagaccagcagcttcgagacctgggcaaattc
caggtggcaactgatgctttaaagagccgtgagccccaggctaagccccagctggacttg
agtattgacagcctggatctgagctgcgaggaggggaccccactcagtatcaccagcaag
ctgcctcgtacccagccagacggcaccagcgtccctggagaaccagcctcacctatctcc
cagcgcctgccccccaaggtagaatccctggagagtctctacttcactcccatccctgct
cggagtcaggcccccctggagagcagcctggactccctgggagacgtcttcctggactcg
ggtcgtaagacccgctccgctcgtcggcgcaccacgcagatcatcaacatcaccatgacc
aagaagctagatgtggaagagccagacagcgccaactcatcgttctacagcacgcggtct
gctcctgcttcccaggctagcctgcgagccacctcctctactcagtctctagctcgcctg
ggttctcccgattatggcaactcagccctgctcagcttgcctggctaccgccccaccact
cgcagttctgctcgtcgttcccaggccggggtgtccagtggggcccctccaggaaggaac
agcttctacatgggcacttgccaggatgagcctgagcagctggatgactggaaccgcatt
gcagagctgcagcagcgcaatcgagtgtgccccccacatctgaagacctgctatcccctg
gagtccaggccttccctgagcctgggcaccatcacagatgaggagatgaaaactggagac
ccccaagagaccctgcgccgagccagcatgcagccaatccagatagccgagggcactggc
atcaccacccggcagcagcgcaaacgggtctccctagagccccaccagggccctggaact
cctgagtctaagaaggccaccagctgtttcccacgccccatgactccccgagaccgacat
gaagggcgcaaacagagcactactgaggcccagaagaaagcagctccagcttctactaaa
caggctgaccggcgccagtcgatggccttcagcatcctcaacacacccaagaagctaggg
aacagccttctgcggcggggagcctcaaagaaggccctgtccaaggcttcccccaacact
cgcagtggaacccgccgttctccgcgcattgccaccaccacagccagcgccgccactgct
gccgccattggtgccacccctcgagccaagggcaaggcaaagcactaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (93)   
   RefGene (85)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (104)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (100)   
DNA sequence (147)   
   RefSeq(nuc) (101)   
   GenBank (23)   
   EMBL (23)   
3D Structure (4)   
   PDB (4)   
Protein domain (2)   
   Pfam (2)   
All databases (351)   

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