KEGG   Homo sapiens (human): 4987
Entry
4987              CDS       T01001                                 
Symbol
OPRL1, KOR-3, KOR3, NOCIR, NOP, NOPr, OOR, OPRL, ORL1, PNOCR
Name
(RefSeq) opioid related nociceptin receptor 1
  KO
K04216  nociceptin receptor
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04081  Hormone signaling
hsa04082  Neuroactive ligand signaling
Drug target
Cebranopadol: D10436
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    4987 (OPRL1)
   04082 Neuroactive ligand signaling
    4987 (OPRL1)
   04081 Hormone signaling
    4987 (OPRL1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    4987 (OPRL1)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Opioid
    4987 (OPRL1)
SSDB
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srv 7tm_4 7TM_GPCR_Srx PqiA V1R
Other DBs
NCBI-GeneID: 4987
NCBI-ProteinID: NP_000904
OMIM: 602548
HGNC: 8155
Ensembl: ENSG00000125510
UniProt: P41146
Structure
Position
20:64080082..64100643
AA seq 370 aa
MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
KTSETVPRPA
NT seq 1113 nt   +upstreamnt  +downstreamnt
atggagcccctcttccccgcgccgttctgggaggttatctacggcagccaccttcagggc
aacctgtccctcctgagccccaaccacagtctgctgcccccgcatctgctgctcaatgcc
agccacggcgccttcctgcccctcgggctcaaggtcaccatcgtggggctctacctggcc
gtgtgtgtcggagggctcctggggaactgccttgtcatgtacgtcatcctcaggcacacc
aaaatgaagacagccaccaatatttacatctttaacctggccctggccgacactctggtc
ctgctgacgctgcccttccagggcacggacatcctcctgggcttctggccgtttgggaat
gcgctgtgcaagacagtcattgccattgactactacaacatgttcaccagcaccttcacc
ctaactgccatgagtgtggatcgctatgtagccatctgccaccccatccgtgccctcgac
gtccgcacgtccagcaaagcccaggctgtcaatgtggccatctgggccctggcctctgtt
gtcggtgttcccgttgccatcatgggctcggcacaggtcgaggatgaagagatcgagtgc
ctggtggagatccctacccctcaggattactggggcccggtgtttgccatctgcatcttc
ctcttctccttcatcgtccccgtgctcgtcatctctgtctgctacagcctcatgatccgg
cggctccgtggagtccgcctgctctcgggctcccgagagaaggaccggaacctgcggcgc
atcactcggctggtgctggtggtagtggctgtgttcgtgggctgctggacgcctgtccag
gtcttcgtgctggcccaagggctgggggttcagccgagcagcgagactgccgtggccatt
ctgcgcttctgcacggccctgggctacgtcaacagctgcctcaaccccatcctctacgcc
ttcctggatgagaacttcaaggcctgcttccgcaagttctgctgtgcatctgccctgcgc
cgggacgtgcaggtgtctgaccgcgtgcgcagcattgccaaggacgtggccctggcctgc
aagacctctgagacggtaccgcggcccgcatga

  All links  
Disease (1)   
   OMIM (1)   
Gene (8)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (23)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (21)   
DNA sequence (91)   
   RefSeq(nuc) (21)   
   GenBank (35)   
   EMBL (35)   
3D Structure (4)   
   PDB (4)   
Protein domain (7)   
   Pfam (7)   
All databases (134)   

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