KEGG   Homo sapiens (human): 4987
Entry
4987              CDS       T01001                                 
Symbol
OPRL1, KOR-3, KOR3, NOCIR, NOP, NOPr, OOR, OPRL, ORL1, PNOCR
Name
(RefSeq) opioid related nociceptin receptor 1
  KO
K04216  nociceptin receptor
Organism
hsa  Homo sapiens (human)
Pathway
hsa04080  Neuroactive ligand-receptor interaction
Drug target
Cebranopadol: D10436
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    4987 (OPRL1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:hsa04030]
    4987 (OPRL1)
G protein-coupled receptors [BR:hsa04030]
 Rhodopsin family
  Peptide
   Opioid
    4987 (OPRL1)
SSDB
Motif
Pfam: 7tm_1 7TM_GPCR_Srsx 7TM_GPCR_Srv 7tm_4 7TM_GPCR_Srx PqiA V1R
Other DBs
NCBI-GeneID: 4987
NCBI-ProteinID: NP_000904
OMIM: 602548
HGNC: 8155
Ensembl: ENSG00000125510
Pharos: P41146(Tchem)
UniProt: P41146
Structure
Position
20:64080082..64100643
AA seq 370 aa
MEPLFPAPFWEVIYGSHLQGNLSLLSPNHSLLPPHLLLNASHGAFLPLGLKVTIVGLYLA
VCVGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGN
ALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASV
VGVPVAIMGSAQVEDEEIECLVEIPTPQDYWGPVFAICIFLFSFIVPVLVISVCYSLMIR
RLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLAQGLGVQPSSETAVAI
LRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALRRDVQVSDRVRSIAKDVALAC
KTSETVPRPA
NT seq 1113 nt   +upstreamnt  +downstreamnt
atggagcccctcttccccgcgccgttctgggaggttatctacggcagccaccttcagggc
aacctgtccctcctgagccccaaccacagtctgctgcccccgcatctgctgctcaatgcc
agccacggcgccttcctgcccctcgggctcaaggtcaccatcgtggggctctacctggcc
gtgtgtgtcggagggctcctggggaactgccttgtcatgtacgtcatcctcaggcacacc
aaaatgaagacagccaccaatatttacatctttaacctggccctggccgacactctggtc
ctgctgacgctgcccttccagggcacggacatcctcctgggcttctggccgtttgggaat
gcgctgtgcaagacagtcattgccattgactactacaacatgttcaccagcaccttcacc
ctaactgccatgagtgtggatcgctatgtagccatctgccaccccatccgtgccctcgac
gtccgcacgtccagcaaagcccaggctgtcaatgtggccatctgggccctggcctctgtt
gtcggtgttcccgttgccatcatgggctcggcacaggtcgaggatgaagagatcgagtgc
ctggtggagatccctacccctcaggattactggggcccggtgtttgccatctgcatcttc
ctcttctccttcatcgtccccgtgctcgtcatctctgtctgctacagcctcatgatccgg
cggctccgtggagtccgcctgctctcgggctcccgagagaaggaccggaacctgcggcgc
atcactcggctggtgctggtggtagtggctgtgttcgtgggctgctggacgcctgtccag
gtcttcgtgctggcccaagggctgggggttcagccgagcagcgagactgccgtggccatt
ctgcgcttctgcacggccctgggctacgtcaacagctgcctcaaccccatcctctacgcc
ttcctggatgagaacttcaaggcctgcttccgcaagttctgctgtgcatctgccctgcgc
cgggacgtgcaggtgtctgaccgcgtgcgcagcattgccaaggacgtggccctggcctgc
aagacctctgagacggtaccgcggcccgcatga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (10)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
Protein sequence (15)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (13)   
DNA sequence (83)   
   RefSeq(nuc) (13)   
   GenBank (35)   
   EMBL (35)   
3D Structure (3)   
   PDB (3)   
Protein domain (7)   
   Pfam (7)   
All databases (124)   

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