KEGG   Homo sapiens (human): 5023
Entry
5023              CDS       T01001                                 
Symbol
P2RX1, P2X1
Name
(RefSeq) purinergic receptor P2X 1
  KO
K05215  P2X purinoceptor 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04082  Neuroactive ligand signaling
hsa04611  Platelet activation
Network
nt06528  Calcium signaling
nt06544  Neuroactive ligand signaling
  Element
N01642  Ca2+ entry, Ligand-gated Ca2+ channel
N01909  Transport of calcium, P2RX
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    5023 (P2RX1)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    5023 (P2RX1)
   04082 Neuroactive ligand signaling
    5023 (P2RX1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    5023 (P2RX1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    5023 (P2RX1)
Ion channels [BR:hsa04040]
 Ligand-gated channels
  ATP-gated cation channel (P2X)
   5023 (P2RX1)
SSDB
Motif
Pfam: P2X_receptor MASE11
Other DBs
NCBI-GeneID: 5023
NCBI-ProteinID: NP_002549
OMIM: 600845
HGNC: 8533
Ensembl: ENSG00000108405
UniProt: P51575
Structure
Position
17:complement(3896592..3916465)
AA seq 399 aa
MARRFQEELAAFLFEYDTPRMVLVRNKKVGVIFRLIQLVVLVYVIGWVFLYEKGYQTSSG
LISSVSVKLKGLAVTQLPGLGPQVWDVADYVFPAQGDNSFVVMTNFIVTPKQTQGYCAEH
PEGGICKEDSGCTPGKAKRKAQGIRTGKCVAFNDTVKTCEIFGWCPVEVDDDIPRPALLR
EAENFTLFIKNSISFPRFKVNRRNLVEEVNAAHMKTCLFHKTLHPLCPVFQLGYVVQESG
QNFSTLAEKGGVVGITIDWHCDLDWHVRHCRPIYEFHGLYEEKNLSPGFNFRFARHFVEN
GTNYRHLFKVFGIRFDILVDGKAGKFDIIPTMTTIGSGIGIFGVATVLCDLLLLHILPKR
HYYKQKKFKYAEDMGPGAAERDLAATSSTLGLQENMRTS
NT seq 1200 nt   +upstreamnt  +downstreamnt
atggcacggcggttccaggaggagctggccgccttcctcttcgagtatgacaccccccgc
atggtgctggtgcgtaataagaaggtgggcgttatcttccgactgatccagctggtggtc
ctggtctacgtcatcgggtgggtgtttctctatgagaagggctaccagacctcgagcggc
ctcatcagcagtgtctctgtgaaactcaagggcctggccgtgacccagctccctggcctc
ggcccccaggtctgggatgtggctgactacgtcttcccagcccagggggacaactccttc
gtggtcatgaccaatttcatcgtgaccccgaagcagactcaaggctactgcgcagagcac
ccagaagggggcatatgcaaggaagacagtggctgtacccctgggaaggccaagaggaag
gcccaaggcatccgcacgggcaagtgtgtggccttcaacgacactgtgaagacgtgtgag
atctttggctggtgccccgtggaggtggatgacgacatcccgcgccctgcccttctccga
gaggccgagaacttcactcttttcatcaagaacagcatcagctttccacgcttcaaggtc
aacaggcgcaacctggtggaggaggtgaatgctgcccacatgaagacctgcctctttcac
aagaccctgcaccccctgtgcccagtcttccagcttggctacgtggtgcaagagtcaggc
cagaacttcagcaccctggctgagaagggtggagtggttggcatcaccatcgactggcac
tgtgacctggactggcacgtacggcactgcagacccatctatgagttccatgggctgtac
gaagagaaaaatctctccccaggcttcaacttcaggtttgccaggcactttgtggagaac
gggaccaactaccgtcacctcttcaaggtgtttgggattcgctttgacatcctggtggac
ggcaaggccgggaagtttgacatcatccctacaatgaccaccatcggctctggaattggc
atctttggggtggccacagttctctgtgacctgctgctgcttcacatcctgcctaagagg
cactactacaagcagaagaagttcaaatacgctgaggacatggggccaggggcggctgag
cgtgacctcgcagctaccagctccaccctgggcctgcaggagaacatgaggacatcctga

  All links  
Disease (1)   
   OMIM (1)   
Gene (9)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (21)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (19)   
DNA sequence (37)   
   RefSeq(nuc) (19)   
   GenBank (9)   
   EMBL (9)   
3D Structure (5)   
   PDB (5)   
Protein domain (2)   
   Pfam (2)   
All databases (75)   

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