KEGG   Homo sapiens (human): 5025
Entry
5025              CDS       T01001                                 
Symbol
P2RX4, P2X4, P2X4R
Name
(RefSeq) purinergic receptor P2X 4
  KO
K05218  P2X purinoceptor 4
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04082  Neuroactive ligand signaling
Network
nt06528  Calcium signaling
nt06544  Neuroactive ligand signaling
  Element
N01642  Ca2+ entry, Ligand-gated Ca2+ channel
N01909  Transport of calcium, P2RX
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    5025 (P2RX4)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    5025 (P2RX4)
   04082 Neuroactive ligand signaling
    5025 (P2RX4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    5025 (P2RX4)
Ion channels [BR:hsa04040]
 Ligand-gated channels
  ATP-gated cation channel (P2X)
   5025 (P2RX4)
SSDB
Motif
Pfam: P2X_receptor DUF3624
Other DBs
NCBI-GeneID: 5025
NCBI-ProteinID: NP_002551
OMIM: 600846
HGNC: 8535
Ensembl: ENSG00000135124
UniProt: Q99571
Structure
Position
12:121210129..121234106
AA seq 388 aa
MAGCCAALAAFLFEYDTPRIVLIRSRKVGLMNRAVQLLILAYVIGWVFVWEKGYQETDSV
VSSVTTKVKGVAVTNTSKLGFRIWDVADYVIPAQEENSLFVMTNVILTMNQTQGLCPEIP
DATTVCKSDASCTAGSAGTHSNGVSTGRCVAFNGSVKTCEVAAWCPVEDDTHVPQPAFLK
AAENFTLLVKNNIWYPKFNFSKRNILPNITTTYLKSCIYDAKTDPFCPIFRLGKIVENAG
HSFQDMAVEGGIMGIQVNWDCNLDRAASLCLPRYSFRRLDTRDVEHNVSPGYNFRFAKYY
RDLAGNEQRTLIKAYGIRFDIIVFGKAGKFDIIPTMINIGSGLALLGMATVLCDIIVLYC
MKKRLYYREKKYKYVEDYEQGLASELDQ
NT seq 1167 nt   +upstreamnt  +downstreamnt
atggcgggctgctgcgccgcgctggcggccttcctgttcgagtacgacacgccgcgcatc
gtgctcatccgcagccgcaaagtggggctcatgaaccgcgccgtgcaactgctcatcctg
gcctacgtcatcgggtgggtgtttgtgtgggaaaagggctaccaggaaactgactccgtg
gtcagctccgttacgaccaaggtcaagggcgtggctgtgaccaacacttctaaacttgga
ttccggatctgggatgtggcggattatgtgataccagctcaggaggaaaactccctcttc
gtcatgaccaacgtgatcctcaccatgaaccagacacagggcctgtgccccgagattcca
gatgcgaccactgtgtgtaaatcagatgccagctgtactgccggctctgccggcacccac
agcaacggagtctcaacaggcaggtgcgtagctttcaacgggtctgtcaagacgtgtgag
gtggcggcctggtgcccggtggaggatgacacacacgtgccacaacctgcttttttaaag
gctgcagaaaacttcactcttttggttaagaacaacatctggtatcccaaatttaatttc
agcaagaggaatatccttcccaacatcaccactacttacctcaagtcgtgcatttatgat
gctaaaacagatcccttctgccccatattccgtcttggcaaaatagtggagaacgcagga
cacagtttccaggacatggccgtggagggaggcatcatgggcatccaggtcaactgggac
tgcaacctggacagagccgcctccctctgcttgcccaggtactccttccgccgcctcgat
acacgggacgttgagcacaacgtatctcctggctacaatttcaggtttgccaagtactac
agagacctggctggcaacgagcagcgcacgctcatcaaggcctatggcatccgcttcgac
atcattgtgtttgggaaggcagggaaatttgacatcatccccactatgatcaacatcggc
tctggcctggcactgctaggcatggcgaccgtgctgtgtgacatcatagtcctctactgc
atgaagaaaagactctactatcgggagaagaaatataaatatgtggaagattacgagcag
ggtcttgctagtgagctggaccagtga

  All links  
Disease (1)   
   OMIM (1)   
Gene (19)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
Protein sequence (12)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (10)   
DNA sequence (54)   
   RefSeq(nuc) (14)   
   GenBank (20)   
   EMBL (20)   
3D Structure (3)   
   PDB (3)   
Protein domain (2)   
   Pfam (2)   
All databases (91)   

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