KEGG   Homo sapiens (human): 5027
Entry
5027              CDS       T01001                                 
Symbol
P2RX7, P2X7
Name
(RefSeq) purinergic receptor P2X 7
  KO
K05220  P2X purinoceptor 7
Organism
hsa  Homo sapiens (human)
Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04621  NOD-like receptor signaling pathway
Network
nt06528  Calcium signaling
  Element
N01642  Ca2+ entry, Ligand-gated Ca2+ channel
Drug target
Brilliant blue G: D10799<US>
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    5027 (P2RX7)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    5027 (P2RX7)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    5027 (P2RX7)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:hsa04040]
    5027 (P2RX7)
Ion channels [BR:hsa04040]
 Ligand-gated channels
  ATP-gated cation channel (P2X)
   5027 (P2RX7)
SSDB
Motif
Pfam: P2X_receptor P2RX7_C Keratin_matx Ribosomal_L5_C
Other DBs
NCBI-GeneID: 5027
NCBI-ProteinID: NP_002553
OMIM: 602566
HGNC: 8537
Ensembl: ENSG00000089041
UniProt: Q99572
Position
12:121132876..121188032
AA seq 595 aa
MPACCSCSDVFQYETNKVTRIQSMNYGTIKWFFHVIIFSYVCFALVSDKLYQRKEPVISS
VHTKVKGIAEVKEEIVENGVKKLVHSVFDTADYTFPLQGNSFFVMTNFLKTEGQEQRLCP
EYPTRRTLCSSDRGCKKGWMDPQSKGIQTGRCVVYEGNQKTCEVSAWCPIEAVEEAPRPA
LLNSAENFTVLIKNNIDFPGHNYTTRNILPGLNITCTFHKTQNPQCPIFRLGDIFRETGD
NFSDVAIQGGIMGIEIYWDCNLDRWFHHCRPKYSFRRLDDKTTNVSLYPGYNFRYAKYYK
ENNVEKRTLIKVFGIRFDILVFGTGGKFDIIQLVVYIGSTLSYFGLAAVFIDFLIDTYSS
NCCRSHIYPWCKCCQPCVVNEYYYRKKCESIVEPKPTLKYVSFVDESHIRMVNQQLLGRS
LQDVKGQEVPRPAMDFTDLSRLPLALHDTPPIPGQPEEIQLLRKEATPRSRDSPVWCQCG
SCLPSQLPESHRCLEELCCRKKPGACITTSELFRKLVLSRHVLQFLLLYQEPLLALDVDS
TNSRLRHCAYRCYATWRFGSQDMADFAILPSCCRWRIRKEFPKSEGQYSGFKSPY
NT seq 1788 nt   +upstreamnt  +downstreamnt
atgccggcctgctgcagctgcagtgatgttttccagtatgagacgaacaaagtcactcgg
atccagagcatgaattatggcaccattaagtggttcttccacgtgatcatcttttcctac
gtttgctttgctctggtgagtgacaagctgtaccagcggaaagagcctgtcatcagttct
gtgcacaccaaggtgaaggggatagcagaggtgaaagaggagatcgtggagaatggagtg
aagaagttggtgcacagtgtctttgacaccgcagactacaccttccctttgcaggggaac
tctttcttcgtgatgacaaactttctcaaaacagaaggccaagagcagcggttgtgtccc
gagtatcccacccgcaggacgctctgttcctctgaccgaggttgtaaaaagggatggatg
gacccgcagagcaaaggaattcagaccggaaggtgtgtagtgtatgaagggaaccagaag
acctgtgaagtctctgcctggtgccccatcgaggcagtggaagaggccccccggcctgct
ctcttgaacagtgccgaaaacttcactgtgctcatcaagaacaatatcgacttccccggc
cacaactacaccacgagaaacatcctgccaggtttaaacatcacttgtaccttccacaag
actcagaatccacagtgtcccattttccgactaggagacatcttccgagaaacaggcgat
aatttttcagatgtggcaattcagggcggaataatgggcattgagatctactgggactgc
aacctagaccgttggttccatcactgccgtcccaaatacagtttccgtcgccttgacgac
aagaccaccaacgtgtccttgtaccctggctacaacttcagatacgccaagtactacaag
gaaaacaatgttgagaaacggactctgataaaagtcttcgggatccgttttgacatcctg
gtttttggcaccggaggaaaatttgacattatccagctggttgtgtacatcggctcaacc
ctctcctacttcggtctggccgctgtgttcatcgacttcctcatcgacacttactccagt
aactgctgtcgctcccatatttatccctggtgcaagtgctgtcagccctgtgtggtcaac
gaatactactacaggaagaagtgcgagtccattgtggagccaaagccgacattaaagtat
gtgtcctttgtggatgaatcccacattaggatggtgaaccagcagctactagggagaagt
ctgcaagatgtcaagggccaagaagtcccaagacctgcgatggacttcacagatttgtcc
aggctgcccctggccctccatgacacacccccgattcctggacaaccagaggagatacag
ctgcttagaaaggaggcgactcctagatccagggatagccccgtctggtgccagtgtgga
agctgcctcccatctcaactccctgagagccacaggtgcctggaggagctgtgctgccgg
aaaaagccgggggcctgcatcaccacctcagagctgttcaggaagctggtcctgtccaga
cacgtcctgcagttcctcctgctctaccaggagcccttgctggcgctggatgtggattcc
accaacagccggctgcggcactgtgcctacaggtgctacgccacctggcgcttcggctcc
caggacatggctgactttgccatcctgcccagctgctgccgctggaggatccggaaagag
tttccgaagagtgaagggcagtacagtggcttcaagagtccttactga

  All links  
Disease (1)   
   OMIM (1)   
Gene (21)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (79)   
   RefSeq(nuc) (17)   
   GenBank (31)   
   EMBL (31)   
Protein domain (4)   
   Pfam (4)   
All databases (114)   

Download RDF
DBGET integrated database retrieval system