KEGG   Homo sapiens (human): 5046Help
Entry
5046              CDS       T01001                                 

Gene name
PCSK6, PACE4, SPC4
Definition
(RefSeq) proprotein convertase subtilisin/kexin type 6
  KO
K08672  proprotein convertase subtilisin/kexin type 6 [EC:3.4.21.-]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    5046 (PCSK6)
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:hsa03110]
    5046 (PCSK6)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.-  
     5046 (PCSK6)
Peptidases and inhibitors [BR:hsa01002]
 Serine peptidases
  Family S8: subtilisin family
   5046 (PCSK6)
Chaperones and folding catalysts [BR:hsa03110]
 Intramolecular chaperones
  Subtilisin family
   5046 (PCSK6)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Peptidase_S8 P_proprotein S8_pro-domain GF_recep_IV Furin-like_2 PLAC VSP
Motif
Other DBs
NCBI-GeneID: 5046
NCBI-ProteinID: NP_002561
OMIM: 167405
HGNC: 8569
Ensembl: ENSG00000140479
Vega: OTTHUMG00000172097
Pharos: P29122(Tchem)
UniProt: P29122 A2RQD9
Position
15q26.3
AA seq 969 aa AA seqDB search
MPPRAPPAPGPRPPPRAAAATDTAAGAGGAGGAGGAGGPGFRPLAPRPWRWLLLLALPAA
CSAPPPRPVYTNHWAVQVLGGPAEADRVAAAHGYLNLGQIGNLEDYYHFYHSKTFKRSTL
SSRGPHTFLRMDPQVKWLQQQEVKRRVKRQVRSDPQALYFNDPIWSNMWYLHCGDKNSRC
RSEMNVQAAWKRGYTGKNVVVTILDDGIERNHPDLAPNYDSYASYDVNGNDYDPSPRYDA
SNENKHGTRCAGEVAASANNSYCIVGIAYNAKIGGIRMLDGDVTDVVEAKSLGIRPNYID
IYSASWGPDDDGKTVDGPGRLAKQAFEYGIKKGRQGLGSIFVWASGNGGREGDYCSCDGY
TNSIYTISVSSATENGYKPWYLEECASTLATTYSSGAFYERKIVTTDLRQRCTDGHTGTS
VSAPMVAGIIALALEANSQLTWRDVQHLLVKTSRPAHLKASDWKVNGAGHKVSHFYGFGL
VDAEALVVEAKKWTAVPSQHMCVAASDKRPRSIPLVQVLRTTALTSACAEHSDQRVVYLE
HVVVRTSISHPRRGDLQIYLVSPSGTKSQLLAKRLLDLSNEGFTNWEFMTVHCWGEKAEG
QWTLEIQDLPSQVRNPEKQGKLKEWSLILYGTAEHPYHTFSAHQSRSRMLELSAPELEPP
KAALSPSQVEVPEDEEDYTAQSTPGSANILQTSVCHPECGDKGCDGPNADQCLNCVHFSL
GSVKTSRKCVSVCPLGYFGDTAARRCRRCHKGCETCSSRAATQCLSCRRGFYHHQEMNTC
VTLCPAGFYADESQKNCLKCHPSCKKCVDEPEKCTVCKEGFSLARGSCIPDCEPGTYFDS
ELIRCGECHHTCGTCVGPGREECIHCAKNFHFHDWKCVPACGEGFYPEEMPGLPHKVCRR
CDENCLSCAGSSRNCSRCKTGFTQLGTSCITNHTCSNADETFCEMVKSNRLCERKLFIQF
CCRTCLLAG
NT seq 2910 nt NT seq  +upstreamnt  +downstreamnt
atgcctccgcgcgcgccgcctgcgcccgggccccggccgccgccccgggccgccgccgcc
accgacaccgccgcgggcgcggggggcgcggggggcgcggggggcgccggcgggcccggg
ttccggccgctcgcgccgcgtccctggcgctggctgctgctgctggcgctgcctgccgcc
tgctccgcgcccccgccgcgccccgtctacaccaaccactgggcggtgcaagtgctgggc
ggcccggccgaggcggaccgcgtggcggcggcgcacgggtacctcaacttgggccagatt
ggaaacctggaagattactaccatttttatcacagcaaaacctttaaaagatcaaccttg
agtagcagaggccctcacaccttcctcagaatggacccccaggtgaaatggctccagcaa
caggaagtgaaacgaagggtgaagagacaggtgcgaagtgacccgcaggccctttacttc
aacgaccccatttggtccaacatgtggtacctgcattgtggcgacaagaacagtcgctgc
cggtcggaaatgaatgtccaggcagcgtggaagaggggctacacaggaaaaaacgtggtg
gtcaccatccttgatgatggcatagagagaaatcaccctgacctggccccaaattatgat
tcctacgccagctacgacgtgaacggcaatgattatgacccatctccacgatatgatgcc
agcaatgaaaataaacacggcactcgttgtgcgggagaagttgctgcttcagcaaacaat
tcctactgcatcgtgggcatagcgtacaatgccaaaataggaggcatccgcatgctggac
ggcgatgtcacagatgtggtcgaggcaaagtcgctgggcatcagacccaactacatcgac
atttacagtgccagctgggggccggacgacgacggcaagacggtggacgggcccggccga
ctggctaagcaggctttcgagtatggcattaaaaagggccggcagggcctgggctccatt
ttcgtctgggcatctgggaatggcgggagagagggggactactgctcgtgcgatggctac
accaacagcatctacaccatctccgtcagcagcgccaccgagaatggctacaagccctgg
tacctggaagagtgtgcctccaccctggccaccacctacagcagtggggccttttatgag
cgaaaaatcgtcaccacggatctgcgtcagcgctgtaccgatggccacactgggacctca
gtctctgcccccatggtggcgggcatcatcgccttggctctagaagcaaacagccagtta
acctggagggacgtccagcacctgctagtgaagacatcccggccggcccacctgaaagcg
agcgactggaaagtgaacggcgcgggtcataaagttagccatttctatggatttggtttg
gtggacgcagaagctctcgttgtggaggcaaagaagtggacagcagtgccatcgcagcac
atgtgtgtggccgcctcggacaagagacccaggagcatccccttagtgcaggtgctgcgg
actacggccctgaccagcgcctgcgcggagcactcggaccagcgggtggtctacttggag
cacgtggtggttcgcacctccatctcacacccacgccgaggagacctccagatctacctg
gtttctccctcgggaaccaagtctcaacttctggcaaagaggttgctggatctttccaat
gaagggtttacaaactgggaattcatgactgtccactgctggggagaaaaggctgaaggg
cagtggaccttggaaatccaagatctgccatcccaggtccgcaacccggagaagcaaggg
aagttgaaagaatggagcctcatactgtatggcacagcagagcacccgtaccacaccttc
agtgcccatcagtcccgctcgcggatgctggagctctcagccccagagctggagccaccc
aaggctgccctgtcaccctcccaggtggaagttcctgaagatgaggaagattacacagct
caatccaccccaggctctgctaatattttacagaccagtgtgtgccatccggagtgtggt
gacaaaggctgtgatggccccaatgcagaccagtgcttgaactgcgtccacttcagcctg
gggagtgtcaagaccagcaggaagtgcgtgagtgtgtgccccttgggctactttggggac
acagcagcaagacgctgtcgccggtgccacaaggggtgtgagacctgctccagcagagct
gcgacgcagtgcctgtcttgccgccgcgggttctatcaccaccaggagatgaacacctgt
gtgaccctctgtcctgcaggattttatgctgatgaaagtcagaaaaattgccttaaatgc
cacccaagctgtaaaaagtgcgtggatgaacctgagaaatgtactgtctgtaaagaagga
ttcagccttgcacggggcagctgcattcctgactgtgagccaggcacctactttgactca
gagctgatcagatgtggggaatgccatcacacctgcggaacctgcgtggggccaggcaga
gaagagtgcattcactgtgcgaaaaacttccacttccacgactggaagtgtgtgccagcc
tgtggtgagggcttctacccagaagagatgccgggcttgccccacaaagtgtgtcgaagg
tgtgacgagaactgcttgagctgtgcaggctccagcaggaactgtagcaggtgtaagacg
ggcttcacacagctggggacctcctgcatcaccaaccacacgtgcagcaacgctgacgag
acattctgcgagatggtgaagtccaaccggctgtgcgaacggaagctcttcattcagttc
tgctgccgcacgtgcctcctggccgggtaa

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Ontology (4)   
   KEGG BRITE (4)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (44)   
   KEGG ORTHOLOGY (1)   
   RefGene (28)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (8)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (10)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (45)   
   RefSeq(nuc) (9)   
   GenBank (18)   
   EMBL (18)   
Protein domain (7)   
   Pfam (7)   
All databases (112)   

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