KEGG   Homo sapiens (human): 5052
Entry
5052              CDS       T01001                                 

Gene name
PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2
Definition
(RefSeq) peroxiredoxin 1
  KO
K13279  peroxiredoxin 1 [EC:1.11.1.24]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04146  Peroxisome
hsa05146  Amoebiasis
Disease
H02221  Methylmalonic aciduria and homocystinuria
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    5052 (PRDX1)
 09160 Human Diseases
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    5052 (PRDX1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5052 (PRDX1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.24  thioredoxin-dependent peroxiredoxin
     5052 (PRDX1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   5052 (PRDX1)
SSDB
Motif
Pfam: AhpC-TSA Redoxin 1-cysPrx_C SCO1-SenC Endothelin
Other DBs
NCBI-GeneID: 5052
NCBI-ProteinID: NP_001189360
OMIM: 176763
HGNC: 9352
Ensembl: ENSG00000117450
Vega: OTTHUMG00000007738
Pharos: Q06830(Tbio)
UniProt: Q06830 A0A384NPQ2
Structure
PDB: 
4XCS 3HY2 2RII

Position
1p34.1
AA seq 199 aa
MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG
SDTIKPDVQKSKEYFSKQK
NT seq 600 nt   +upstreamnt  +downstreamnt
atgtcttcaggaaatgctaaaattgggcaccctgcccccaacttcaaagccacagctgtt
atgccagatggtcagtttaaagatatcagcctgtctgactacaaaggaaaatatgttgtg
ttcttcttttaccctcttgacttcacctttgtgtgccccacggagatcattgctttcagt
gatagggcagaagaatttaagaaactcaactgccaagtgattggtgcttctgtggattct
cacttctgtcatctagcatgggtcaatacacctaagaaacaaggaggactgggacccatg
aacattcctttggtatcagacccgaagcgcaccattgctcaggattatggggtcttaaag
gctgatgaaggcatctcgttcaggggcctttttatcattgatgataagggtattcttcgg
cagatcactgtaaatgacctccctgttggccgctctgtggatgagactttgagactagtt
caggccttccagttcactgacaaacatggggaagtgtgcccagctggctggaaacctggc
agtgataccatcaagcctgatgtccaaaagagcaaagaatatttctccaagcagaagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (115)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (99)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (44)   
   RefSeq(nuc) (4)   
   GenBank (20)   
   EMBL (20)   
Protein domain (5)   
   Pfam (5)   
All databases (181)   

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