KEGG   Homo sapiens (human): 5052
Entry
5052              CDS       T01001                                 
Symbol
PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2
Name
(RefSeq) peroxiredoxin 1
  KO
K13279  peroxiredoxin 1 [EC:1.11.1.24]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04146  Peroxisome
hsa04980  Cobalamin transport and metabolism
hsa05146  Amoebiasis
Network
nt06538  Cobalamin transport and metabolism
  Element
N01809  Mutation-caused epigenetic silencing of MMACHC
Disease
H02221  Methylmalonic aciduria and homocystinuria
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    5052 (PRDX1)
 09150 Organismal Systems
  09154 Digestive system
   04980 Cobalamin transport and metabolism
    5052 (PRDX1)
 09160 Human Diseases
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    5052 (PRDX1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5052 (PRDX1)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.24  thioredoxin-dependent peroxiredoxin
     5052 (PRDX1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Proteins found in most exosomes
   5052 (PRDX1)
SSDB
Motif
Pfam: AhpC-TSA Redoxin 1-cysPrx_C Endothelin
Other DBs
NCBI-GeneID: 5052
NCBI-ProteinID: NP_001189360
OMIM: 176763
HGNC: 9352
Ensembl: ENSG00000117450
UniProt: Q06830 A0A384NPQ2
Structure
Position
1:complement(45511051..45522890)
AA seq 199 aa
MSSGNAKIGHPAPNFKATAVMPDGQFKDISLSDYKGKYVVFFFYPLDFTFVCPTEIIAFS
DRAEEFKKLNCQVIGASVDSHFCHLAWVNTPKKQGGLGPMNIPLVSDPKRTIAQDYGVLK
ADEGISFRGLFIIDDKGILRQITVNDLPVGRSVDETLRLVQAFQFTDKHGEVCPAGWKPG
SDTIKPDVQKSKEYFSKQK
NT seq 600 nt   +upstreamnt  +downstreamnt
atgtcttcaggaaatgctaaaattgggcaccctgcccccaacttcaaagccacagctgtt
atgccagatggtcagtttaaagatatcagcctgtctgactacaaaggaaaatatgttgtg
ttcttcttttaccctcttgacttcacctttgtgtgccccacggagatcattgctttcagt
gatagggcagaagaatttaagaaactcaactgccaagtgattggtgcttctgtggattct
cacttctgtcatctagcatgggtcaatacacctaagaaacaaggaggactgggacccatg
aacattcctttggtatcagacccgaagcgcaccattgctcaggattatggggtcttaaag
gctgatgaaggcatctcgttcaggggcctttttatcattgatgataagggtattcttcgg
cagatcactgtaaatgacctccctgttggccgctctgtggatgagactttgagactagtt
caggccttccagttcactgacaaacatggggaagtgtgcccagctggctggaaacctggc
agtgataccatcaagcctgatgtccaaaagagcaaagaatatttctccaagcagaagtga

  All links  
Disease (2)   
   OMIM (2)   
Gene (112)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (99)   
   OC (1)   
Protein sequence (7)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (44)   
   RefSeq(nuc) (4)   
   GenBank (20)   
   EMBL (20)   
3D Structure (14)   
   PDB (14)   
Protein domain (4)   
   Pfam (4)   
All databases (183)   

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