KEGG   Homo sapiens (human): 50944Help
Entry
50944             CDS       T01001                                 

Gene name
SHANK1, SPANK-1, SSTRIP, synamon
Definition
(RefSeq) SH3 and multiple ankyrin repeat domains 1
  KO
K15009  SH3 and multiple ankyrin repeat domains protein
Organism
hsa  Homo sapiens (human)
Pathway
hsa04724  Glutamatergic synapse
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    50944 (SHANK1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Ank_2 Ank_4 SAM_1 Ank_5 Ank SH3_2 Ank_3 SAM_2 PDZ_6 SH3_1 PDZ SH3_9 FERM_f0 SAM_PNT
Motif
Other DBs
NCBI-GeneID: 50944
NCBI-ProteinID: NP_057232
OMIM: 604999
HGNC: 15474
Ensembl: ENSG00000161681
Vega: OTTHUMG00000137380
Pharos: Q9Y566(Tbio)
UniProt: Q9Y566
Structure
PDB: 

Position
19q13.33
AA seq 2161 aa AA seqDB search
MTHSPATSEDEERHSASECPEGGSESDSSPDGPGRGPRGTRGQGSGAPGSLASVRGLQGR
SMSVPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLF
QPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGL
KKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTEGSVEVIRTLCLGGAHI
DFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELL
LFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKE
TCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARR
RGPPGTGLTVPPALLRANSDTSMALPDWMVFSAPGAASSGAPGPTSGSQGQSQPSAPTTK
LSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPREGPAGGTGGSGGPGGS
LGSRGRRRKLYSAVPGRSFMAVKSYQAQAEGEISLSKGEKIKVLSIGEGGFWEGQVKGRV
GWFPSDCLEEVANRSQESKQESRSDKAKRLFRHYTVGSYDSFDAPSLMDGIGPGSDYIIK
EKTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGD
FLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDEAVHKKAPQQAKRLPPP
TISLRSKSMTSELEEMEYEQQPAPVPSMEKKRTVYQMALNKLDEILAAAQQTISASESPG
PGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPY
LAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGG
PLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHP
PHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGP
ALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQP
PPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSP
APAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLST
DAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAY
GGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRP
PSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAA
RRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQP
RAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGE
FLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDST
ASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDS
RSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGS
STPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLAL
RACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQA
SALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQ
RQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTST
RHLQGVEFEMRPPLLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPT
GGAGGSADPFAPVFVPPHPGISGGLGGALSGASRSLSPTRLLSLPPDKPFGAKPLGFWTK
FDVADWLEWLGLAEHRAQFLDHEIDGSHLPALTKEDYVDLGVTRVGHRMNIDRALKFFLE
R
NT seq 6486 nt NT seq  +upstreamnt  +downstreamnt
atgacccacagccccgcgacaagcgaggacgaggaacgccacagtgccagcgagtgtccc
gaggggggctcagagtccgacagctccccagacgggccaggtcgaggcccccgggggacc
cggggccagggcagtggggcacctggtagcctggcctctgttagaggcctccagggccgc
tcaatgtccgtcccagacgacgcccacttcagcatgatggtcttcaggattggcatcccg
gacctgcaccagacaaaatgccttcgcttcaaccccgatgccaccatctggacggccaag
cagcaggtgctctgtgccctgagcgagagcctgcaggatgtgctcaactatggcctgttc
caaccggccacctccggccgcgatgccaacttcctggaggaggagaggctgctgcgggag
tacccccagtcctttgagaagggggtcccctacctggagttccgatacaagacccgagtt
tacaaacagaccaacctggatgagaagcagctggccaagttgcacacgaagacggggttg
aagaagttcctggagtatgtgcagctcgggacatctgacaaggtggcgcggctgctggac
aaggggctggaccccaattaccatgactcggattcgggagagacccccttgacactggcg
gcccagaccgaaggctctgtagaggtgattcgaaccctgtgcctgggcggggcccacatt
gacttccgggcccgggatggcatgaccgcactgcataaggccgcatgcgcccgacactgc
ctggcactcacggcgctcctggaccttgggggttcccccaactacaaggaccgtcggggg
ctgacccctctgttccacacggccatggtgggtggtgacccccgatgctgcgagctgctc
ctgttcaacagggcccagctgggcatagctgatgagaacggctggcaggaaatccaccag
gcctgccagcggggtcactctcagcacctggagcatctgcttttctacggggctgagcct
ggagcccagaacgcctcggggaacacggctctgcacatctgcgccctctacaacaaggag
acctgtgccaggatcctcctgtatcgaggtgccgacaaggatgtgaagaacaacaacgga
cagacccccttccaggtggcagtgattgctgggaattttgagctgggggagctgatccga
aaccaccgagaacaggatgtggtgcccttccaggagtcccccaagtacgcggcccggcga
cgggggcccccaggcacagggctgacggtgcccccggcgctgctgcgggccaacagtgac
accagcatggcgctgcccgactggatggtgttctccgccccgggggccgcgtcctctggg
gcccctggccctacctcagggtcccagggccagtcgcagccctcggcccccaccaccaag
ctcagcagcgggaccctccgaagtgccagcagcccccggggtgccagggcccgctctcca
tcccgagggaggcaccctgaggacgccaagaggcagccccgaggccggcccagctccagc
gggacaccccgggaagggccagccgggggcacggggggctcagggggccccgggggctcc
ctgggcagccgcgggaggcggaggaagctctactcagcggtacccggacgctccttcatg
gctgtgaagtcctaccaggcccaagccgagggggagatctccctgagcaagggcgagaag
atcaaagtacttagcatcggggaaggaggcttctgggaaggccaggtcaaaggtcgtgtt
ggctggttcccctctgactgcctggaagaagtggcgaatcgctctcaggagagcaagcaa
gaaagccgcagtgacaaggcaaagagactcttccggcattataccgtgggctcctacgac
agctttgatgccccaagcttaatggatgggattggcccagggagcgattacatcattaag
gagaagacagtcttgctgcagaagaaggacagtgaggggtttgggttcgtgctccggggg
gccaaggcgcagacccccatcgaggagttcacccccaccccggccttcccggcgctgcag
tacctggagtcggtggacgagggtggcgtggcatggcgagctggactgcgaatgggagac
ttcctcatcgaggtgaacgggcagaatgtggtgaaggtcggccaccgacaggtggtgaac
atgatccgccaagggggcaacacgctgatggtgaaggtggtgatggtcaccaggcacccg
gacatggatgaggcagtgcacaagaaagcaccccagcaggccaagcggctgccgccccca
accatctccctgcgttccaaatctatgacctcagagctggaggagatggagtacgagcag
cagccggcgccggtgcccagcatggagaaaaagcggaccgtgtatcagatggctctcaac
aaactggacgaaatcctggccgcagctcaacagaccatcagtgcaagcgaaagccctggt
cccggtggcctcgcgtccctgggcaaacaccgacccaaaggtttctttgccactgagtcg
agcttcgatccccaccaccgtgcccagccaagttacgagcgtccttctttcctgcctcca
ggacctgggttgatgctccggcaaaaatctatcggtgcggcagaagatgacagaccttac
ctagcacccccagccatgaaattcagccgcagcctgtctgtgcctggttcggaggacatt
cccccgccacccaccacgtccccaccggagcctccctacagcacacctccagtcccctcc
tcctcagggcgcctcaccccctcccctcggggagggcccttcaaccctggctctggtggc
cccctccccgcctcctcccctgcatcctttgacgggccctcccctcccgacactcgcgtg
gggagccgcgagaagagcctgtaccacagtgggcccctgcccccggcccaccaccacccg
ccccaccaccaccaccaccacgccccgccccctcagccccaccaccaccacgcccacccc
cctcatcctcccgagatggagacaggcggctctcccgacgaccctccaccccgcctggct
ctggggccccagcccagcctgcgaggctggaggggcggcgggcccagcccgaccccgggg
gccccgtccccatcgcaccacggcagcgcgggcgggggcggcggctcctcccagggcccg
gctctacgctatttccagctgcccccgcgggcggccagcgcagccatgtacgtgcccgcc
cgctcgggccgcggccgcaagggcccgctggtcaagcagaccaaggtggaaggcgagccc
cagaagggcggcggcctcccgcccgcgccgtcgcccacgtccccggcctccccgcagccg
ccgcccgccgtggccgcgccctcggagaagaactccatccccatccccaccatcatcatc
aaggccccgtccaccagtagcagcggccgcagcagccagggcagcagcaccgaggcggag
ccccccacccagccggagcccacgggaggcggcggcggcggcggctcctcgcccagcccc
gccccggccatgtcacccgtgcccccgtccccctcgcccgtgcccacccccgcctcgccc
agcggcccggccacgctggacttcacgagccagttcggggccgccctggtgggggcggcc
cggagggaggggggctggcagaatgaggcgcgccggcgctccacgctgttcctgtccacc
gacgcgggggacgaggacggcggggacggcgggctgggcacaggggcggccccgggcccg
cggctgcgccactccaaatccatcgacgagggcatgttctccgccgagccctacctccga
ctggagtctgcgggcagcggcgcgggctacggcggctacggggccggtagccgagcctac
gggggtggcgggggcagcagcgccttcaccagcttcctgcccccgcgacccctggtgcac
ccgctgaccggcaaggccctggatcccgcctccccgctggggctggccctggccgcccgc
gagcgagcgctgaaggagtcctcggagggcggcggggccccccagccgcctcccaggccc
ccatcgccccgctacgaggccccgccgcccaccccgcaccaccactcgccccacgcccac
cacgagccagtgctgcgtctctggggggcctccccgccggaccctgcgcgccgggagctg
gggtacagggccgggctgggcagccaggagaagtcccttcccgccagcccgcccgccgcc
cggcgttccctgctacaccgcctgccgcccaccgctcccggggtggggcccctcctgctg
cagctggggacggagcccccggccccgcaccccggagtaagcaagccctggaggtccgca
gcccccgaagaacccgagcggctgccgctgcacgtgcggttccttgaaaactgccagccc
cgggcccctgtgacgagcggaaggggtcccccctcggaggacgggccgggggtcccgccg
cccagcccacgccggtccgtgcccccctccccgacctccccgagggccagcgaagagaac
gggctgcccctgctggtcctgccgcctcccgccccctcggtggatgtggaagatggcgaa
ttccttttcgtggaaccgctgcctccgcctctggaattctccaacagcttcgaaaagcca
gagtcgcccctcacgcctgggcctccccacccgctgcccgacacacctgcccctgccacc
ccgttaccccctgtgccacccccggctgtggccgcagcccctcccaccctggactccacc
gcatccagcctgacatcctatgacagcgaggtggccaccctgacccagggggcctccgcc
gctcctggggacccccatccaccaggcccgcctgccccagcagcaccggctcccgctgcc
ccacagcctggcccggaccctccgcctggcacggattctggcatcgaggaggtggacagt
cggagcagcagtgaccacccactggagaccatcagcagcgcctccacgctgagcagccta
tctgccgaaggtggtggcagcgcagggggtgggggcggggctggggccggtgtggccagt
gggccggagcttctggacacctatgtggcctacctggacggccaggcctttgggggcagc
agtactcccggcccgccataccctcctcagctcatgactccctctaagctccggggccgg
gcgctaggagccagcggaggcctgcggcctggccccagcgggggactccgagaccctgtt
acccccaccagccccaccgtctcggtgacaggggctggaaccgatgggctgctggccctg
cgtgcttgttcaggaccccccacggcaggcgtggcggggggtccggtggctgtagagcca
gaagtcccaccggtgcccttgccgacggcctcctctctgccccggaagctgctgccctgg
gaggagggcccgggcccaccgccaccacctctgcccgggcccttggcccagcctcaggcc
tcagccttggccacagtaaaagccagcatcatcagtgaactcagctccaagcttcagcag
tttgggggctcctcggcagctggcggcgctctgccctgggcccgaggaggcagtggggga
ggcggagacagccaccacgggggagccagctatgtccccgagaggacctcctccctgcag
cggcagagactctccgacgactcccagtcctcactcctctccaagcctgtcagcagcctg
tttcagaactggcccaaaccacctctgccgccactccccaccggaacaggggtctcccct
acagccgctgcggccccaggggccacctcaccctcagcctcctcctcctccacgtccacc
cgccacctccagggcgtggagttcgagatgcggccccctctgctccgccgggcccccagc
ccctcgctgctgcccgcctcggagcacaaggtcagccctgcgcccaggccctcgtccctg
cccatcctgccttccggacccctctacccaggcctctttgacatccgtggctccccaact
ggaggggcaggaggctcggctgaccccttcgccccagtctttgtgccgccacacccgggg
atatccggggggctcgggggagccttgtcaggggcctcgcgctccctctcaccgacccgc
ctgctctcgctgcccccggacaagccgtttggcgctaaacctctggggttctggaccaag
ttcgacgtggctgattggctggagtggctgggtttggcggagcaccgagcccagttcctg
gaccacgagatcgatggctcccacctgcccgccttgaccaaggaggactacgtcgatcta
ggtgtgaccagggtgggccaccgcatgaacatcgaccgggctctcaaattcttcctggag
aggtga

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Ontology (1)   
   KEGG BRITE (1)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (95)   
   KEGG ORTHOLOGY (1)   
   RefGene (83)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (4)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (13)   
   RefSeq(nuc) (3)   
   GenBank (5)   
   EMBL (5)   
Protein domain (14)   
   Pfam (14)   
All databases (131)   

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