KEGG   Homo sapiens (human): 51004
Entry
51004             CDS       T01001                                 
Symbol
COQ6, CGI-10, CGI10, COQ10D6
Name
(RefSeq) coenzyme Q6, monooxygenase
  KO
K06126  4-hydroxy-3-polyprenylbenzoate 5-hydroxylase / 2-methoxy-6-polyprenylphenol 4-hydroxylase [EC:1.14.15.45 1.14.15.46]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00130  Ubiquinone and other terpenoid-quinone biosynthesis
hsa01100  Metabolic pathways
hsa01240  Biosynthesis of cofactors
Module
hsa_M00128  Ubiquinone biosynthesis, eukaryotes, 4-hydroxybenzoate + polyprenyl-PP => ubiquinone
Disease
H00999  Coenzyme Q10 deficiency
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00130 Ubiquinone and other terpenoid-quinone biosynthesis
    51004 (COQ6)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.45  4-hydroxy-3-polyprenylbenzoate 5-hydroxylase
     51004 (COQ6)
    1.14.15.46  2-methoxy-6-polyprenylphenol 4-hydroxylase
     51004 (COQ6)
SSDB
Motif
Pfam: FAD_binding_3 SE
Other DBs
NCBI-GeneID: 51004
NCBI-ProteinID: NP_872282
OMIM: 614647
HGNC: 20233
Ensembl: ENSG00000119723
UniProt: Q9Y2Z9
Position
14:73949918..73963670
AA seq 468 aa
MAARLVSRCGAVRAAPHSGPLVSWRRWSGASTDTVYDVVVSGGGLVGAAMACALGYDIHF
HDKKILLLEAGPKKVLEKLSETYSNRVSSISPGSATLLSSFGAWDHICNMRYRAFRRMQV
WDACSEALIMFDKDNLDDMGYIVENDVIMHALTKQLEAVSDRVTVLYRSKAIRYTWPCPF
PMADSSPWVHITLGDGSTFQTKLLIGADGHNSGVRQAVGIQNVSWNYDQSAVVATLHLSE
ATENNVAWQRFLPSGPIALLPLSDTLSSLVWSTSHEHAAELVSMDEEKFVDAVNSAFWSD
ADHTDFIDTAGAMLQYAVSLLKPTKVSARQLPPSVARVDAKSRVLFPLGLGHAAEYVRPR
VALIGDAAHRVHPLAGQGVNMGFGDISSLAHHLSTAAFNGKDLGSVSHLTGYETERQRHN
TALLAATDLLKRLYSTSASPLVLLRTWGLQATNAVSPLKEQIMAFASK
NT seq 1407 nt   +upstreamnt  +downstreamnt
atggcggcccggcttgtcagccgatgcggggctgtgcgtgcagctccccacagcggcccg
ctggtgtcctggcgcaggtggtccggcgcctcaacagacaccgtgtatgacgtggtggtg
tcgggtggaggcctggtgggcgctgccatggcctgtgccttgggatatgatattcacttt
catgacaagaaaatcctgttgctcgaagcaggtccaaagaaagtactggagaaattgtca
gaaacttacagcaacagggtcagctccatttcccctggctctgcaacgcttctcagtagt
tttggtgcctgggaccatatctgcaacatgagatacagagcctttcggcgaatgcaggtg
tgggacgcctgctcagaggccctgataatgtttgataaggataatttagatgacatgggc
tatatcgtggagaatgatgtcatcatgcatgctctcactaagcagttggaggctgtgtct
gaccgagtgacggttctctacaggagcaaagccattcgctatacctggccttgtccattt
cctatggccgactccagcccttgggttcatattaccctaggtgatggcagcaccttccag
accaaattgttgataggtgcagatggtcacaactccggagtacggcaggctgttggaatc
cagaatgtgagctggaactatgaccagtctgctgttgtggctactctgcatttatcagag
gccacagaaaacaacgtagcctggcagagatttcttccctctgggcctattgctctgctc
ccgctctcagacaccttgagttccttggtttggtccacgtcccatgaacatgcagcagag
ctagttagcatggatgaggaaaaatttgtggatgccgttaactctgccttttggagtgat
gctgaccacacggacttcatcgacacagctggtgccatgctgcagtatgctgtcagcctt
ctgaagcccactaaggtctcggctcgccagctgcccccaagcgtagccagggtggatgcc
aaaagccgagttctgtttcctcttgggttgggacatgctgctgagtacgtcaggcctcgg
gtggcgctcattggggatgcagcccacagagtccatccgcttgcaggacagggtgtcaac
atgggctttggggatatctccagcttggcccatcacctcagtacggcagccttcaatggg
aaggacttaggttccgtgagccacctcacaggttatgaaacagaaagacagcgtcacaac
actgctcttctggctgctacagacttactaaaaaggctctattctaccagtgcctccccg
cttgtgttgctcaggacgtggggcttgcaggccacaaatgcagtgtctccactcaaagaa
cagattatggcctttgcaagcaaatga

  All links  
Disease (2)   
   OMIM (2)   
Gene (10)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (15)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (13)   
DNA sequence (53)   
   RefSeq(nuc) (17)   
   GenBank (18)   
   EMBL (18)   
Protein domain (2)   
   Pfam (2)   
All databases (82)   

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