KEGG   Homo sapiens (human): 51013
Entry
51013             CDS       T01001                                 
Symbol
EXOSC1, CGI-108, CSL4, Csl4p, PCH1F, SKI4, Ski4p, p13
Name
(RefSeq) exosome component 1
  KO
K07573  exosome complex component CSL4
Organism
hsa  Homo sapiens (human)
Pathway
hsa03018  RNA degradation
Disease
H00897  Pontocerebellar hypoplasia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    51013 (EXOSC1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:hsa03019]
    51013 (EXOSC1)
Messenger RNA biogenesis [BR:hsa03019]
 Eukaryotic type
  mRNA degradation factors
   3'-5' decay
    Core exosome factors
     51013 (EXOSC1)
 Prokaryotic type
  Archeal mRNA degradation factors
   Exosome components
    Core exosome
     51013 (EXOSC1)
SSDB
Motif
Pfam: EXOSC1 ECR1_N RRP4_S1 Nairovirus_NSm
Other DBs
NCBI-GeneID: 51013
NCBI-ProteinID: NP_057130
OMIM: 606493
HGNC: 17286
Ensembl: ENSG00000171311
UniProt: Q9Y3B2
Structure
Position
10:complement(97435909..97446006)
AA seq 195 aa
MAPPVRYCIPGERLCNLEEGSPGSGTYTRHGYIFSSLAGCLMKSSENGALPVVSVVRETE
SQLLPDVGAIVTCKVSSINSRFAKVHILYVGSMPLKNSFRGTIRKEDVRATEKDKVEIYK
SFRPGDIVLAKVISLGDAQSNYLLTTAENELGVVVAHSESGIQMVPISWCEMQCPKTHTK
EFRKVARVQPEFLQT
NT seq 588 nt   +upstreamnt  +downstreamnt
atggcgccacctgtgagatactgcatccccggcgaacgtctgtgtaacttggaggagggc
agcccgggcagcggcacctacacccgccacggctacatcttttcgtcgcttgccggctgt
ctgatgaagagcagcgagaatggcgcgcttccagtggtgtctgtagtgagagaaacagag
tcccagttactgccagatgtgggagctattgtaacctgtaaggtctctagcatcaattca
cgctttgccaaagtacacatcctgtatgtggggtccatgcctcttaagaactcttttcga
ggaactatccgcaaggaagatgtccgagcaactgaaaaagacaaggttgaaatttataag
agtttccgcccaggtgacattgtcttggccaaagtgatctccttaggtgatgcacagtcc
aactacctgctaaccaccgccgagaacgagctgggagtggtggtagcccacagtgagtca
ggtatccagatggttcccatcagctggtgtgagatgcagtgccctaagacccacactaaa
gaattccggaaagtagcccgagtacaacccgaattcttgcagacctaa

  All links  
Disease (2)   
   OMIM (2)   
Gene (13)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (10)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (8)   
DNA sequence (38)   
   RefSeq(nuc) (10)   
   GenBank (14)   
   EMBL (14)   
3D Structure (8)   
   PDB (8)   
Protein domain (4)   
   Pfam (4)   
All databases (75)   

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