KEGG   Homo sapiens (human): 51102
Entry
51102             CDS       T01001                                 
Symbol
MECR, CGI-63, DYTOABG, ETR1, FASN2B, NRBF1, OPA16
Name
(RefSeq) mitochondrial trans-2-enoyl-CoA reductase
  KO
K07512  mitochondrial enoyl-[acyl-carrier protein] reductase / trans-2-enoyl-CoA reductase [EC:1.3.1.- 1.3.1.38]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00061  Fatty acid biosynthesis
hsa00062  Fatty acid elongation
hsa01100  Metabolic pathways
hsa01212  Fatty acid metabolism
Module
hsa_M00085  Fatty acid elongation in mitochondria
hsa_M00873  Fatty acid biosynthesis in mitochondria, animals
Disease
H00831  Primary dystonia
H01020  Optic atrophy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    51102 (MECR)
   00062 Fatty acid elongation
    51102 (MECR)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.3  Acting on the CH-CH group of donors
   1.3.1  With NAD+ or NADP+ as acceptor
    1.3.1.38  trans-2-enoyl-CoA reductase (NADPH)
     51102 (MECR)
SSDB
Motif
Pfam: ADH_zinc_N ADH_N ADH_zinc_N_2 PALP
Other DBs
NCBI-GeneID: 51102
NCBI-ProteinID: NP_057095
OMIM: 608205
HGNC: 19691
Ensembl: ENSG00000116353
UniProt: Q9BV79
Structure
Position
1:complement(29167696..29230934)
AA seq 373 aa
MWVCSTLWRVRTPARQWRGLLPASGCHGPAASSYSASAEPARVRALVYGHHGDPAKVVEL
KNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVT
GLKPGDWVIPANAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQ
LQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEHVITEE
ELRRPEMKNFFKDMPQPRLALNCVGGKSSTELLRQLARGGTMVTYGGMAKQPVVASVSLL
IFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSQVPLQDYQSALEAS
MKPFISSKQILTM
NT seq 1122 nt   +upstreamnt  +downstreamnt
atgtgggtctgcagtaccctgtggcgggtgcgaacccccgcccggcagtggcgggggctg
ctcccagcttctggctgtcacggacctgccgcctcctcctactccgcatccgccgagcct
gcccgggtccgggcgcttgtctatgggcaccacggggatccagccaaggtcgtcgaactc
aagaacctggagctagctgctgtgagaggatcagatgtccgtgtgaagatgctggcggcc
cctatcaatccatctgacataaatatgatccaaggaaactacggattccttcctgaactg
cctgctgttggagggaacgaaggtgttgcacaggtggtagcggtgggcagcaatgtgacc
gggctgaagccaggagactgggtgattccagcaaatgctggtttaggaacctggcggacc
gaggctgtgttcagcgaggaagcactgatccaagttccgagtgacatccctcttcagagc
gctgccaccctgggtgtcaatccctgcacagcctacaggatgttgatggacttcgagcaa
ctgcagccaggggattctgtcatccagaatgcatccaacagcggagtggggcaagcagtc
atccagatcgccgcagccctgggcctaagaaccatcaatgtggtccgagacagacctgat
atccagaagctgagtgacagactgaagagtctgggggctgagcatgtcatcacagaagag
gagctaagaaggcccgaaatgaaaaacttctttaaggacatgccccagccacggcttgct
ctcaactgtgttggtgggaaaagctccacagagctgctgcggcagttagcgcgtggagga
accatggtaacctatggggggatggccaagcagcccgtcgtagcctctgtgagcctgctc
atttttaaggatctcaaacttcgaggcttttggttgtcccagtggaagaaggatcacagt
ccagaccagttcaaggagctgatcctcacactgtgcgatctcatccgccgaggccagctc
acagcccctgcctgctcccaggtcccgctgcaggactaccagtctgccttggaagcctcc
atgaagcccttcatatcttcaaagcagattctcaccatgtga

  All links  
Disease (3)   
   OMIM (3)   
Gene (21)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (6)   
   OC (1)   
Protein sequence (25)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (23)   
DNA sequence (57)   
   RefSeq(nuc) (33)   
   GenBank (12)   
   EMBL (12)   
3D Structure (4)   
   PDB (4)   
Protein domain (4)   
   Pfam (4)   
All databases (114)   

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