KEGG   Homo sapiens (human): 51181
Entry
51181             CDS       T01001                                 
Symbol
DCXR, DCR, HCR2, HCRII, KIDCR, P34H, PNTSU, SDR20C1, XR
Name
(RefSeq) dicarbonyl and L-xylulose reductase
  KO
K03331  L-xylulose reductase [EC:1.1.1.10]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00040  Pentose and glucuronate interconversions
hsa01100  Metabolic pathways
Module
hsa_M00014  Glucuronate pathway (uronate pathway)
Disease
H01065  Pentosuria
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    51181 (DCXR)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.10  L-xylulose reductase
     51181 (DCXR)
SSDB
Motif
Pfam: adh_short_C2 adh_short SDR KR Epimerase Shikimate_DH ADH_zinc_N NAD_binding_10 AdoHcyase_NAD RmlD_sub_bind NAD_binding_7 2-Hacid_dh_C DUF3742 DUF1776
Other DBs
NCBI-GeneID: 51181
NCBI-ProteinID: NP_057370
OMIM: 608347
HGNC: 18985
Ensembl: ENSG00000169738
UniProt: Q7Z4W1 A0A384NY14
Structure
Position
17:complement(82035858..82037697)
AA seq 244 aa
MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVD
LGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVAR
GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT
VVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG
FWAC
NT seq 735 nt   +upstreamnt  +downstreamnt
atggagctgttcctcgcgggccgccgggtgctggtcaccggggcaggcaaaggtataggg
cgcggcacggtccaggcgctgcacgcgacgggcgcgcgggtggtggctgtgagccggact
caggcggatcttgacagccttgtccgcgagtgcccggggatagaacccgtgtgcgtggac
ctgggtgactgggaggccaccgagcgggcgctgggcagcgtgggccccgtggacctgctg
gtgaacaacgccgctgtcgccctgctgcagcccttcctggaggtcaccaaggaggccttt
gacagatcctttgaggtgaacctgcgtgcggtcatccaggtgtcgcagattgtggccagg
ggcttaatagcccggggagtcccaggggccatcgtgaatgtctccagccagtgctcccag
cgggcagtaactaaccatagcgtctactgctccaccaagggtgccctggacatgctgacc
aaggtgatggccctagagctcgggccccacaagatccgagtgaatgcagtaaaccccaca
gtggtgatgacgtccatgggccaggccacctggagtgacccccacaaggccaagactatg
ctgaaccgaatcccacttggcaagtttgctgaggtagagcacgtggtgaacgccatcctc
tttctgctgagtgaccgaagtggcatgaccacgggttccactttgccggtggaagggggc
ttctgggcctgctga

  All links  
Disease (2)   
   OMIM (2)   
Gene (15)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (34)   
   RefSeq(nuc) (2)   
   GenBank (16)   
   EMBL (16)   
3D Structure (3)   
   PDB (3)   
Protein domain (14)   
   Pfam (14)   
All databases (73)   

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