KEGG   Homo sapiens (human): 51181
Entry
51181             CDS       T01001                                 

Gene name
DCXR, DCR, HCR2, HCRII, KIDCR, P34H, PNTSU, SDR20C1, XR
Definition
(RefSeq) dicarbonyl and L-xylulose reductase
  KO
K03331  L-xylulose reductase [EC:1.1.1.10]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00040  Pentose and glucuronate interconversions
hsa01100  Metabolic pathways
Module
hsa_M00014  Glucuronate pathway (uronate pathway)
Disease
H01065  Pentosuria
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    51181 (DCXR)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.10  L-xylulose reductase
     51181 (DCXR)
SSDB
Motif
Pfam: adh_short_C2 adh_short KR Epimerase Shikimate_DH ADH_zinc_N DUF3742 NAD_binding_10 RmlD_sub_bind AdoHcyase_NAD DUF1776 NAD_binding_7 2-Hacid_dh_C
Other DBs
NCBI-GeneID: 51181
NCBI-ProteinID: NP_057370
OMIM: 608347
HGNC: 18985
Ensembl: ENSG00000169738
Vega: OTTHUMG00000178483
Pharos: Q7Z4W1(Tbio)
UniProt: Q7Z4W1 A0A384NY14
Structure
PDB: 
3D3W 1PR9 1WNT

Position
17q25.3
AA seq 244 aa
MELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEPVCVD
LGDWEATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVAR
GLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPT
VVMTSMGQATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG
FWAC
NT seq 735 nt   +upstreamnt  +downstreamnt
atggagctgttcctcgcgggccgccgggtgctggtcaccggggcaggcaaaggtataggg
cgcggcacggtccaggcgctgcacgcgacgggcgcgcgggtggtggctgtgagccggact
caggcggatcttgacagccttgtccgcgagtgcccggggatagaacccgtgtgcgtggac
ctgggtgactgggaggccaccgagcgggcgctgggcagcgtgggccccgtggacctgctg
gtgaacaacgccgctgtcgccctgctgcagcccttcctggaggtcaccaaggaggccttt
gacagatcctttgaggtgaacctgcgtgcggtcatccaggtgtcgcagattgtggccagg
ggcttaatagcccggggagtcccaggggccatcgtgaatgtctccagccagtgctcccag
cgggcagtaactaaccatagcgtctactgctccaccaagggtgccctggacatgctgacc
aaggtgatggccctagagctcgggccccacaagatccgagtgaatgcagtaaaccccaca
gtggtgatgacgtccatgggccaggccacctggagtgacccccacaaggccaagactatg
ctgaaccgaatcccacttggcaagtttgctgaggtagagcacgtggtgaacgccatcctc
tttctgctgagtgaccgaagtggcatgaccacgggttccactttgccggtggaagggggc
ttctgggcctgctga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (2)   
   KEGG MODULE (1)   
Disease (3)   
   KEGG DISEASE (1)   
   OMIM (2)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (34)   
   RefSeq(nuc) (2)   
   GenBank (16)   
   EMBL (16)   
Protein domain (13)   
   Pfam (13)   
All databases (86)   

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