KEGG   Homo sapiens (human): 51292
Entry
51292             CDS       T01001                                 

Gene name
GMPR2, GMPR_2
Definition
(RefSeq) guanosine monophosphate reductase 2
  KO
K00364  GMP reductase [EC:1.7.1.7]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00230  Purine metabolism
hsa01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    51292 (GMPR2)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.7  Acting on other nitrogenous compounds as donors
   1.7.1  With NAD+ or NADP+ as acceptor
    1.7.1.7  GMP reductase
     51292 (GMPR2)
SSDB
Motif
Pfam: IMPDH FMN_dh Aldolase Glu_synthase QRPTase_C dCache_3
Other DBs
NCBI-GeneID: 51292
NCBI-ProteinID: NP_001002000
OMIM: 610781
HGNC: 4377
Ensembl: ENSG00000100938
Vega: OTTHUMG00000171912
Pharos: Q9P2T1(Tbio)
UniProt: Q9P2T1
Structure
PDB: 
2C6Q 2BZN 2A7R

Position
14q12
AA seq 348 aa
MPHIDNDVKLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGT
FEMAKVLCKFSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAI
PQVKYICLDVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGI
GPGSVCTTRKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVM
LGGMLAGHSESGGELIERDGKKYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVEVPFKGD
VEHTIRDILGGIRSTCTYVGAAKLKELSRRTTFIRVTQQVNPIFSEAC
NT seq 1047 nt   +upstreamnt  +downstreamnt
atgcctcatattgacaacgatgtgaaactggacttcaaggatgtccttttgaggcccaaa
cgcagtacccttaagtctcgaagtgaggtggatctcacaagatccttttcatttcggaac
tcaaagcagacatactctggggttcccatcattgctgccaatatggatactgtgggcacc
tttgagatggccaaggttctctgtaagttctctctcttcactgctgtccataagcactat
agcctcgttcagtggcaagagtttgctggccagaatcctgactgtcttgagcatctggct
gccagctcaggcacaggctcttctgactttgagcagctggaacagatcctggaagctatt
ccccaggtgaagtatatatgcctggatgtggcaaatggctactctgaacactttgttgaa
tttgtaaaagatgtacggaagcgcttcccccagcacaccatcatggcagggaatgtggta
acaggagagatggtagaagagctcatcctttctggggctgacatcatcaaagtgggaatt
gggccaggctctgtgtgtactactcggaagaaaactggagtggggtatccacagctcagc
gcagtgatggagtgtgcagatgctgctcatggcctcaaaggccacatcatttcagatgga
ggttgcagctgtcctggggatgtggccaaggcttttggggcaggagctgacttcgtgatg
ctgggtggcatgctggctgggcacagtgagtcaggtggtgagctcatcgagagggatggc
aagaagtacaagctcttctatggaatgagttctgaaatggccatgaagaagtatgctggg
ggcgtggctgagtacagagcctcagagggaaagacagtggaagttccttttaaaggagat
gtggaacataccatccgagacatcctaggagggatccgctctacgtgtacctatgtggga
gcagctaagctcaaagagttgagcaggagaactaccttcatccgagtcacccagcaggtg
aatccaatcttcagtgaggcgtgctag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   OMIM (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (4)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (51)   
   RefSeq(nuc) (13)   
   GenBank (19)   
   EMBL (19)   
Protein domain (6)   
   Pfam (6)   
All databases (112)   

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