KEGG   Homo sapiens (human): 51478
Entry
51478             CDS       T01001                                 
Symbol
HSD17B7, PRAP, SDR37C1
Name
(RefSeq) hydroxysteroid 17-beta dehydrogenase 7
  KO
K13373  17beta-estradiol 17-dehydrogenase / 3beta-hydroxysteroid 3-dehydrogenase [EC:1.1.1.62 1.1.1.270]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00100  Steroid biosynthesis
hsa00140  Steroid hormone biosynthesis
hsa01100  Metabolic pathways
hsa04913  Ovarian steroidogenesis
Module
hsa_M00101  Cholesterol biosynthesis, FPP => cholesterol
Network
nt06034  Cholesterol biosynthesis
  Element
N01624  Cholesterol biosynthesis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    51478 (HSD17B7)
   00140 Steroid hormone biosynthesis
    51478 (HSD17B7)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    51478 (HSD17B7)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.62  17beta-estradiol 17-dehydrogenase
     51478 (HSD17B7)
    1.1.1.270  3beta-hydroxysteroid 3-dehydrogenase
     51478 (HSD17B7)
SSDB
Motif
Pfam: adh_short adh_short_C2 KR Epimerase Sacchrp_dh_NADP NAD_binding_10 SDR GDP_Man_Dehyd Polysacc_synt_2 Eno-Rase_NADH_b TniB
Other DBs
NCBI-GeneID: 51478
NCBI-ProteinID: NP_057455
OMIM: 606756
HGNC: 5215
Ensembl: ENSG00000132196
UniProt: P56937
Position
1:162790702..162812823
AA seq 341 aa
MRKVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIV
QVDVSNLQSVFRASKELKQRFQRLDCIYLNAGIMPNPQLNIKALFFGLFSRKVIHMFSTA
EGLLTQGDKITADGLQEVFETNVFGHFILIRELEPLLCHSDNPSQLIWTSSRSARKSNFS
LEDFQHSKGKEPYSSSKYATDLLSVALNRNFNQQGLYSNVACPGTALTNLTYGILPPFIW
TLLMPAILLLRFFANAFTLTPYNGTEALVWLFHQKPESLNPLIKYLSATTGFGRNYIMTQ
KMDLDEDTAEKFYQKLLELEKHIRVTIQKTDNQARLSGSCL
NT seq 1026 nt   +upstreamnt  +downstreamnt
atgcgaaaggtggttttgatcaccggggctagcagtggcattggcctggccctctgcaag
cggctgctggcggaagatgatgagcttcatctgtgtttggcgtgcaggaacatgagcaag
gcagaagctgtctgtgctgctctgctggcctctcaccccactgctgaggtcaccattgtc
caggtggatgtcagcaacctgcagtcggtcttccgggcctccaaggaacttaagcaaagg
tttcagagattagactgtatatatctaaatgctgggatcatgcctaatccacaactaaat
atcaaagcacttttctttggcctcttttcaagaaaagtgattcatatgttctccacagct
gaaggcctgctgacccagggtgataagatcactgctgatggacttcaggaggtgtttgag
accaatgtctttggccattttatcctgattcgggaactggagcctctcctctgtcacagt
gacaatccatctcagctcatctggacatcatctcgcagtgcaaggaaatctaatttcagc
ctcgaggacttccagcacagcaaaggcaaggaaccctacagctcttccaaatatgccact
gaccttttgagtgtggctttgaacaggaacttcaaccagcagggtctctattccaatgtg
gcctgtccaggtacagcattgaccaatttgacatatggaattctgcctccgtttatatgg
acgctgttgatgccggcaatattgctacttcgcttttttgcaaatgcattcactttgaca
ccatataatggaacagaagctctggtatggcttttccaccaaaagcctgaatctctcaat
cctctgatcaaatatctgagtgccaccactggctttggaagaaattacattatgacccag
aagatggacctagatgaagacactgctgaaaaattttatcaaaagttactggaactggaa
aagcacattagggtcactattcaaaaaacagataatcaggccaggctcagtggctcatgc
ctataa

  All links  
Disease (1)   
   OMIM (1)   
Gene (17)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (7)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (29)   
   RefSeq(nuc) (5)   
   GenBank (12)   
   EMBL (12)   
Protein domain (11)   
   Pfam (11)   
All databases (63)   

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