KEGG   Homo sapiens (human): 5164Help
Entry
5164              CDS       T01001                                 

Gene name
PDK2, PDHK2, PDKII
Definition
(RefSeq) pyruvate dehydrogenase kinase 2
  KO
K00898  pyruvate dehydrogenase kinase 2/3/4 [EC:2.7.11.2]
Organism
hsa  Homo sapiens (human)
Drug target
Sodium dichloroacetate: D05857
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    5164 (PDK2)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.2  [pyruvate dehydrogenase (acetyl-transferring)] kinase
     5164 (PDK2)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: Other
  PDHK family [OT]
   5164 (PDK2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: BCDHK_Adom3 HATPase_c HATPase_c_3
Motif
Other DBs
NCBI-GeneID: 5164
NCBI-ProteinID: NP_002602
OMIM: 602525
HGNC: 8810
Ensembl: ENSG00000005882
Vega: OTTHUMG00000161948
Pharos: Q15119(Tbio)
UniProt: Q15119
Structure
PDB: 

Position
17q21.33
AA seq 407 aa AA seqDB search
MRWVWALLKNASLAGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLRQELPVR
LANIMKEINLLPDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIR
NRHNDVVPTMAQGVLEYKDTYGDDPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGST
NPAHPKHIGSIDPNCNVSEVVKDAYDMAKLLCDKYYMASPDLEIQEINAANSKQPIHMVY
VPSHLYHMLFELFKNAMRATVESHESSLILPPIKVMVALGEEDLSIKMSDRGGGVPLRKI
ERLFSYMYSTAPTPQPGTGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYL
KALSTDSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS
NT seq 1224 nt NT seq  +upstreamnt  +downstreamnt
atgcgctgggtgtgggcgctgctgaagaatgcgtccctggcaggggcgcccaagtacata
gagcacttcagcaagttctccccgtccccgctgtccatgaagcagtttctggacttcgga
tccagcaatgcctgtgagaaaacctccttcaccttcctcaggcaggagctgcctgtgcgc
ctggccaacatcatgaaagagatcaacctgcttcccgaccgagtgctgagcacaccctcc
gtgcagctggtgcagagctggtatgtccagagcctcctggacatcatggagttcctggac
aaggatcccgaggaccatcgcaccctgagccagttcactgacgccctggtcaccatccgg
aaccggcacaacgacgtggtgcccaccatggcacaaggcgtgcttgagtacaaggacacc
tacggcgatgaccccgtctccaaccagaacatccagtacttcctggaccgcttctacctc
agccgcatctccatccgcatgctcatcaaccagcacaccctcatctttgatggcagcacc
aacccagcccatcccaaacacatcggcagcatcgaccccaactgcaacgtctctgaggtg
gtcaaagatgcctacgacatggctaagctcctgtgtgacaagtattacatggcctcacct
gacctggagatccaggagatcaatgcagccaactccaaacagccgattcacatggtctac
gtcccctcccacctctaccacatgctctttgagctcttcaagaatgccatgagggcgact
gtggaaagccatgagtccagcctcattctcccacccatcaaggtcatggtggccttgggt
gaggaagatctgtccatcaagatgagtgaccgaggtgggggtgttcccttgaggaagatt
gagcgactcttcagctacatgtactccacagcacccaccccccagcctggcaccggggga
acgccgctggctggctttggttatgggctccccatttcccgcctctacgccaagtacttc
cagggagacctgcagctcttctccatggaaggctttgggaccgatgctgtcatctatctc
aaggccctgtccacggactcggtggagcgcctgcctgtctacaacaagtcagcctggcgc
cactaccagaccatccaggaggccggcgactggtgtgtgcccagcacggagcccaagaac
acgtccacgtaccgcgtcagctaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (1)   
   OMIM (1)   
Drug (1)   
   KEGG DRUG (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (9)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (6)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (4)   
DNA sequence (30)   
   RefSeq(nuc) (4)   
   GenBank (13)   
   EMBL (13)   
Protein domain (3)   
   Pfam (3)   
All databases (65)   

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