KEGG   Homo sapiens (human): 5222
Entry
5222              CDS       T01001                                 

Gene name
PGA5, Pg5
Definition
(RefSeq) pepsinogen A5
  KO
K06002  pepsin A [EC:3.4.23.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04974  Protein digestion and absorption
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    5222 (PGA5)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    5222 (PGA5)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.23  Aspartic endopeptidases
    3.4.23.1  pepsin A
     5222 (PGA5)
Peptidases and inhibitors [BR:hsa01002]
 Aspartic peptidases
  Family A1: pepsin family
   5222 (PGA5)
SSDB
Motif
Pfam: Asp TAXi_N A1_Propeptide Asp_protease_2
Other DBs
NCBI-GeneID: 5222
NCBI-ProteinID: NP_055039
OMIM: 169730
HGNC: 8887
Ensembl: ENSG00000256713
Vega: OTTHUMG00000168075
Pharos: P0DJD9(Tclin)
UniProt: P0DJD9
Position
11q12.2
AA seq 388 aa
MKWLLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAP
TLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNP
EDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFD
GILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDKSGSVVIFGGIDSSYYTGS
LNWVPVTVEGYWQITVDSITMNGETIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGAS
ENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSEGSCISGFQGMNVPTESGEL
WILGDVFIRQYFTVFDRANNQVGLAPVA
NT seq 1167 nt   +upstreamnt  +downstreamnt
atgaagtggctgctgctgctgggtctggtggcgctctctgagtgcatcatgtacaaggtc
cccctcatcagaaagaagtccttgaggcgcaccctgtccgagcgtggcctgctgaaggac
ttcctgaagaagcacaacctcaacccagccagaaagtacttcccccagtgggaggctccc
accctggtagatgaacagcccctggagaactacctggatatggagtacttcggcactatc
ggcatcggaactcctgcccaggatttcaccgtcgtctttgacaccggctcctccaacctg
tgggtgccctcagtctactgctccagtcttgcctgcaccaaccacaaccgcttcaaccct
gaggattcttccacctaccagtccaccagcgagacagtctccatcacctacggcaccggc
agcatgacaggcatcctcggatacgacactgtccaggttggaggcatctctgacaccaat
cagatcttcggcctgagcgagacggaacctggctccttcctgtattatgctcccttcgat
ggcatcctggggctggcctaccccagcatttcctcctccggggccacacccgtctttgac
aacatctggaaccagggcctggtttctcaggacctcttctctgtctacctcagcgccgat
gacaagagtggcagcgtggtgatctttggtggcattgactcttcttactacactggaagt
ctgaactgggtgcctgttaccgtcgagggttactggcagatcaccgtggacagcatcacc
atgaacggagagaccatcgcctgtgctgagggctgccaggccattgttgacaccggcacc
tctctgctgaccggcccaaccagccccattgccaacatccagagcgacatcggagccagc
gagaactcagatggcgacatggtggtcagctgctcagccatcagcagcctgcccgacatc
gtcttcaccatcaatggagtccagtaccccgtgccacccagtgcctacatcctgcagagc
gaggggagctgcatcagtggcttccagggcatgaacgtccccaccgaatctggagagctt
tggatcctgggtgatgtcttcatccgccagtactttaccgtcttcgacagggcaaacaac
caggtcggcctggcccctgtggcttaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (9)   
   RefSeq(nuc) (1)   
   GenBank (4)   
   EMBL (4)   
Protein domain (4)   
   Pfam (4)   
All databases (35)   

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KEGG   Homo sapiens (human): 643834
Entry
643834            CDS       T01001                                 

Gene name
PGA3
Definition
(RefSeq) pepsinogen A3
  KO
K06002  pepsin A [EC:3.4.23.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04974  Protein digestion and absorption
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    643834 (PGA3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    643834 (PGA3)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.23  Aspartic endopeptidases
    3.4.23.1  pepsin A
     643834 (PGA3)
Peptidases and inhibitors [BR:hsa01002]
 Aspartic peptidases
  Family A1: pepsin family
   643834 (PGA3)
SSDB
Motif
Pfam: Asp TAXi_N A1_Propeptide Asp_protease_2
Other DBs
NCBI-GeneID: 643834
NCBI-ProteinID: NP_001073275
OMIM: 169710
HGNC: 8885
Ensembl: ENSG00000229859
Vega: OTTHUMG00000168071
Pharos: P0DJD8(Tbio)
UniProt: P0DJD8
Structure
PDB: 
1QRP 1PSO 1PSN 1FLH 3UTL

Position
11q12.2
AA seq 388 aa
MKWLLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWKAP
TLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNP
EDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFD
GILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQSGSVVIFGGIDSSYYTGS
LNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGAS
ENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSEGSCISGFQGMNLPTESGEL
WILGDVFIRQYFTVFDRANNQVGLAPVA
NT seq 1167 nt   +upstreamnt  +downstreamnt
atgaagtggctgctgctgctgggtctggtggcactctctgagtgcatcatgtacaaggtc
cccctcatcagaaagaagtccttgaggcgcaccctgtccgagcgtggcctgctgaaggac
ttcctgaagaagcacaacctcaacccagccagaaagtacttcccccagtggaaggctccc
accctggtagatgaacagcccctggagaactacctggatatggagtacttcggcactatc
ggcatcggaactcctgcccaggatttcaccgtcgtctttgacaccggctcctccaacctg
tgggtgccctcagtctactgctccagtcttgcctgcaccaaccacaaccgcttcaaccct
gaggattcttccacctaccagtccaccagcgagacagtctccatcacctacggcaccggc
agcatgacaggcatcctcggatacgacactgtccaggttggaggcatctctgacaccaat
cagatcttcggcctgagcgagacggaacctggctccttcctgtattatgctcccttcgat
ggcatcctggggctggcctaccccagcatttcctcctccggggccacacccgtctttgac
aacatctggaaccagggcctggtttctcaggacctcttctctgtctacctcagcgccgat
gaccagagtggcagcgtggtgatctttggtggcattgactcttcttactacactggaagt
ctgaactgggtgcctgttaccgtcgagggttactggcagatcaccgtggacagcatcacc
atgaacggagaggccatcgcctgcgctgagggctgccaggccattgttgacaccggcacc
tctctgctgaccggcccaaccagccccattgccaacatccagagcgacatcggagccagc
gagaactcagatggcgacatggtggtcagctgctcagccatcagcagcctgcccgacatc
gtcttcaccatcaatggagtccagtaccccgtgccacccagtgcctacatcctgcagagc
gaggggagctgcatcagtggcttccagggcatgaacctccccaccgaatctggagagctt
tggatcctgggtgatgtcttcatccgccagtactttaccgtcttcgacagggcaaacaac
caggtcggcctggcccccgtggcttaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (13)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (21)   
   RefSeq(nuc) (1)   
   GenBank (10)   
   EMBL (10)   
Protein domain (4)   
   Pfam (4)   
All databases (48)   

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KEGG   Homo sapiens (human): 643847
Entry
643847            CDS       T01001                                 

Gene name
PGA4
Definition
(RefSeq) pepsinogen A4
  KO
K06002  pepsin A [EC:3.4.23.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04974  Protein digestion and absorption
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    643847 (PGA4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    643847 (PGA4)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.23  Aspartic endopeptidases
    3.4.23.1  pepsin A
     643847 (PGA4)
Peptidases and inhibitors [BR:hsa01002]
 Aspartic peptidases
  Family A1: pepsin family
   643847 (PGA4)
SSDB
Motif
Pfam: Asp TAXi_N A1_Propeptide Asp_protease_2
Other DBs
NCBI-GeneID: 643847
NCBI-ProteinID: NP_001073276
OMIM: 169720
HGNC: 8886
Ensembl: ENSG00000229183
Vega: OTTHUMG00000168073
Pharos: P0DJD7(Tbio)
UniProt: P0DJD7 A0A1S5UZ02 B7Z719
Structure
PDB: 
1QRP 1PSO 1PSN 1FLH 3UTL

Position
11q12.2
AA seq 388 aa
MKWLLLLGLVALSECIMYKVPLIRKKSLRRTLSERGLLKDFLKKHNLNPARKYFPQWEAP
TLVDEQPLENYLDMEYFGTIGIGTPAQDFTVVFDTGSSNLWVPSVYCSSLACTNHNRFNP
EDSSTYQSTSETVSITYGTGSMTGILGYDTVQVGGISDTNQIFGLSETEPGSFLYYAPFD
GILGLAYPSISSSGATPVFDNIWNQGLVSQDLFSVYLSADDQSGSVVIFGGIDSSYYTGS
LNWVPVTVEGYWQITVDSITMNGEAIACAEGCQAIVDTGTSLLTGPTSPIANIQSDIGAS
ENSDGDMVVSCSAISSLPDIVFTINGVQYPVPPSAYILQSEGSCISGFQGMNLPTESGEL
WILGDVFIRQYFTVFDRANNQVGLAPVA
NT seq 1167 nt   +upstreamnt  +downstreamnt
atgaagtggctgctgctgctgggtctggtggcgctctctgagtgcatcatgtacaaggtc
cccctcatcagaaagaagtccttgaggcgcaccctgtccgagcgtggcctgctgaaggac
ttcctgaagaagcacaacctcaacccagccagaaagtacttcccccagtgggaggctccc
accctggtagatgaacagcccctggagaactacctggatatggagtacttcggcactatc
ggcatcggaactcctgcccaggatttcaccgtcgtctttgacaccggctcctccaacctg
tgggtgccctcagtctactgctccagtcttgcctgcaccaaccacaaccgcttcaaccct
gaggattcttccacctaccagtccaccagcgagacagtctccatcacctacggcaccggc
agcatgacaggcatcctcggatacgacactgtccaggttggaggcatctctgacaccaat
cagatcttcggcctgagcgagacggaacctggctccttcctgtattatgctcccttcgat
ggcatcctggggctggcctaccccagcatttcctcctccggggccacacccgtctttgac
aacatctggaaccagggcctggtttctcaggacctcttctctgtctacctcagcgccgat
gaccagagtggcagcgtggtgatctttggtggcattgactcttcttactacactggaagt
ctgaactgggtgcctgttaccgtcgagggttactggcagatcaccgtggacagcatcacc
atgaacggagaggccatcgcctgcgctgagggctgccaggccattgttgacaccggcacc
tctctgctgaccggcccaaccagccccattgccaacatccagagcgacatcggagccagc
gagaactcagatggcgacatggtggtcagctgctcagccatcagcagcctgcccgacatc
gtcttcaccatcaatggagtccagtaccccgtgccacccagtgcctacatcctgcagagc
gaggggagctgcatcagtggcttccagggcatgaacctccccaccgaatctggagagctt
tggatcctgggtgatgtcttcatccgccagtactttaccgtcttcgacagggcaaacaac
caggtcggcctggcccccgtggcttaa

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (4)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (5)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (17)   
   RefSeq(nuc) (1)   
   GenBank (8)   
   EMBL (8)   
Protein domain (4)   
   Pfam (4)   
All databases (45)   

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