KEGG   Homo sapiens (human): 5287Help
Entry
5287              CDS       T01001                                 

Gene name
PIK3C2B, C2-PI3K
Definition
(RefSeq) phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
  KO
K00923  phosphatidylinositol-4-phosphate 3-kinase [EC:2.7.1.154]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00562  Inositol phosphate metabolism
hsa01100  Metabolic pathways
hsa04070  Phosphatidylinositol signaling system
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    5287 (PIK3C2B)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    5287 (PIK3C2B)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.154  phosphatidylinositol-4-phosphate 3-kinase
     5287 (PIK3C2B)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: PI3_PI4_kinase PI3Ka PI3K_C2 PI3K_rbd PX C2 DUF4135 HEAT_2
Motif
Other DBs
NCBI-GeneID: 5287
NCBI-ProteinID: NP_002637
OMIM: 602838
HGNC: 8972
Ensembl: ENSG00000133056
Vega: OTTHUMG00000036101
Pharos: O00750(Tchem)
UniProt: O00750 A2RUF7 Q4LE65
Position
1q32.1
AA seq 1634 aa AA seqDB search
MSSTQGNGEHWKSLESVGISRKELAMAEALQMEYDALSRLRHDKEENRAKQNADPSLISW
DEPGVDFYSKPAGRRTDLKLLRGLSGSDPTLNYNSLSPQEGPPNHSTSQGPQPGSDPWPK
GSLSGDYLYIFDGSDGGVSSSPGPGDIEGSCKKLSPPPLPPRASIWDTPPLPPRKGSPSS
SKISQPSDINTFSLVEQLPGKLLEHRILEEEEVLGGGGQGRLLGSVDYDGINDAITRLNL
KSTYDAEMLRDATRGWKEGRGPLDFSKDTSGKPVARSKTMPPQVPPRTYASRYGNRKNAT
PGKNRRISAAPVGSRPHTVANGHELFEVSEERDEEVAAFCHMLDILRSGSDIQDYFLTGY
VWSAVTPSPEHLGDEVNLKVTVLCDRLQEALTFTCNCSSTVDLLIYQTLCYTHDDLRNVD
VGDFVLKPCGLEEFLQNKHALGSHEYIQYCRKFDIDIRLQLMEQKVVRSDLARTVNDDQS
PSTLNYLVHLQERPVKQTISRQALSLLFDTYHNEVDAFLLADGDFPLKADRVVQSVKAIC
NALAAVETPEITSALNQLPPCPSRMQPKIQKDPSVLAVRENREKVVEALTAAILDLVELY
CNTFNADFQTAVPGSRKHDLVQEACHFARSLAFTVYATHRIPIIWATSYEDFYLSCSLSH
GGKELCSPLQTRRAHFSKYLFHLIVWDQQICFPVQVNRLPRETLLCATLYALPIPPPGSS
SEANKQRRVPEALGWVTTPLFNFRQVLTCGRKLLGLWPATQENPSARWSAPNFHQPDSVI
LQIDFPTSAFDIKFTSPPGDKFSPRYEFGSLREEDQRKLKDIMQKESLYWLTDADKKRLW
EKRYYCHSEVSSLPLVLASAPSWEWACLPDIYVLLKQWTHMNHQDALGLLHATFPDQEVR
RMAVQWIGSLSDAELLDYLPQLVQALKYECYLDSPLVRFLLKRAVSDLRVTHYFFWLLKD
GLKDSQFSIRYQYLLAALLCCCGKGLREEFNRQCWLVNALAKLAQQVREAAPSARQGILR
TGLEEVKQFFALNGSCRLPLSPSLLVKGIVPRDCSYFNSNAVPLKLSFQNVDPLGENIRV
IFKCGDDLRQDMLTLQMIRIMSKIWVQEGLDMRMVIFRCFSTGRGRGMVEMIPNAETLRK
IQVEHGVTGSFKDRPLADWLQKHNPGEDEYEKAVENFIYSCAGCCVATYVLGICDRHNDN
IMLKTTGHMFHIDFGRFLGHAQMFGNIKRDRAPFVFTSDMAYVINGGDKPSSRFHDFVDL
CCQAYNLIRKHTHLFLNLLGLMLSCGIPELSDLEDLKYVYDALRPQDTEANATTYFTRLI
ESSLGSVATKLNFFIHNLAQMKFTGSDDRLTLSFASRTHTLKSSGRISDVFLCRHEKIFH
PNKGYIYVVKVMRENTHEATYIQRTFEEFQELHNKLRLLFPSSHLPSFPSRFVIGRSRGE
AVAERRREELNGYIWHLIHAPPEVAECDLVYTFFHPLPRDEKAMGTSPAPKSSDGTWARP
VGKVGGEVKLSISYKNNKLFIMVMHIRGLQLLQDGNDPDPYVKIYLLPDPQKTTKRKTKV
ARKTCNPTYNEMLVYDGIPKGDLQQRELQLSVLSEQGFWENVLLGEVNIRLRELDLAQEK
TGWFALGSRSHGTL
NT seq 4905 nt NT seq  +upstreamnt  +downstreamnt
atgtcttcgactcagggcaatggggaacactggaagtccctggagtcagtgggcatcagc
cgcaaagagctagcgatggccgaagccctgcagatggagtatgatgccctgtcccggctc
cggcatgacaaggaggagaacagagccaagcagaacgcagacccctctctcatcagctgg
gatgagcctggggtagacttttacagcaagccagcaggaaggcggaccgacctcaagctg
ttacgcggtctctctggctctgatcctacccttaactacaactcactctccccacaggaa
gggccgcccaaccactctacctcccaagggccacagcctggctcagatccctggcccaaa
ggctccctgtctggagactatctctacatttttgatggttcagatgggggagtctcttcg
tccccaggaccaggggacatagagggctcttgcaagaaactatccccacctcctctgcct
ccccgagcttctatctgggatacccctcccctgcctcccagaaaggggtccccctcatcc
tccaagatctcccagcccagtgacatcaacactttctctttggtcgaacaattgccgggc
aaactgctagagcatcggatcctagaagaggaagaggtgctgggaggtgggggtcagggg
cgcctactggggtctgtggactatgatggtatcaatgatgcaattactaggctcaacttg
aaatcgacctatgatgcggagatgttgcgggatgccaccaggggctggaaggagggccga
gggccgctggacttcagcaaagacacctctggaaaacccgtggccaggagcaagactatg
ccccctcaggtgcccccccgcacctatgcctcccgctatggcaaccgaaagaatgcgacg
cctggcaagaaccgccggatttctgcagccccggtgggctcccggccccacactgttgcc
aatggccatgagttgtttgaggtctcagaagagagagatgaggaggttgctgcattttgc
cacatgctggatatccttcgatctggctctgacatccaagactacttcctcactggctat
gtctggagtgctgtcacccctagcccagagcacctcggggatgaggtcaacctgaaggtg
actgtgttgtgtgacaggcttcaagaggcactcactttcacctgcaactgttcctccact
gtagacttgcttatctaccagaccctgtgctacacccatgatgacctgaggaatgtggac
gtgggtgactttgtgctaaagccctgcgggctggaggagttcctgcagaacaagcatgcc
ttgggcagtcatgagtacatccaatactgccgcaagtttgacattgacattcggctacag
ctgatggagcagaaggttgtgcgcagtgacctggcccggacggtgaatgatgaccagagc
ccctccaccttgaactacctcgtccatctccaagagaggcctgtcaagcagaccatcagc
aggcaggccctgagtcttctgttcgacacttaccacaatgaggtggatgccttcctgctg
gctgatggagacttcccactgaaggctgacagggtggtccagtccgtcaaggccatctgc
aacgccctggccgccgtggaaacccctgagatcaccagtgctctcaaccagctgcccccc
tgcccctcccgcatgcagcctaaaattcagaaggatcccagtgtcttggctgtgagggaa
aaccgagagaaggtcgtggaagccctgaccgctgccatcttggacctggtggagctgtac
tgcaacacattcaacgcagacttccagacggcagtgcccgggagccgcaagcatgacctg
gtccaggaggcctgccatttcgccaggtccctggccttcactgtctatgccacccaccgc
atccccatcatctgggctaccagctatgaagatttctacctctcctgctccctcagccat
ggcggcaaggagctgtgcagccccctgcagacccgaagagctcacttctccaagtacctc
ttccacctcatcgtctgggaccagcagatctgcttcccagtgcaggtgaaccggctgcct
cgggagacactgctgtgtgccactctctatgctctgcccatccccccaccggggagctcc
tcagaggccaataagcagcggcgggtgcctgaagccctgggctgggtcactaccccactc
ttcaacttcaggcaggtcctgacctgtggccggaagcttctgggtttgtggccagcaaca
caggaaaatcccagcgcccgttggagtgcacctaatttccaccagccagacagtgtcatc
ctgcagattgacttccccacctcggcctttgacatcaagttcaccagcccccctggagac
aagttcagcccccgctatgagtttggcagcctccgggaagaagaccagcgcaagcttaaa
gacatcatgcagaaagagtccttgtactggctcactgatgctgacaagaagcgcctgtgg
gagaagcgatattactgccactcggaggtgagctcgctccccctggtgctcgccagcgcc
cccagctgggagtgggcttgcctgcctgacatctatgttctcctgaagcagtggacccac
atgaaccaccaggatgccctggggctcctgcatgccaccttcccggaccaggaggtgcgt
cgtatggctgtgcagtggattggctcactctcagatgctgagctgctagactacctgccc
cagctggtacaggccctgaagtatgaatgctacctggacagcccgttggtgcgcttcctc
ctgaaacgagctgtgtctgacttgagagtgactcactacttcttctggttactgaaggac
ggcctcaaggactctcagttcagcatccgctaccagtatctgctggcagccttactgtgc
tgctgtggcaaggggctgagagaagagtttaaccgccagtgctggcttgtcaatgccctg
gccaaactggcccagcaggtccgggaggcagccccatctgcaaggcagggaatcctccgc
acgggcctggaggaggtgaagcagttctttgccctcaatggctcgtgccgcttgccactc
agccccagtctgctggttaagggaattgtgcccagggactgttcctacttcaactccaat
gctgtccccctcaaactctccttccaaaatgtggatcccctgggtgagaacatccgtgtc
atcttcaagtgtggggacgaccttcgccaggacatgctaacgctgcagatgattcgcatc
atgagcaagatctgggtccaggaggggctggacatgcgcatggtcatcttccgctgcttc
tccaccggccggggcagagggatggtggagatgatccctaatgctgagaccctgcgtaag
atccaggtggagcatggggtgaccggctcgttcaaggaccggcccctggcagactggctg
cagaaacacaaccctggggaggacgagtatgagaaggctgtggagaactttatctactcc
tgcgctggctgctgcgtggccacgtacgtcttgggcatctgtgaccgacataatgacaac
atcatgctgaagaccactggtcacatgttccacattgattttggccgcttcctgggccat
gcccagatgtttggcaacatcaagcgggaccgtgccccctttgtcttcacctcggacatg
gcgtatgtcatcaacgggggtgacaagccttccagccgcttccatgattttgttgacctt
tgctgccaagcctacaacctcattcgcaagcacacccacctcttcctcaaccttctgggc
ctgatgttgtcctgtgggatccctgaactctcagacctggaggacctcaagtatgtgtac
gatgccctgaggcctcaggatacagaggccaatgccactacctacttcactaggttgatt
gagtccagcctgggcagtgtagccacaaagctcaattttttcatccataatctggctcag
atgaagttcacgggctcagatgaccggctgaccctctcctttgcctcccgaacacacact
ctcaagagctctggccgaatcagtgatgttttcctctgccgccatgagaagatcttccac
cccaacaaaggctatatatatgtggtaaaggtgatgcgagagaacactcacgaggccacc
tacatccagcggacctttgaggagttccaggaattacacaataagttgcggctgctcttc
ccttcttcccacttgcccagcttccctagtcgcttcgtgatcggccgctcccggggagag
gcggtggccgagcggcggagggaggagctaaacggttacatctggcacttgatccacgca
ccccctgaggtggccgagtgtgatttggtgtacaccttcttccacccactgccccgggat
gagaaggctatgggcaccagcccagctcctaagtcctcagatggcacatgggcccggccc
gtcggaaaggtgggaggggaggtgaagctgtccatctcctacaaaaacaataaactcttc
atcatggtgatgcatattcggggcttgcaactgctccaggatggaaatgaccctgacccc
tatgtgaaaatttacctccttcctgaccctcagaaaaccactaagaggaaaaccaaagtg
gcccggaaaacctgcaatcctacctacaatgagatgttggtatatgatgggatccccaag
ggtgacctgcagcagcgggagctccagctgagcgtgctgagtgagcagggattctgggag
aacgtcctcctcggtgaggtgaacatccgcctgcgagagctggacctggctcaggagaag
accggctggttcgccctgggatctcgaagtcatggcaccttgtga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Disease (1)   
   OMIM (1)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   UniGene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
   PHAROS (1)   
   VEGA (1)   
Protein sequence (13)   
   UniProt (3)   
   SWISS-PROT (1)   
   RefSeq(pep) (9)   
DNA sequence (31)   
   RefSeq(nuc) (11)   
   GenBank (10)   
   EMBL (10)   
Protein domain (8)   
   Pfam (8)   
All databases (86)   

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