| Entry |
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| Symbol |
PIM1, PIM
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| Name |
(RefSeq) Pim-1 proto-oncogene, serine/threonine kinase
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| KO |
| K04702 | proto-oncogene serine/threonine-protein kinase Pim-1 [EC:2.7.11.1] |
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| Organism |
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| Pathway |
| hsa04933 | AGE-RAGE signaling pathway in diabetic complications |
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| Network |
nt06160 Human T-cell leukemia virus 1 (HTLV-1) nt06162 Hepatitis B virus (HBV) nt06164 Kaposi sarcoma-associated herpesvirus (KSHV) nt06165 Epstein-Barr virus (EBV) nt06219 JAK-STAT signaling (cancer) nt06263 Hepatocellular carcinoma nt06266 Non-small cell lung cancer nt06275 Acute myeloid leukemia nt06276 Chronic myeloid leukemia |
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| Element |
| N00053 | Cytokine-Jak-STAT signaling pathway |
| N00054 | Duplication or mutation-activated FLT3 to Jak-STAT signaling pathway |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
5292 (PIM1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
5292 (PIM1)
05206 MicroRNAs in cancer
5292 (PIM1)
09162 Cancer: specific types
05221 Acute myeloid leukemia
5292 (PIM1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
5292 (PIM1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:hsa01001]
5292 (PIM1)
Enzymes [BR:hsa01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
5292 (PIM1)
Protein kinases [BR:hsa01001]
Serine/threonine kinases: CAMK group
PIM family [OT]
5292 (PIM1)
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| SSDB |
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| Motif |
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| Other DBs |
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| Structure |
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| Position |
6:37170152..37175428
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| AA seq |
313 aa
MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
ELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
PFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETA
EIHLHSLSPGPSK |
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| NT seq |
942 nt +upstreamnt +downstreamnt
atgctcttgtccaaaatcaactcgcttgcccacctgcgcgccgcgccctgcaacgacctg
cacgccaccaagctggcgcccggcaaggagaaggagcccctggagtcgcagtaccaggtg
ggcccgctactgggcagcggcggcttcggctcggtctactcaggcatccgcgtctccgac
aacttgccggtggccatcaaacacgtggagaaggaccggatttccgactggggagagctg
cctaatggcactcgagtgcccatggaagtggtcctgctgaagaaggtgagctcgggtttc
tccggcgtcattaggctcctggactggttcgagaggcccgacagtttcgtcctgatcctg
gagaggcccgagccggtgcaagatctcttcgacttcatcacggaaaggggagccctgcaa
gaggagctggcccgcagcttcttctggcaggtgctggaggccgtgcggcactgccacaac
tgcggggtgctccaccgcgacatcaaggacgaaaacatccttatcgacctcaatcgcggc
gagctcaagctcatcgacttcgggtcgggggcgctgctcaaggacaccgtctacacggac
ttcgatgggacccgagtgtatagccctccagagtggatccgctaccatcgctaccatggc
aggtcggcggcagtctggtccctggggatcctgctgtatgatatggtgtgtggagatatt
cctttcgagcatgacgaagagatcatcaggggccaggttttcttcaggcagagggtctct
tcagaatgtcagcatctcattagatggtgcttggccctgagaccatcagataggccaacc
ttcgaagaaatccagaaccatccatggatgcaagatgttctcctgccccaggaaactgct
gagatccacctccacagcctgtcgccggggcccagcaaatag |
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