KEGG   Homo sapiens (human): 5356
Entry
5356              CDS       T01001                                 
Symbol
PLRG1, Cwc1, PRL1, PRP46, PRPF46, TANGO4
Name
(RefSeq) pleiotropic regulator 1
  KO
K12862  pleiotropic regulator 1
Organism
hsa  Homo sapiens (human)
Pathway
hsa03040  Spliceosome
Network
nt06547  Spliceosome
  Element
N01971  spliceosome activation
N01972  Spliceosome catalysis (branching)
N01993  Spliceosome catalysis (exon ligation)
N01994  Spliceosome disassembly
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    5356 (PLRG1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:hsa03041]
    5356 (PLRG1)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5356 (PLRG1)
Spliceosome [BR:hsa03041]
 Complex B
  Other components
   Prp19 complex
    5356 (PLRG1)
 Complex C
   Prp19-CDC5 complex
    5356 (PLRG1)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  Other factors with a suspected DNA repair function
   PSO4 complex
    5356 (PLRG1)
SSDB
Motif
Pfam: Beta-prop_WDR5 Beta-prop_WDR3_1st WD40 Beta-prop_THOC3 WD40_Prp19 Beta-prop_WDR3_2nd WD40_WDHD1_1st WD40_Gbeta WD40_CDC20-Fz Beta-prop_WDR36-Utp21_2nd EIF3I Beta-prop_EML_2 WDR55 Beta-prop_TEP1_2nd Beta-prop_CAF1B_HIR1 Beta-prop_WDR90_POC16_2nd Beta-prop_WDR36-Utp21_1st Beta-prop_WDR41 Beta-prop_WDR75_1st WD40_MABP1-WDR62_2nd Beta-prop_TEP1_C Beta-prop_EML Beta-prop_SCAP NBCH_WD40 Beta-prop_SPT8 Beta-prop_EIPR1 Beta-prop_DCAF4 WD40_RFWD3 WD40_MABP1-WDR62_1st Beta-prop_NWD2_C WDR90_beta-prop_4th Beta-prop_IFT122_1st Beta-prop_IFT140_1st Beta-prop_Aladin ANAPC4_WD40 Beta-prop_ACSF4 Beta-prop_DCAF12 Nucleoporin_N WDR54 KNTC1_N Beta-prop_WDR11_2nd VPS8_N Beta-prop_WDR19_1st
Other DBs
NCBI-GeneID: 5356
NCBI-ProteinID: NP_002660
OMIM: 605961
HGNC: 9089
Ensembl: ENSG00000171566
UniProt: O43660
Structure
Position
4:complement(154535005..154550400)
AA seq 514 aa
MVEEVQKHSVHTLVFRSLKRTHDMFVADNGKPVPLDEESHKRKMAIKLRNEYGPVLHMPT
SKENLKEKGPQNATDSYVHKQYPANQGQEVEYFVAGTHPYPPGPGVALTADTKIQRMPSE
SAAQSLAVALPLQTKADANRTAPSGSEYRHPGASDRPQPTAMNSIVMETGNTKNSALMAK
KAPTMPKPQWHPPWKLYRVISGHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKL
SLTGHISTVRGVIVSTRSPYLFSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYGLDLHPTI
DVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVATVRCQAAEPQIITGSHDTTIRLWDLV
AGKTRVTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLT
VNSDGVLVSGADNGTMHLWDWRTGYNFQRVHAAVQPGSLDSESGIFACAFDQSESRLLTA
EADKTIKVYREDDTATEETHPVSWKPEIIKRKRF
NT seq 1545 nt   +upstreamnt  +downstreamnt
atggtcgaggaggtacagaaacattctgtacacacccttgtgttcaggtcgttgaagagg
acccatgacatgtttgtagctgataatggaaaacctgtgcctttagatgaagagagtcac
aaacgaaaaatggcaatcaagcttcgtaatgagtatggtcctgtgttgcatatgcctact
tcaaaagaaaatcttaaagagaagggtcctcagaatgcaacggattcatatgttcataaa
cagtaccctgccaatcaaggacaagaagttgaatactttgtggcaggtacacatccatac
ccaccaggacctggggttgctttgacagcagatactaagatccagagaatgccaagtgaa
tcagctgcacagtccttagcggtggcattacctttgcagaccaaggctgatgcaaatcgt
actgcccctagtggaagtgaataccgacatcctggggcttctgaccgtccacagcctaca
gcgatgaattcaattgtcatggagactggcaataccaagaactctgcactgatggctaaa
aaagcccctacaatgccaaaaccccagtggcacccaccgtggaaactctacagggttatc
agtgggcatcttggctgggttcgatgtattgctgtggaacctggaaatcagtggtttgtt
actggatctgctgacagaactataaagatctgggacttggctagtggcaaattaaaactg
tcattgactgggcatattagtactgtgcggggcgtgatagtaagcacaaggagcccatat
ctgttctcttgtggagaagacaaacaagtgaaatgctgggatctcgaatacaataaggtt
atacggcattatcatggacatttaagtgcagtgtatggtttggatttgcacccgacaatc
gatgtgttggtaacctgtagtcgagattcaactgcacggatttgggatgtgagaactaaa
gccagtgtacacacattatctggacatacaaatgcagttgctacagtgagatgtcaggct
gcagaaccacaaattattacaggaagccatgatactacaattcgattatgggatctggtg
gctggaaaaacaagagtgacattaacaaatcacaaaaaatcagttagggctgtggtttta
catccaagacattacacatttgcatctggttctccagataacataaagcagtggaaattc
cctgatggaagtttcattcaaaatctttccggtcataatgctattattaacacattgacg
gtaaattctgatggagtgcttgtatctggagctgacaatggcaccatgcatctttgggac
tggagaactggctacaattttcagagagttcacgcagctgtgcaacctgggtctttggac
agtgaatcaggaatatttgcttgtgcttttgatcagtctgaaagtcgattactaacagct
gaagctgataaaaccattaaagtatacagagaggatgacacagccacagaagaaactcat
ccagtcagctggaaaccagaaattatcaagagaaagagattttaa

  All links  
Disease (1)   
   OMIM (1)   
Gene (11)   
   RefGene (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (20)   
   RefSeq(nuc) (2)   
   GenBank (9)   
   EMBL (9)   
3D Structure (35)   
   PDB (35)   
Protein domain (43)   
   Pfam (43)   
All databases (114)   

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