KEGG   Homo sapiens (human): 53616
Entry
53616             CDS       T01001                                 
Symbol
ADAM22, ADAM 22, DEE61, EIEE61, MDC2
Name
(RefSeq) disintegrin and metalloproteinase domain-containing protein 22 isoform 1 preproprotein
  KO
K16068  disintegrin and metalloproteinase domain-containing protein 22 [EC:3.4.24.-]
Organism
hsa  Homo sapiens (human)
Disease
H00606  Early infantile epileptic encephalopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:hsa01002]
    53616 (ADAM22)
Peptidases and inhibitors [BR:hsa01002]
 Metallo peptidases
  Family M12: astacin/adamalysin family
   53616 (ADAM22)
SSDB
Motif
Pfam: Reprolysin ADAM_CR Disintegrin Pep_M12B_propep Reprolysin_3 EGF_2 Reprolysin_4 Reprolysin_2 EGF_Teneurin ADAMTS_CR_2
Other DBs
NCBI-GeneID: 53616
NCBI-ProteinID: NP_068369
OMIM: 603709
HGNC: 201
UniProt: Q9P0K1
Structure
Position
7:87934251..88202889
AA seq 906 aa
MQAAVAVSVPFLLLCVLGTCPPARCGQAGDASLMELEKRKENRFVERQSIVPLRLIYRSG
GEDESRHDALDTRVRGDLGGPQLTHVDQASFQVDAFGTSFILDVVLNHDLLSSEYIERHI
EHGGKTVEVKGGEHCYYQGHIRGNPDSFVALSTCHGLHGMFYDGNHTYLIEPEENDTTQE
DFHFHSVYKSRLFEFSLDDLPSEFQQVNITPSKFILKPRPKRSKRQLRRYPRNVEEETKY
IELMIVNDHLMFKKHRLSVVHTNTYAKSVVNMADLIYKDQLKTRIVLVAMETWATDNKFA
ISENPLITLREFMKYRRDFIKEKSDAVHLFSGSQFESSRSGAAYIGGICSLLKGGGVNEF
GKTDLMAVTLAQSLAHNIGIISDKRKLASGECKCEDTWSGCIMGDTGYYLPKKFTQCNIE
EYHDFLNSGGGACLFNKPSKLLDPPECGNGFIETGEECDCGTPAECVLEGAECCKKCTLT
QDSQCSDGLCCKKCKFQPMGTVCREAVNDCDIRETCSGNSSQCAPNIHKMDGYSCDGVQG
ICFGGRCKTRDRQCKYIWGQKVTASDKYCYEKLNIEGTEKGNCGKDKDTWIQCNKRDVLC
GYLLCTNIGNIPRLGELDGEITSTLVVQQGRTLNCSGGHVKLEEDVDLGYVEDGTPCGPQ
MMCLEHRCLPVASFNFSTCLSSKEGTICSGNGVCSNELKCVCNRHWIGSDCNTYFPHNDD
AKTGITLSGNGVAGTNIIIGIIAGTILVLALILGITAWGYKNYREQRQLPQGDYVKKPGD
GDSFYSDIPPGVSTNSASSSKKRSNGLSHSWSERIPDTKHISDICENGRPRSNSWQGNLG
GNKKKIRGKRFRPRSNSTETLSPAKSPSSSTGSIASSRKYPYPMPPLPDEDKKVNRQSAR
LWETSI
NT seq 2721 nt   +upstreamnt  +downstreamnt
atgcaggcggcagtggctgtgtccgtgcccttcttgctgctctgtgtcctggggacctgc
cctccggcgcgctgcggccaggcaggagacgcctcattgatggagctagagaagaggaag
gaaaaccgcttcgtggagcgccagagcatcgtgccactgcgcctcatctaccgctcgggc
ggcgaagacgaaagtcggcacgacgcgctcgacacgcgggtgcggggcgacctcggtggc
ccgcagttgactcatgttgaccaagcaagcttccaggttgatgcctttggaacgtcattc
attctcgatgtcgtgctaaatcatgatttgctgtcctctgaatacatagagagacacatt
gaacatggaggcaagactgtggaagttaaaggaggagagcactgttactaccagggccat
atccgaggaaaccctgactcatttgttgcattgtcaacatgccacggacttcatgggatg
ttctatgacgggaaccacacatatctcattgagccagaagaaaatgacactactcaagag
gatttccattttcattcagtttacaaatccagactgtttgaattttccttggatgatctt
ccatctgaatttcagcaagtaaacattactccatcaaaatttattttgaagccaagacca
aaaaggagtaaacggcagcttcgtcgatatcctcgtaatgtagaagaagaaaccaaatac
attgaactgatgattgtgaatgatcaccttatgtttaaaaaacatcggctttccgttgta
cataccaatacctatgcgaaatctgtggtgaacatggcagatttaatatataaagaccaa
cttaagaccaggatagtattggttgctatggaaacctgggcgactgacaacaagtttgcc
atatctgaaaatccattgatcaccctacgtgagtttatgaaatacaggagggattttatc
aaagagaaaagtgatgcagttcaccttttttcgggaagtcaatttgagagtagccggagc
ggggcagcttatattggtgggatttgctcgttgctgaaaggaggaggcgtgaatgaattt
gggaaaactgatttaatggctgttacacttgcccagtcattagcccataatattggtatt
atctcagacaaaagaaagttagcaagtggtgaatgtaaatgcgaggacacgtggtccggg
tgcataatgggagacactggctattatcttcctaaaaagttcacccagtgtaatattgaa
gagtatcatgacttcctgaatagtggaggtggtgcctgccttttcaacaaaccttctaag
cttcttgatcctcctgagtgtggcaatggcttcattgaaactggagaggagtgtgattgt
ggaaccccggccgaatgtgtccttgaaggagcagagtgttgtaagaaatgcaccttgact
caagactctcaatgcagtgacggtctttgctgtaaaaagtgcaagtttcagcctatgggc
actgtgtgccgagaagcagtaaatgattgtgatattcgtgaaacgtgctcaggaaattca
agccagtgtgcccctaatattcataaaatggatggatattcatgtgatggtgttcaggga
atttgctttggaggaagatgcaaaaccagagatagacaatgcaaatacatttgggggcaa
aaggtgacagcatcagacaaatattgctatgagaaactgaatattgaagggacggagaag
ggtaactgtgggaaagacaaagacacatggatacagtgcaacaaacgggatgtgctttgt
ggttaccttttgtgtaccaatattggcaatatcccaaggcttggagaactcgatggtgaa
atcacatctactttagttgtgcagcaaggaagaacattaaactgcagtggtgggcatgtt
aagcttgaagaagatgtagatcttggctatgtggaagatgggacaccttgtggtccccaa
atgatgtgcttagaacacaggtgtcttcctgtggcttctttcaactttagtacttgcttg
agcagtaaagaaggcactatttgctcaggaaatggagtttgcagtaatgagctgaagtgt
gtgtgtaacagacactggataggttctgattgcaacacttacttccctcacaatgatgat
gcaaagactggtatcactctgtctggcaatggtgttgctggcaccaatatcataataggc
ataattgctggcaccattttagtgctggccctcatattaggaataactgcgtggggttat
aaaaactatcgagaacagagacagttaccccagggagattatgtaaaaaagcctggagat
ggtgactctttttatagcgacattcctcccggagtcagcacaaactcagcatctagttct
aagaagaggtcaaatgggctctctcattcttggagtgaaaggattccagacacaaaacat
atttcagacatctgtgaaaatgggcgacctcgaagtaactcttggcaaggtaacctggga
ggcaacaaaaagaaaatcagaggcaaaagatttagacctcggtctaattcaactgagact
ttatctcctgccaagtctccttcttcatcaactgggtctattgcctccagcagaaaatac
ccttacccaatgcctccacttcctgatgaggacaagaaagtgaaccgacaaagtgccagg
ctatgggagacatccatttaa

  All links  
Disease (2)   
   OMIM (2)   
Gene (13)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (48)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (46)   
DNA sequence (78)   
   RefSeq(nuc) (46)   
   GenBank (16)   
   EMBL (16)   
3D Structure (10)   
   PDB (10)   
Protein domain (10)   
   Pfam (10)   
All databases (161)   

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