KEGG   Homo sapiens (human): 54209
Entry
54209             CDS       T01001                                 
Symbol
TREM2, AD17, PLOSL2, TREM-2, Trem2a, Trem2b, Trem2c
Name
(RefSeq) triggering receptor expressed on myeloid cells 2
  KO
K14378  triggering receptor expressed on myeloid cells 2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04380  Osteoclast differentiation
Disease
H00056  Alzheimer disease
H00438  Nasu-Hakola disease
Drug target
Iluzanebart: D12996
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04380 Osteoclast differentiation
    54209 (TREM2)
SSDB
Motif
Pfam: V-set ig Ig_3
Other DBs
NCBI-GeneID: 54209
NCBI-ProteinID: NP_061838
OMIM: 605086
HGNC: 17761
Ensembl: ENSG00000095970
UniProt: Q9NZC2 Q5TCX1
Structure
Position
6:complement(41158508..41163116)
AA seq 230 aa
MEPLRLLILLFVTELSGAHNTTVFQGVAGQSLQVSCPYDSMKHWGRRKAWCRQLGEKGPC
QRVVSTHNLWLLSFLRRWNGSTAITDDTLGGTLTITLRNLQPHDAGLYQCQSLHGSEADT
LRKVLVEVLADPLDHRDAGDLWFPGESESFEDAHVEHSISRSLLEGEIPFPPTSILLLLA
CIFLIKILAASALWAAAWHGQKPGTHPPSELDCGHDPGYQLQTLPGLRDT
NT seq 693 nt   +upstreamnt  +downstreamnt
atggagcctctccggctgctcatcttactctttgtcacagagctgtccggagcccacaac
accacagtgttccagggcgtggcgggccagtccctgcaggtgtcttgcccctatgactcc
atgaagcactgggggaggcgcaaggcctggtgccgccagctgggagagaagggcccatgc
cagcgtgtggtcagcacgcacaacttgtggctgctgtccttcctgaggaggtggaatggg
agcacagccatcacagacgataccctgggtggcactctcaccattacgctgcggaatcta
caaccccatgatgcgggtctctaccagtgccagagcctccatggcagtgaggctgacacc
ctcaggaaggtcctggtggaggtgctggcagaccccctggatcaccgggatgctggagat
ctctggttccccggggagtctgagagcttcgaggatgcccatgtggagcacagcatctcc
aggagcctcttggaaggagaaatccccttcccacccacttccatccttctcctcctggcc
tgcatctttctcatcaagattctagcagccagcgccctctgggctgcagcctggcatgga
cagaagccagggacacatccacccagtgaactggactgtggccatgacccagggtatcag
ctccaaactctgccagggctgagagacacgtga

  All links  
Disease (4)   
   OMIM (4)   
Gene (12)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (5)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (12)   
   RefSeq(nuc) (2)   
   GenBank (5)   
   EMBL (5)   
3D Structure (14)   
   PDB (14)   
Protein domain (3)   
   Pfam (3)   
All databases (50)   

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