KEGG   Homo sapiens (human): 54331Help
Entry
54331             CDS       T01001                                 

Gene name
GNG2
Definition
(RefSeq) G protein subunit gamma 2
  KO
K07826  guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
Organism
hsa  Homo sapiens (human)
Pathway
hsa04014  Ras signaling pathway
hsa04062  Chemokine signaling pathway
hsa04151  PI3K-Akt signaling pathway
hsa04371  Apelin signaling pathway
hsa04713  Circadian entrainment
hsa04723  Retrograde endocannabinoid signaling
hsa04724  Glutamatergic synapse
hsa04725  Cholinergic synapse
hsa04726  Serotonergic synapse
hsa04727  GABAergic synapse
hsa04728  Dopaminergic synapse
hsa04926  Relaxin signaling pathway
hsa05032  Morphine addiction
hsa05034  Alcoholism
hsa05167  Kaposi's sarcoma-associated herpesvirus infection
hsa05200  Pathways in cancer
Network
N00152  CXCR-GNB/G-ERK signaling pathway
N00153  CXCR-GNB/G-PI3K-JNK signaling pathway
N00154  CXCR-GNB/G-PI3K-AKT signaling pathway
N00157  KSHV vGPCR to GNB/G-ERK signaling pathway
N00158  KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
N00178  KSHV vGPCR to GNB/G-PI3K-JNK signaling pathway
N00206  KSHV vGPCR to host-cell-protein activation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 Environmental Information Processing
  Signal transduction
   04014 Ras signaling pathway
    54331 (GNG2)
   04371 Apelin signaling pathway
    54331 (GNG2)
   04151 PI3K-Akt signaling pathway
    54331 (GNG2)
 Organismal Systems
  Immune system
   04062 Chemokine signaling pathway
    54331 (GNG2)
  Endocrine system
   04926 Relaxin signaling pathway
    54331 (GNG2)
  Nervous system
   04724 Glutamatergic synapse
    54331 (GNG2)
   04727 GABAergic synapse
    54331 (GNG2)
   04725 Cholinergic synapse
    54331 (GNG2)
   04728 Dopaminergic synapse
    54331 (GNG2)
   04726 Serotonergic synapse
    54331 (GNG2)
   04723 Retrograde endocannabinoid signaling
    54331 (GNG2)
  Environmental adaptation
   04713 Circadian entrainment
    54331 (GNG2)
 Human Diseases
  Cancers
   05200 Pathways in cancer
    54331 (GNG2)
  Substance dependence
   05032 Morphine addiction
    54331 (GNG2)
   05034 Alcoholism
    54331 (GNG2)
  Infectious diseases
   05163 Human cytomegalovirus infection
    54331 (GNG2)
   05167 Kaposi's sarcoma-associated herpesvirus infection
    54331 (GNG2)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   54331 (GNG2)
GTP-binding proteins [BR:hsa04031]
 Heterotrimeric G-proteins
  Gamma Subunits
   Gamma [OT]
    54331 (GNG2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: G-gamma CP12
Motif
Other DBs
NCBI-GeneID: 54331
NCBI-ProteinID: NP_001230702
OMIM: 606981
HGNC: 4404
Ensembl: ENSG00000186469
Vega: OTTHUMG00000171083
Pharos: P59768(Tbio)
UniProt: P59768
Structure
PDB: 

Position
14q22.1
AA seq 71 aa AA seqDB search
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENP
FREKKFFCAIL
NT seq 216 nt NT seq  +upstreamnt  +downstreamnt
atggccagcaacaacaccgccagcatagcacaagccaggaagctggtagagcagcttaag
atggaagccaatatcgacaggataaaggtgtccaaggcagctgcagatttgatggcctac
tgtgaagcacatgccaaggaagaccccctcctgacccctgttccggcttcagaaaacccg
tttagggagaagaagtttttctgtgccatcctttaa

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