KEGG   Homo sapiens (human): 5435Help
Entry
5435              CDS       T01001                                 

Gene name
POLR2F, HRBP14.4, POLRF, RPABC14.4, RPABC2, RPB14.4, RPB6, RPC15
Definition
(RefSeq) RNA polymerase II subunit F
  KO
K03014  DNA-directed RNA polymerases I, II, and III subunit RPABC2
Organism
hsa  Homo sapiens (human)
Pathway
hsa03020  RNA polymerase
hsa04623  Cytosolic DNA-sensing pathway
hsa05016  Huntington disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09121 Transcription
   03020 RNA polymerase
    5435 (POLR2F)
 09150 Organismal Systems
  09151 Immune system
   04623 Cytosolic DNA-sensing pathway
    5435 (POLR2F)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    5435 (POLR2F)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    5435 (POLR2F)
   03400 DNA repair and recombination proteins [BR:hsa03400]
    5435 (POLR2F)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   RNA polymerase II
    Pol I, II, III common subunits
     5435 (POLR2F)
  RNA polymerase III system
   RNA polymerase III
     5435 (POLR2F)
  RNA polymerase I system
   RNA polymerase I
     5435 (POLR2F)
DNA repair and recombination proteins [BR:hsa03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   NER (nucleotide excision repair)
    TCR (transcription coupled repair) factors
     DNA-directed RNA polymerase II complex
      5435 (POLR2F)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: RNA_pol_Rpb6 BDHCT_assoc
Motif
Other DBs
NCBI-GeneID: 5435
NCBI-ProteinID: NP_068809
OMIM: 604414
HGNC: 9193
Ensembl: ENSG00000100142
Vega: OTTHUMG00000151160
Pharos: P61218(Tbio)
UniProt: P61218
Structure
PDB: 

Position
22q13.1
AA seq 127 aa AA seqDB search
MSDNEDNFDGDDFDDVEEDEGLDDLENAEEEGQENVEILPSGERPQANQKRITTPYMTKY
ERARVLGTRALQIAMCAPVMVELEGETDPLLIAMKELKARKIPIIIRRYLPDGSYEDWGV
DELIITD
NT seq 384 nt NT seq  +upstreamnt  +downstreamnt
atgtcagacaacgaggacaattttgatggcgacgactttgatgatgtggaggaggatgaa
gggctagatgacttggagaatgccgaagaggaaggccaggagaatgtcgagatcctcccc
tctggggagcgaccgcaggccaaccagaagcgaatcaccacaccatacatgaccaagtac
gagcgagcccgcgtgctgggcacccgagcgctccagattgcgatgtgtgcccctgtgatg
gtggagctggagggggagacagatcctctgctcattgccatgaaggaactcaaggcccga
aagatccccatcatcattcgccgttacctgccagatgggagctatgaagactggggggtg
gacgagctcatcatcaccgactga

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