KEGG   Homo sapiens (human): 5444Help
Entry
5444              CDS       T01001                                 

Gene name
PON1, ESA, MVCD5, PON
Definition
(RefSeq) paraoxonase 1
  KO
K01045  arylesterase / paraoxonase [EC:3.1.1.2 3.1.8.1]
Organism
hsa  Homo sapiens (human)
Disease
H01457  Diabetic retinopathy
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5444 (PON1)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.2  arylesterase
     5444 (PON1)
   3.1.8  Phosphoric-triester hydrolases
    3.1.8.1  aryldialkylphosphatase
     5444 (PON1)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of hepatic cells
   5444 (PON1)
  Exosomal proteins of other cancer cells
   5444 (PON1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Arylesterase SGL Str_synth Lactonase
Motif
Other DBs
NCBI-GeneID: 5444
NCBI-ProteinID: NP_000437
OMIM: 168820
HGNC: 9204
Ensembl: ENSG00000005421
Vega: OTTHUMG00000153894
Pharos: P27169(Tbio)
UniProt: P27169
Position
7q21.3
AA seq 355 aa AA seqDB search
MAKLIALTLLGMGLALFRNHQSSYQTRLNALREVQPVELPNCNLVKGIETGSEDLEILPN
GLAFISSGLKYPGIKSFNPNSPGKILLMDLNEEDPTVLELGITGSKFDVSSFNPHGISTF
TDEDNAMYLLVVNHPDAKSTVELFKFQEEEKSLLHLKTIRHKLLPNLNDIVAVGPEHFYG
TNDHYFLDPYLQSWEMYLGLAWSYVVYYSPSEVRVVAEGFDFANGINISPDGKYVYIAEL
LAHKIHVYEKHANWTLTPLKSLDFNTLVDNISVDPETGDLWVGCHPNGMKIFFYDSENPP
ASEVLRIQNILTEEPKVTQVYAENGTVLQGSTVASVYKGKLLIGTVFHKALYCEL
NT seq 1068 nt NT seq  +upstreamnt  +downstreamnt
atggcgaagctgattgcgctcaccctcttggggatgggactggcactcttcaggaaccac
cagtcttcttaccaaacacgacttaatgctctccgagaggtacaacccgtagaacttcct
aactgtaatttagttaaaggaatcgaaactggctctgaagacttggagatactgcctaat
ggactggctttcattagctctggattaaagtatcctggaataaagagcttcaaccccaac
agtcctggaaaaatacttctgatggacctgaatgaagaagatccaacagtgttggaattg
gggatcactggaagtaaatttgatgtatcttcatttaaccctcatgggattagcacattc
acagatgaagataatgccatgtacctcctggtggtgaaccatccagatgccaagtccaca
gtggagttgtttaaatttcaagaagaagaaaaatcgcttttgcatctaaaaaccatcaga
cataaacttctgcctaatttgaatgatattgttgctgtgggacctgagcacttttatggc
acaaatgatcactattttcttgacccctacttacaatcctgggagatgtatttgggttta
gcgtggtcgtatgttgtctactatagtccaagtgaagttcgagtggtggcagaaggattt
gattttgctaatggaatcaacatttcacccgatggcaagtatgtctatatagctgagttg
ctggctcataagattcatgtgtatgaaaagcatgctaattggactttaactccattgaag
tcccttgactttaataccctcgtggataacatatctgtggatcctgagacaggagacctt
tgggttggatgccatcccaatggcatgaaaatcttcttctatgactcagagaatcctcct
gcatcagaggtgcttcgaatccagaacattctaacagaagaacctaaagtgacacaggtt
tatgcagaaaatggcacagtgttgcaaggcagtacagttgcctctgtgtacaaagggaaa
ctgctgattggcacagtgtttcacaaagctctttactgtgagctctaa

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