KEGG   Homo sapiens (human): 54681Help
Entry
54681             CDS       T01001                                 

Gene name
P4HTM, EGLN4, HIFPH4, P4H-TM, PH-4, PH4, PHD4
Definition
(RefSeq) prolyl 4-hydroxylase, transmembrane
  KO
K06711  hypoxia-inducible factor prolyl 4-hydroxylase [EC:1.14.11.-]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09190 Not Included in Pathway or Brite
  09191 Unclassified: metabolism
   99980 Enzymes with EC numbers
    54681 (P4HTM)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.-  
     54681 (P4HTM)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 2OG-FeII_Oxy_3 EF-hand_7 EF-hand_1 EF-hand_5 EF-hand_6 EF-hand_8
Motif
Other DBs
NCBI-GeneID: 54681
NCBI-ProteinID: NP_808808
OMIM: 614584
HGNC: 28858
Ensembl: ENSG00000178467
Vega: OTTHUMG00000074057
Pharos: Q9NXG6(Tchem)
UniProt: Q9NXG6
Position
3p21.31; 3p21.3
AA seq 502 aa AA seqDB search
MAAAAVTGQRPETAAAEEASRPQWAPPDHCQAQAAAGLGDGEDAPVRPLCKPRGICSRAY
FLVLMVFVHLYLGNVLALLLFVHYSNGDESSDPGPQHRAQGPGPEPTLGPLTRLEGIKVG
HERKVQLVTDRDHFIRTLSLKPLLFEIPGFLTDEECRLIIHLAQMKGLQRSQILPTEEYE
EAMSTMQVSQLDLFRLLDQNRDGHLQLREVLAQTRLGNGWWMTPESIQEMYAAIKADPDG
DGVLSLQEFSNMDLRDFHKYMRSHKAESSELVRNSHHTWLYQGEGAHHIMRAIRQRVLRL
TRLSPEIVELSEPLQVVRYGEGGHYHAHVDSGPVYPETICSHTKLVANESVPFETSCRYM
TVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQGTAVF
WYNYLPDGQGWVGDVDDYSLHGGCLVTRGTKWIANNWINVDPSRARQALFQQEMARLARE
GGTDSQPEWALDRAYRDARVEL
NT seq 1509 nt NT seq  +upstreamnt  +downstreamnt
atggcggcagcggcggtgacaggccagcggcctgagaccgcggcggccgaggaggcctcg
aggccgcagtgggcgccgccagaccactgccaggctcaggcggcggccgggctgggcgac
ggcgaggacgcaccggtgcgtccgctgtgcaagccccgcggcatctgctcgcgcgcctac
ttcctggtgctgatggtgttcgtgcacctgtacctgggtaacgtgctggcgctgctgctc
ttcgtgcactacagcaacggcgacgaaagcagcgatcccgggccccaacaccgtgcccag
ggccccgggcccgagcccaccttaggtcccctcacccggctggagggcatcaaggtgggg
cacgagcgtaaggtccagctggtcaccgacagggatcacttcatccgaaccctcagcctc
aagccgctgctcttcgaaatccccggcttcctgactgatgaagagtgtcggctcatcatc
catctggcgcagatgaaggggttacagcgcagccagatcctgcctactgaagagtatgaa
gaggcaatgagcactatgcaggtcagccagctggacctcttccggctgctggaccagaac
cgtgatgggcaccttcagctccgtgaggttctggcccagactcgcctgggaaatggatgg
tggatgactccagagagcattcaggagatgtacgccgcgatcaaggctgaccctgatggt
gacggagtgctgagtctgcaggagttctccaacatggaccttcgggacttccacaagtac
atgaggagccacaaggcagagtccagtgagctggtgcggaacagccaccatacctggctc
taccagggtgagggtgcccaccacatcatgcgtgccatccgccagagggtgctgcgcctc
actcgcctgtcgcctgagatcgtggagctcagcgagccgctgcaggttgttcgatatggt
gaggggggccactaccatgcccacgtggacagtgggcctgtgtacccagagaccatctgc
tcccataccaagctggtagccaacgagtctgtacccttcgagacctcctgccgctacatg
acagtgctgttttatttgaacaacgtcactggtgggggcgagactgttttccctgtagca
gataacagaacctacgatgaaatgagtctgattcaggatgacgtggacctccgtgacaca
cggaggcactgtgacaagggaaacctgcgtgtcaagccccaacagggcacagcagtcttc
tggtacaactacctgcctgatgggcaaggttgggtgggtgacgtagacgactactcgctg
cacgggggctgcctggtcacgcgcggcaccaagtggattgccaacaactggattaatgtg
gaccccagccgagcgcggcaagcgctgttccaacaggagatggcccgccttgcccgagaa
gggggcaccgactcacagcccgagtgggctctggaccgggcctaccgcgatgcgcgcgtg
gaactctga

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