KEGG T01001: 5478

Homo sapiens (human): 5478

Entry

5478 CDS T01001

Gene name

PPIA, CYPA, CYPH, HEL-S-69p

Definition

(RefSeq) peptidylprolyl isomerase A

K03767

peptidyl-prolyl cis-trans isomerase A (cyclophilin A) [EC:5.2.1.8]

Organism

hsa Homo sapiens (human)

Pathway

hsa04217

Necroptosis

Brite

KEGG Orthology (KO) [BR:hsa00001]
09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    5478 (PPIA)
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:hsa03110]
    5478 (PPIA)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    5478 (PPIA)
Enzymes [BR:hsa01000]
5. Isomerases
  5.2  cis-trans-Isomerases
   5.2.1  cis-trans Isomerases (only sub-subclass identified to date)
    5.2.1.8  peptidylprolyl isomerase
     5478 (PPIA)
Chaperones and folding catalysts [BR:hsa03110]
Protein folding catalysts
  Peptidyl prolyl isomerase
   Cyclophilin
    5478 (PPIA)
Exosome [BR:hsa04147]
Exosomal proteins
  Proteins found in most exosomes
   5478 (PPIA)

SSDB

Motif

Pfam:

Pro_isomerase

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

OMIM:

HGNC:

Ensembl:

Vega:

Pharos:

P62937(Tclin)

UniProt:

P62937 V9HWF5

Structure

PDB:

5F66 4N1M 6GS6 6GJL 4YUO 2X25 5LUD 3K0M 6GJY 5NOU 4YUH 6GJM 5NOS 6GJJ 4YUI 3K0N 5T9Z 2X2A 4YUJ 4YUL 5WC7 5NOY 5NOT 4N1S 5NOW 5TA2 4YUG 4YUK 5NOX 6BTA 5TA4 4YUM 4N1N 3K0O 4YUN 1AWQ 1AWR 6GJI 5NOQ 1YND 5NOZ 2CPL 2CYH 4N1Q 3K0P 1W8M 4IPZ 6GJR 6GJN 5KUL 5KUN 5KUO 5KUQ 5KUR 5KUS 5KUU 5KUV 5KUW 5KUZ 5KV0 5KV1 5KV2 5KV3 5KV4 5KV5 5KV6 5KV7 1W8V 1M9X 1M9E 1M9F 4YUP 4N1O 1MIK 5NOR 4N1R 2XGY 1W8L 1CWK 1CWL 1CWJ 1BCK 1FGL 1CWO 1CWH 1CWF 1CWC 4N1P 2ALF 1M9Y 1M9D 1CWI 3CYH 6GJP 2X2D 5NOV 5T9W 1M9C 1VBS 1CWM 1NMK 4CYH 5CYH 1CWA 2RMA 2RMB 3RDD 3ODI 1CWB 5T9U 1VBT 3ODL 3K0Q 1AWU 1AWV 1AK4 1RMH 2X2C 3K0R 1ZKF 1AWT 1AWS 1M63 1MF8 5FJB 2N0T 2MZU 2MS4 1OCA 3CYS

Position

7p13

AA seq 165 aa
MVNPTVFFDIAVDGEPLGRVSFELFADKVPKTAENFRALSTGEKGFGYKGSCFHRIIPGF
MCQGGDFTRHNGTGGKSIYGEKFEDENFILKHTGPGILSMANAGPNTNGSQFFICTAKTE
WLDGKHVVFGKVKEGMNIVEAMERFGSRNGKTSKKITIADCGQLE

NT seq 498 nt +upstreamnt +downstreamnt
atggtcaaccccaccgtgttcttcgacattgccgtcgacggcgagcccttgggccgcgtc
tcctttgagctgtttgcagacaaggtcccaaagacagcagaaaattttcgtgctctgagc
actggagagaaaggatttggttataagggttcctgctttcacagaattattccagggttt
atgtgtcagggtggtgacttcacacgccataatggcactggtggcaagtccatctatggg
gagaaatttgaagatgagaacttcatcctaaagcatacgggtcctggcatcttgtccatg
gcaaatgctggacccaacacaaatggttcccagtttttcatctgcactgccaagactgag
tggttggatggcaagcatgtggtgtttggcaaagtgaaagaaggcatgaatattgtggag
gccatggagcgctttgggtccaggaatggcaagaccagcaagaagatcaccattgctgac
tgtggacaactcgaataa

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