KEGG   Homo sapiens (human): 54901
Entry
54901             CDS       T01001                                 
Symbol
CDKAL1
Name
(RefSeq) CDK5 regulatory subunit associated protein 1 like 1
  KO
K15865  threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
Organism
hsa  Homo sapiens (human)
Disease
H00409  Type 2 diabetes mellitus
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03016 Transfer RNA biogenesis [BR:hsa03016]
    54901 (CDKAL1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.8  Transferring sulfur-containing groups
   2.8.4  Transferring alkylthio groups
    2.8.4.5  tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase
     54901 (CDKAL1)
Transfer RNA biogenesis [BR:hsa03016]
 Eukaryotic type
  tRNA modification factors
   Methylthiotransferase
    54901 (CDKAL1)
SSDB
Motif
Pfam: UPF0004 Radical_SAM TRAM
Other DBs
NCBI-GeneID: 54901
NCBI-ProteinID: NP_060244
OMIM: 611259
HGNC: 21050
Ensembl: ENSG00000145996
Pharos: Q5VV42(Tbio)
UniProt: Q5VV42
Position
6:20534457..21232404
AA seq 579 aa
MPSASCDTLLDDIEDIVSQEDSKPQDRHFVRKDVVPKVRRRNTQKYLQEEENSPPSDSTI
PGIQKIWIRTWGCSHNNSDGEYMAGQLAAYGYKITENASDADLWLLNSCTVKNPAEDHFR
NSIKKAQEENKKIVLAGCVPQAQPRQDYLKGLSIIGVQQIDRVVEVVEETIKGHSVRLLG
QKKDNGRRLGGARLDLPKIRKNPLIEIISINTGCLNACTYCKTKHARGNLASYPIDELVD
RAKQSFQEGVCEIWLTSEDTGAYGRDIGTNLPTLLWKLVEVIPEGAMLRLGMTNPPYILE
HLEEMAKILNHPRVYAFLHIPVQSASDSVLMEMKREYCVADFKRVVDFLKEKVPGITIAT
DIICGFPGETDQDFQETVKLVEEYKFPSLFINQFYPRPGTPAAKMEQVPAQVKKQRTKDL
SRVFHSYSPYDHKIGERQQVLVTEESFDSKFYVAHNQFYEQVLVPKNPAFMGKMVEVDIY
ESGKHFMKGQPVSDAKVYTPSISKPLAKGEVSGLTKDFRNGLGNQLSSGSHTSAASQCDS
ASSRMVLPMPRLHQDCALRMSVGLALLGLLFAFFVKVYN
NT seq 1740 nt   +upstreamnt  +downstreamnt
atgccttctgcatcctgtgatacactactggatgacatcgaagatatcgtgtctcaggaa
gattcaaaaccacaagataggcattttgtaagaaaggatgttgtcccgaaggtacgaagg
cgaaatacccaaaaatatttgcaagaggaagaaaacagtccaccaagtgacagcactatt
ccaggcatacagaaaatttggatacgaacatggggttgttctcataataattcagatgga
gaatatatggctggacagctagctgcttatggctataaaattacagaaaatgcatccgat
gcagatttatggctcctgaacagttgcactgtaaaaaacccagctgaagaccactttaga
aactcaattaaaaaagctcaagaggagaacaagaaaatcgtactggctggatgcgttcct
caagcccagcctcgccaggactaccttaagggactgagtatcattggggttcagcagata
gatcgtgtggtagaagttgtggaggagacaattaaaggtcactctgtgagactgctgggt
cagaaaaaggataatggaaggcggcttgggggagcacgattggatttgccgaagattagg
aagaatccactgatagaaatcatttccatcaataccgggtgtctcaatgcttgtacctac
tgcaaaactaaacacgccagaggaaatttggccagttatccaattgatgaactagtagat
agagccaaacaatcttttcaagagggtgtttgtgagatatggttgaccagtgaagacacg
ggggcttatggcagagatattggcaccaatctccccacactcctgtggaaactggttgaa
gtgattcctgagggagcaatgctgaggcttggcatgacaaatccgccctatattttagag
catctggaggaaatggcaaaaatccttaatcaccccagagtctacgcttttctgcacata
ccagtccagtctgcctccgacagcgtactcatggaaatgaaaagagaatactgtgtggct
gacttcaaaagagtagtggattttctgaaagagaaagttcctggaataactattgctaca
gatattatctgtggttttcctggagaaacagatcaggattttcaagaaacagtgaaactt
gttgaagagtacaaattcccaagcctgtttattaaccaattttacccaagaccaggaact
cctgctgcaaaaatggaacaagttccagcacaagtgaaaaagcaaaggacaaaagatctt
tctcgggtgtttcattcttacagtccatatgatcacaagattggtgaaagacaacaagtg
ttagtaacagaagaatcttttgattccaagttttatgttgcacacaatcaattctatgag
caggttttagtgccaaagaaccctgcgttcatggggaagatggttgaagtggacatctat
gaatcaggcaaacattttatgaaagggcagccagtatctgatgccaaagtgtacacgccc
tccatcagcaaaccgctagcaaagggagaagtctcgggtttgacaaaggacttcagaaat
gggcttgggaaccagctgagttcaggatcccacacctctgctgcatctcagtgtgactca
gcgagttccagaatggtgctgcccatgccaaggctacatcaagactgtgcgctgaggatg
tccgtgggcttggctctgctgggtcttctttttgctttttttgtcaaggtctataattag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Disease (2)   
   KEGG DISEASE (1)   
   OMIM (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
   PHAROS (1)   
Protein sequence (19)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (17)   
DNA sequence (37)   
   RefSeq(nuc) (17)   
   GenBank (10)   
   EMBL (10)   
Protein domain (3)   
   Pfam (3)   
All databases (92)   

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