KEGG   Homo sapiens (human): 54901
Entry
54901             CDS       T01001                                 
Symbol
CDKAL1
Name
(RefSeq) CDKAL1 threonylcarbamoyladenosine tRNA methylthiotransferase
  KO
K15865  threonylcarbamoyladenosine tRNA methylthiotransferase CDKAL1 [EC:2.8.4.5]
Organism
hsa  Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03016 Transfer RNA biogenesis [BR:hsa03016]
    54901 (CDKAL1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.8  Transferring sulfur-containing groups
   2.8.4  Transferring alkylthio groups
    2.8.4.5  tRNA (N6-L-threonylcarbamoyladenosine37-C2)-methylthiotransferase
     54901 (CDKAL1)
Transfer RNA biogenesis [BR:hsa03016]
 Eukaryotic type
  tRNA modification factors
   Methylthiotransferase
    54901 (CDKAL1)
SSDB
Motif
Pfam: UPF0004 Radical_SAM TRAM
Other DBs
NCBI-GeneID: 54901
NCBI-ProteinID: NP_060244
OMIM: 611259
HGNC: 21050
Ensembl: ENSG00000145996
UniProt: Q5VV42
Position
6:20534457..21232404
AA seq 579 aa
MPSASCDTLLDDIEDIVSQEDSKPQDRHFVRKDVVPKVRRRNTQKYLQEEENSPPSDSTI
PGIQKIWIRTWGCSHNNSDGEYMAGQLAAYGYKITENASDADLWLLNSCTVKNPAEDHFR
NSIKKAQEENKKIVLAGCVPQAQPRQDYLKGLSIIGVQQIDRVVEVVEETIKGHSVRLLG
QKKDNGRRLGGARLDLPKIRKNPLIEIISINTGCLNACTYCKTKHARGNLASYPIDELVD
RAKQSFQEGVCEIWLTSEDTGAYGRDIGTNLPTLLWKLVEVIPEGAMLRLGMTNPPYILE
HLEEMAKILNHPRVYAFLHIPVQSASDSVLMEMKREYCVADFKRVVDFLKEKVPGITIAT
DIICGFPGETDQDFQETVKLVEEYKFPSLFINQFYPRPGTPAAKMEQVPAQVKKQRTKDL
SRVFHSYSPYDHKIGERQQVLVTEESFDSKFYVAHNQFYEQVLVPKNPAFMGKMVEVDIY
ESGKHFMKGQPVSDAKVYTPSISKPLAKGEVSGLTKDFRNGLGNQLSSGSHTSAASQCDS
ASSRMVLPMPRLHQDCALRMSVGLALLGLLFAFFVKVYN
NT seq 1740 nt   +upstreamnt  +downstreamnt
atgccttctgcatcctgtgatacactactggatgacatcgaagatatcgtgtctcaggaa
gattcaaaaccacaagataggcattttgtaagaaaggatgttgtcccgaaggtacgaagg
cgaaatacccaaaaatatttgcaagaggaagaaaacagtccaccaagtgacagcactatt
ccaggcatacagaaaatttggatacgaacatggggttgttctcataataattcagatgga
gaatatatggctggacagctagctgcttatggctataaaattacagaaaatgcatccgat
gcagatttatggctcctgaacagttgcactgtaaaaaacccagctgaagaccactttaga
aactcaattaaaaaagctcaagaggagaacaagaaaatcgtactggctggatgcgttcct
caagcccagcctcgccaggactaccttaagggactgagtatcattggggttcagcagata
gatcgtgtggtagaagttgtggaggagacaattaaaggtcactctgtgagactgctgggt
cagaaaaaggataatggaaggcggcttgggggagcacgattggatttgccgaagattagg
aagaatccactgatagaaatcatttccatcaataccgggtgtctcaatgcttgtacctac
tgcaaaactaaacacgccagaggaaatttggccagttatccaattgatgaactagtagat
agagccaaacaatcttttcaagagggtgtttgtgagatatggttgaccagtgaagacacg
ggggcttatggcagagatattggcaccaatctccccacactcctgtggaaactggttgaa
gtgattcctgagggagcaatgctgaggcttggcatgacaaatccgccctatattttagag
catctggaggaaatggcaaaaatccttaatcaccccagagtctacgcttttctgcacata
ccagtccagtctgcctccgacagcgtactcatggaaatgaaaagagaatactgtgtggct
gacttcaaaagagtagtggattttctgaaagagaaagttcctggaataactattgctaca
gatattatctgtggttttcctggagaaacagatcaggattttcaagaaacagtgaaactt
gttgaagagtacaaattcccaagcctgtttattaaccaattttacccaagaccaggaact
cctgctgcaaaaatggaacaagttccagcacaagtgaaaaagcaaaggacaaaagatctt
tctcgggtgtttcattcttacagtccatatgatcacaagattggtgaaagacaacaagtg
ttagtaacagaagaatcttttgattccaagttttatgttgcacacaatcaattctatgag
caggttttagtgccaaagaaccctgcgttcatggggaagatggttgaagtggacatctat
gaatcaggcaaacattttatgaaagggcagccagtatctgatgccaaagtgtacacgccc
tccatcagcaaaccgctagcaaagggagaagtctcgggtttgacaaaggacttcagaaat
gggcttgggaaccagctgagttcaggatcccacacctctgctgcatctcagtgtgactca
gcgagttccagaatggtgctgcccatgccaaggctacatcaagactgtgcgctgaggatg
tccgtgggcttggctctgctgggtcttctttttgctttttttgtcaaggtctataattag

  All links  
Disease (1)   
   OMIM (1)   
Gene (16)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (3)   
   OC (1)   
Protein sequence (27)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (25)   
DNA sequence (52)   
   RefSeq(nuc) (32)   
   GenBank (10)   
   EMBL (10)   
Protein domain (3)   
   Pfam (3)   
All databases (99)   

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