KEGG   Homo sapiens (human): 5493
Entry
5493              CDS       T01001                                 
Symbol
PPL
Name
(RefSeq) periplakin
  KO
K10386  periplakin
Organism
hsa  Homo sapiens (human)
Pathway
hsa04382  Cornified envelope formation
Network
nt06545  Cornified envelope formation
  Element
N01922  Localization of envoplakin and periplakin to the plasma membrane (PM)
N01923  Closslinking of envoplakin, periplakin and involucrin
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09150 Organismal Systems
  09158 Development and regeneration
   04382 Cornified envelope formation
    5493 (PPL)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:hsa04812]
    5493 (PPL)
Cytoskeleton proteins [BR:hsa04812]
 Eukaryotic cytoskeleton proteins
  Intermediate filaments
   Intermediate filament-binding proteins
    5493 (PPL)
SSDB
Motif
Pfam: Plectin_PPL SR_desmoplakin_3 Spectrin_1st_PEPL SH3_10 Plectin Spectrin
Other DBs
NCBI-GeneID: 5493
NCBI-ProteinID: NP_002696
OMIM: 602871
HGNC: 9273
Ensembl: ENSG00000118898
UniProt: O60437
Structure
Position
16:complement(4882507..4937148)
AA seq 1756 aa
MNSLFRKRNKGKYSPTVQTRSISNKELSELIEQLQKNADQVEKNIVDTEAKMQSDLARLQ
EGRQPEHRDVTLQKVLDSEKLLYVLEADAAIAKHMKHPQGDMIAEDIRQLKERVTNLRGK
HKQIYRLAVKEVDPQVNWAALVEEKLDKLNNQSFGTDLPLVDHQVEEHNIFHNEVKAIGP
HLAKDGDKEQNSELRAKYQKLLAASQARQQHLSSLQDYMQRCTNELYWLDQQAKGRMQYD
WSDRNLDYPSRRRQYENFINRNLEAKEERINKLHSEGDQLLAAEHPGRNSIEAHMEAVHA
DWKEYLNLLICEESHLKYMEDYHQFHEDVKDAQELLRKVDSDLNQKYGPDFKDRYQIELL
LRELDDQEKVLDKYEDVVQGLQKRGQQVVPLKYRRETPLKPIPVEALCDFEGEQGLISRG
YSYTLQKNNGESWELMDSAGNKLIAPAVCFVIPPTDPEALALADSLGSQYRSVRQKAAGS
KRTLQQRYEVLKTENPGDASDLQGRQLLAGLDKVASDLDRQEKAITGILRPPLEQGRAVQ
DSAERAKDLKNITNELLRIEPEKTRSTAEGEAFIQALPGSGTTPLLRTRVEDTNRKYEHL
LQLLDLAQEKVDVANRLEKSLQQSWELLATHENHLNQDDTVPESSRVLDSKGQELAAMAC
ELQAQKSLLGEVEQNLQAAKQCSSTLASRFQEHCPDLERQEAEVHKLGQRFNNLRQQVER
RAQSLQSAKAAYEHFHRGHDHVLQFLVSIPSYEPQETDSLSQMETKLKNQKNLLDEIASR
EQEVQKICANSQQYQQAVKDYELEAEKLRSLLDLENGRRSHVSKRARLQSPATKVKEEEA
ALAAKFTEVYAINRQRLQNLEFALNLLRQQPEVEVTHETLQRNRPDSGVEEAWKIRKELD
EETERRRQLENEVKSTQEEIWTLRNQGPQESVVRKEVLKKVPDPVLEESFQQLQRTLAEE
QHKNQLLQEELEALQLQLRALEQETRDGGQEYVVKEVLRIEPDRAQADEVLQLREELEAL
RRQKGAREAEVLLLQQRVAALAEEKSRAQEKVTEKEVVKLQNDPQLEAEYQQLQEDHQRQ
DQLREKQEEELSFLQDKLKRLEKERAMAEGKITVKEVLKVEKDAATEREVSDLTRQYEDE
AAKARASQREKTELLRKIWALEEENAKVVVQEKVREIVRPDPKAESEVANLRLELVEQER
KYRGAEEQLRSYQSELEALRRRGPQVEVKEVTKEVIKYKTDPEMEKELQRLREEIVDKTR
LIERCDLEIYQLKKEIQALKDTKPQVQTKEVVQEILQFQEDPQTKEEVASLRAKLSEEQK
KQVDLERERASQEEQIARKEEELSRVKERVVQQEVVRYEEEPGLRAEASAFAESIDVELR
QIDKLRAELRRLQRRRTELERQLEELERERQARREAEREVQRLQQRLAALEQEEAEAREK
VTHTQKVVLQQDPQQAREHALLRLQLEEEQHRRQLLEGELETLRRKLAALEKAEVKEKVV
LSESVQVEKGDTEQEIQRLKSSLEEESRSKRELDVEVSRLEARLSELEFHNSKSSKELDF
LREENHKLQLERQNLQLETRRLQSEINMAATETRDLRNMTVADSGTNHDSRLWSLERELD
DLKRLSKDKDLEIDELQKRLGSVAVKREQRENHLRRSIVVIHPDTGRELSPEEAHRAGLI
DWNMFVKLRSQECDWEEISVKGPNGESSVIHDRKSGKKFSIEEALQSGRLTPAQYDRYVN
KDMSIQELAVLVSGQK
NT seq 5271 nt   +upstreamnt  +downstreamnt
atgaactcgctcttcaggaagagaaacaaaggcaaatacagccccactgtgcagacccgg
agcatctctaacaaggagctctcggagctgatcgagcagctgcagaagaatgccgaccag
gtggagaagaacatcgtggacacagaggccaagatgcagagtgacctggctcggctgcag
gagggtcggcagcctgagcaccgggacgtgaccctgcagaaggtgttggactctgagaag
ctgctctatgtgctagaggcggatgcggccattgccaagcacatgaagcacccacagggg
gacatgatcgccgaggatatccgccagctgaaggagcgtgtgaccaacctgcgcgggaaa
cacaagcagatctacaggctggcggtgaaggaagtggatccacaggtcaactgggcggca
ctggtggaggagaagctggacaagctgaacaaccagagctttgggactgacctgccgctg
gtggaccaccaagtggaggagcataacatcttccacaatgaggtcaaggccatcgggccc
cacctggccaaggacggggacaaggagcagaacagcgaactccgggccaagtaccagaaa
ctgctggcagcatcacaggcccggcagcagcacctgagttcgctgcaggactacatgcag
cgctgcaccaatgagctgtactggctggaccagcaggccaagggccgcatgcagtacgac
tggagtgaccgcaacctcgactaccccagccgccggcgccagtatgagaatttcatcaac
cggaacctggaggccaaagaggagagaatcaacaaactgcacagcgagggcgaccagctg
ctggcggccgagcaccccgggaggaactccattgaggcgcacatggaggctgtgcacgca
gactggaaggagtacctgaacctgctcatctgcgaggagagccacctcaagtacatggag
gactaccaccagtttcacgaagacgtgaaggacgctcaggagctgctgcgcaaggtggac
tcggacctgaaccagaagtatggccctgacttcaaggaccggtaccagattgagctgctg
ctgcgggagctggatgaccaggagaaggtgctggacaagtatgaggacgtggtgcagggg
ctgcagaagcgaggccagcaggtggtgcccctcaagtaccgccgggagactccgctcaag
cccatccccgtggaggcactctgtgactttgagggggagcagggcctgatctcgcggggc
tacagctacaccctgcagaagaacaacggggagagctgggagctcatggacagcgctggg
aacaagctgattgctccggccgtgtgttttgtgatcccccccacagaccctgaggccctg
gctctggctgacagcctgggcagccagtaccggagcgtgcggcagaaggcagctgggagc
aaacgcacgctgcagcagcggtatgaggtgctgaagaccgagaatcccggagatgcctct
gacctacaggggcggcagctgctggctggcttggacaaggtggccagcgacctggaccgg
caggagaaggccatcacagggatcctgcggccaccactggagcaaggccgggctgtgcag
gacagtgccgagcgggccaaggacctcaagaacatcaccaacgagctactgcggattgaa
cctgagaagacgcggagcacggctgagggcgaagccttcatccaggccctcccaggcagt
ggcaccacacccctgctgaggacccgggtggaggacaccaaccggaaatacgagcacctc
ctgcagctgctggacttggcccaggagaaggttgatgtggccaaccgcctggagaagagc
ctgcagcagagctgggagttgctggccacacacgagaaccatctgaatcaggatgacaca
gtgcctgagagcagccgtgtcctggacagcaaggggcaggagctggcggccatggcctgt
gagttacaggcccagaagtccctcctgggtgaggtggagcagaacttgcaggcggccaag
cagtgctcgagcacactggccagccgcttccaggagcactgtccggacctggagcgccag
gaggccgaggtgcacaagctgggccagcgtttcaacaacctgcgccagcaggtggaacgc
agggcgcagagcctacagagcgccaaggcagcctacgagcacttccaccgcggccatgac
cacgtgctgcagttcctagtcagcatccccagttacgagccccaggagacagacagcctc
agccagatggagaccaagctgaagaaccagaagaacctgctagatgagatagcaagtagg
gagcaggaagtacagaagatctgtgccaattcccagcagtaccagcaagctgtaaaggac
tatgagttagaagcagaaaaactaaggtctcttctcgacttggagaatggaaggagaagc
cacgtgagcaagagagccaggctccaatctcctgccaccaaagtgaaggaagaggaagca
gcacttgccgccaagttcactgaagtttatgccatcaacagacagaggctgcagaatctg
gagtttgctctgaatctcctcagacagcagccggaagtagaagtgacccatgagaccctg
caaaggaataggccggactctggagtggaggaggcgtggaagatcaggaaggaactggat
gaggagactgagcggaggcggcagctggagaacgaggtcaagagcacccaggaagaaatc
tggaccttgaggaatcaggggcctcaggaatcggtggtgaggaaggaggtgctcaagaag
gtgccggatcccgtgctggaggagagcttccagcagctgcagcggacgctggcagaggag
cagcacaagaaccagctgctgcaggaggagctggaggcactgcagctgcagctgcgtgcc
ctggagcaggagaccagagacggggggcaggagtacgtggtcaaggaggtcctgcgcatc
gagcctgacagggcccaggcggatgaggtcttgcagctgcgggaggagctggaggcactg
aggcggcagaagggcgcccgggaggcagaggtgctcctcctgcagcagcgtgtggccgcc
ctggctgaagagaagagccgggcgcaggagaaggtcacagagaaagaggtggtgaaactg
cagaatgacccccagctggaggcagagtaccagcagctgcaggaggaccaccagcgccag
gaccagctcagggagaagcaggaggaggagctgagcttcctccaggacaagctcaagagg
ctagagaaggagcgggccatggccgagggcaagatcaccgtcaaggaggtgctcaaggtg
gagaaggacgcggccaccgagagggaggtcagcgatctcacccgccaatatgaggacgag
gctgccaaggctcgcgctagccagagggagaagacggagctgctccgaaagatatgggcc
ttggaggaggagaacgccaaagtggtggtgcaggagaaggtgcgggagatcgtgcggcca
gaccccaaggcggaaagtgaagtggcgaacctccgcctggagcttgtggagcaggagcga
aagtaccggggtgccgaggagcagctccggagctaccagagtgagctggaggccctcagg
aggcgaggcccccaggtggaagtcaaagaggtgactaaggaagtcattaagtacaagact
gaccctgagatggagaaggagcttcagcggctcagggaggagatcgtggacaagaccaga
ctgatcgaaaggtgtgatttagagatctaccagctgaaaaaggaaatccaggccctgaaa
gacaccaaaccccaggtccagaccaaagaggtggtccaggagatcctccaattccaagaa
gaccctcaaaccaaggaggaggtggcgtctctgagggcaaagctctcagaggagcagaag
aaacaagtggatctggagagggaaagagcttcccaggaagagcagatcgcccggaaagag
gaggagctctcgcgggtgaaggaaagggtggtgcagcaggaggtggtcaggtatgaggag
gagccaggcctgcgggccgaggcgagcgcctttgccgagagcatcgatgtggagctgcgg
cagattgacaagctgcgggcagagctgcggcggctgcagcgccggcgcaccgagcttgag
cggcagctggaggagctagagcgcgagcggcaggcccgcagggaggccgagcgcgaggta
cagcggttgcagcagcggctggcagcgctggagcaggaagaagctgaggcccgtgagaag
gtaacccatacgcagaaggtggtgctgcagcaggacccgcagcaggcgcgagagcatgcc
ctgctccgactccagctggaagaagagcagcaccggcggcagctcctggagggggagctc
gagaccctccggaggaaactggctgcactggagaaggcggaggtcaaggagaaggtggtg
ctctccgagagtgtccaggtggagaagggcgacaccgagcaagagatccagaggctcaag
agcagcctggaggaggagagccgcagcaagcgcgagctggacgtcgaggtgagccggctg
gaagccaggctttcggagctggaattccataactccaagtcatccaaggaactagacttt
ctgagggaagagaaccacaaattacagctggagaggcaaaacctgcagctggagacccga
aggctccaatcggaaatcaacatggcagcgacggaaacacgagacctgcggaacatgacc
gtggcggactctgggaccaaccatgactccagactgtggtccctggagagggaactggat
gacctcaagaggctctccaaggacaaagacctcgagatcgacgagctgcagaagcgcctg
ggctccgtggccgtcaagcgggagcagcgggagaaccacctgcggcgctccatcgtagtc
atccaccctgacacaggccgcgagctgtccccggaggaagcccaccgtgccgggctcatt
gactggaacatgttcgtgaaactcagaagccaggagtgcgactgggaggagatctcagtg
aagggtcccaatggggagtcctcagtgatacacgacaggaagtctggcaagaagttctcc
atcgaagaggccctgcagagtggcaggctgacccctgctcagtatgaccgctatgtcaac
aaggatatgtccatccaggagctggcggtcttggtatctgggcagaagtag

  All links  
Disease (1)   
   OMIM (1)   
Gene (54)   
   RefGene (49)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (7)   
DNA sequence (21)   
   RefSeq(nuc) (7)   
   GenBank (7)   
   EMBL (7)   
3D Structure (1)   
   PDB (1)   
Protein domain (6)   
   Pfam (6)   
All databases (92)   

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