KEGG   Homo sapiens (human): 5495
Entry
5495              CDS       T01001                                 
Symbol
PPM1B, PP2C-beta, PP2C-beta-X, PP2CB, PP2CBETA, PPC2BETAX
Name
(RefSeq) protein phosphatase, Mg2+/Mn2+ dependent 1B
  KO
K04461  protein phosphatase 1B [EC:3.1.3.16]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04010  MAPK signaling pathway
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    5495 (PPM1B)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5495 (PPM1B)
Enzymes [BR:hsa01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     5495 (PPM1B)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Mg2+- or Mn2+- dependent protein phosphatases (PPMs)
   PPM1 phosphatases (PP2C)
    5495 (PPM1B)
SSDB
Motif
Pfam: PP2C PP2C_C PP2C_2 DUF3456
Other DBs
NCBI-GeneID: 5495
NCBI-ProteinID: NP_002697
OMIM: 603770
HGNC: 9276
Ensembl: ENSG00000138032
Pharos: O75688(Tchem)
UniProt: O75688
Structure
Position
2:44168875..44246928
AA seq 479 aa
MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYD
GHAGSRVANYCSTHLLEHITTNEDFRAAGKSGSALELSVENVKNGIRTGFLKIDEYMRNF
SDLRNGMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERI
QNAGGSVMIQRVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIIL
ACDGIWDVMSNEELCEYVKSRLEVSDDLENVCNWVVDTCLHKGSRDNMSIVLVCFSNAPK
VSDEAVKKDSELDKHLESRVEEIMEKSGEEGMPDLAHVMRILSAENIPNLPPGGGLAGKR
NVIEAVYSRLNPHRESDGASDEAEESGSQGKLVEALRQMRINHRGNYRQLLEEMLTSYRL
AKVEGEESPAEPAATATSSNSDAGNPVTMQESHTESESGLAELDSSNEDAGTKMSGEKI
NT seq 1440 nt   +upstreamnt  +downstreamnt
atgggtgcatttttggataaacccaaaactgaaaaacataatgctcatggtgctgggaat
ggtttacgttatggcctgagcagcatgcaaggatggagagtggaaatggaagatgcacac
acagctgttgtaggtattcctcacggcttggaagactggtcattttttgcagtttatgat
ggtcatgctggatcccgagtggcaaattactgctcaacacatttattagaacacatcact
actaacgaagactttagggcagctggaaaatcaggatctgctcttgagctttcagtggaa
aatgttaagaatggtatcagaactggatttttgaaaattgatgaatacatgcgtaacttt
tcagacctcagaaacgggatggacaggagtggttcaactgcagtgggagttatgatttca
cctaagcatatctactttatcaactgtggtgattcacgtgctgttctgtataggaatgga
caagtctgcttttctacccaggatcacaaaccttgcaatccaagggaaaaggagcgaatc
caaaatgcaggaggcagcgtgatgatacaacgtgttaatggttcattagcagtatctcgt
gctctgggggactatgattacaagtgtgttgatggcaagggcccaacagaacaacttgtt
tctccagagcctgaggtttatgaaattttaagagcagaagaggatgaatttatcatcttg
gcttgtgatgggatctgggatgttatgagtaatgaggagctctgtgaatatgttaaatct
aggcttgaggtatctgatgacctggaaaatgtgtgcaattgggtagtggacacttgttta
cacaagggaagtcgagataacatgagtattgtactagtttgcttttcaaatgctcccaag
gtctcagatgaagcggtgaaaaaagattcagagttggataagcacttggaatcacgggtt
gaagagattatggagaagtctggcgaggaaggaatgcctgatcttgcccatgtcatgcgc
atcttgtctgcagaaaatatcccaaatttgcctcctgggggaggtcttgctggcaagcgt
aatgttattgaagctgtttatagtagactgaatccacatagagaaagtgatggggcctcc
gatgaagcagaggaaagtggatcacagggaaaattggtggaagctctcaggcaaatgaga
attaatcataggggaaactaccgacaacttctggaggagatgctgactagttacaggcta
gctaaagtagagggagaagaaagccctgctgaaccagctgccacagctacttcttcgaac
agtgatgctggaaacccagtgacaatgcaggaaagccatactgaatcagaaagtggtctt
gctgaattagacagctctaatgaagatgcagggacaaagatgagtggtgaaaaaatatga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (1)   
   OMIM (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (12)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
   PHAROS (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (51)   
   RefSeq(nuc) (13)   
   GenBank (19)   
   EMBL (19)   
3D Structure (1)   
   PDB (1)   
Protein domain (4)   
   Pfam (4)   
All databases (97)   

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