KEGG   Homo sapiens (human): 5524
Entry
5524              CDS       T01001                                 
Symbol
PTPA, PARK25, PP2A, PPP2R4, PR53
Name
(RefSeq) protein phosphatase 2 phosphatase activator
  KO
K17605  serine/threonine-protein phosphatase 2A activator
Organism
hsa  Homo sapiens (human)
Pathway
hsa04931  Insulin resistance
hsa05415  Diabetic cardiomyopathy
Disease
H00057  Parkinson disease
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    5524 (PTPA)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    5524 (PTPA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:hsa01009]
    5524 (PTPA)
Protein phosphatases and associated proteins [BR:hsa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-2 (PP2A)
    Other PP2-interacting proteins
     5524 (PTPA)
SSDB
Motif
Pfam: PTPA
Other DBs
NCBI-GeneID: 5524
NCBI-ProteinID: NP_821068
OMIM: 600756
HGNC: 9308
Ensembl: ENSG00000119383
UniProt: Q15257
Structure
Position
9:129110950..129148946
AA seq 358 aa
MAEGERQPPPDSSEEAPPATQNFIIPKKEIHTVPDMGKWKRSQAYADYIGFILTLNEGVK
GKKLTFEYRVSEMWNEVHEEKEQAAKQSVSCDECIPLPRAGHCAPSEAIEKLVALLNTLD
RWIDETPPVDQPSRFGNKAYRTWYAKLDEEAENLVATVVPTHLAAAVPEVAVYLKESVGN
STRIDYGTGHEAAFAAFLCCLCKIGVLRVDDQIAIVFKVFNRYLEVMRKLQKTYRMEPAG
SQGVWGLDDFQFLPFIWGSSQLIDHPYLEPRHFVDEKAVNENHKDYMFLECILFITEMKT
GPFAEHSNQLWNISAVPSWSKVNQGLIRMYKAECLEKFPVIQHFKFGSLLPIHPVTSG
NT seq 1077 nt   +upstreamnt  +downstreamnt
atggctgagggcgagcggcagccgccgccagattcttcagaggaggcccctccagccact
cagaacttcatcattccaaaaaaggagatccacacagttccagacatgggcaaatggaag
cgttctcaggcatacgctgactacatcggattcatccttaccctcaacgaaggtgtgaag
gggaagaagctgaccttcgagtacagagtctccgagatgtggaatgaggttcatgaggaa
aaggagcaggctgcaaagcagagtgtgtcctgcgatgaatgcataccattaccccgcgcc
gggcactgtgcaccttcggaggccattgagaaactagtcgctcttctcaacacgctggac
aggtggattgatgagactcctccagtggaccagccctctcggtttgggaataaggcatac
aggacctggtatgccaaacttgatgaggaagcagaaaacttggtggccacagtggtccct
acccatctggcagctgctgtgcctgaggtggctgtttacctaaaggagtcagtggggaac
tccacgcgcattgactacggcacagggcatgaggcagccttcgctgctttcctctgctgt
ctctgcaagattggggtgctccgggtggatgaccaaatagctattgtcttcaaggtgttc
aatcggtaccttgaggttatgcggaaactccagaaaacatacaggatggagccagccggc
agccagggagtgtggggtctggatgacttccagtttctgcccttcatctggggcagttcg
cagctgatagaccacccatacctggagcccagacactttgtggatgagaaggccgtgaat
gagaaccacaaggactacatgttcctggagtgtatcctgtttattaccgagatgaagact
ggcccatttgcagagcactccaaccagctgtggaacatcagcgccgtcccttcctggtcc
aaagtgaaccagggtctcatccgcatgtataaggccgagtgcctggagaagttccctgtg
atccagcacttcaagttcgggagcctgctgcccatccatcctgtcacgtcgggctag

  All links  
Disease (2)   
   OMIM (2)   
Gene (23)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (15)   
   OC (1)   
Protein sequence (18)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (16)   
DNA sequence (79)   
   RefSeq(nuc) (17)   
   GenBank (31)   
   EMBL (31)   
3D Structure (6)   
   PDB (6)   
Protein domain (1)   
   Pfam (1)   
All databases (129)   

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